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We propose Artificial Intelligence Prospective Randomized Observer Blinding Evaluation (AI-PROBE) for quantitative clinical performance evaluation of radiology AI systems within prospective randomized clinical trials. AI-PROBE encompasses a…

Medical Physics · Physics 2020-03-02 Axel Wismüller , Larry Stockmaster

Current pain assessment within hospitals often relies on self-reporting or non-specific EKG vital signs. This system leaves critically ill, sedated, and cognitively impaired patients vulnerable to undertreated pain and opioid overuse.…

Machine Learning · Computer Science 2025-10-08 Aavid Mathrawala , Dhruv Kurup , Josie Lau

Detecting seizure using brain neuroactivations recorded by intracranial electroencephalogram (iEEG) has been widely used for monitoring, diagnosing, and closed-loop therapy of epileptic patients, however, computational efficiency gains are…

Computer Vision and Pattern Recognition · Computer Science 2017-02-01 Nhan Truong , Levin Kuhlmann , Mohammad Reza Bonyadi , Jiawei Yang , Andrew Faulks , Omid Kavehei

Timely diagnosis is important for saving the life of epileptic patients. In past few years, a lot of treatments are available for epilepsy. These treatments require use of anti-seizure drugs but are not effective in controlling frequency of…

Machine Learning · Computer Science 2021-11-08 Shivam Gupta , Jyoti Meena , O. P Gupta

Electrical impedance tomography (EIT) is a non-invasive imaging method for recovering the internal conductivity of a physical body from electric boundary measurements. EIT combined with machine learning has shown promise for the…

To evaluate EEG data, one can count local maxima and minima on a fine scale, in a sliding window analysis. This straightforward calculation, which simplifies and improves previous work on permutation entropy, directly defines a good proxy…

Applications · Statistics 2017-10-03 Christoph Bandt

While analytics of sleep electroencephalography (EEG) holds certain advantages over other methods in clinical applications, high variability across subjects poses a significant challenge when it comes to deploying machine learning models…

Machine Learning · Computer Science 2023-10-05 Manoj Vishwanath , Steven Cao , Nikil Dutt , Amir M. Rahmani , Miranda M. Lim , Hung Cao

A methodology for understanding and de- tecting nonconvulsive seizures in individuals with sub- arachnoid hemorrhage is introduced. Specifically, begin- ning with an EEG signal, the power spectrum is esti- mated yielding a multivariate time…

Neurons and Cognition · Quantitative Biology 2013-06-03 D J Albers , J Claassen , M J Schmidt , G Hripcsak

Magnetoencephalography (MEG) scanner has been shown to be more accurate than other medical devices in detecting mild traumatic brain injury (mTBI). However, MEG scan data in certain spectrum ranges can be skewed, multimodal and…

Methodology · Statistics 2025-02-07 Jian Zhang , Gary Green

The study aims to investigate the similarities and differences in the brain damage caused by Hypoxia-Ischemia (HI), Hypoglycemia, and Epilepsy. Hypoglycemia poses a significant challenge in improving glycemic regulation for insulin-treated…

The Temporal Sampling Framework (TSF) theorizes that the characteristic phonological difficulties of dyslexia are caused by an atypical oscillatory sampling at one or more temporal rates. The LEEDUCA study conducted a series of…

Sleep staging is critical for assessing sleep quality and diagnosing sleep disorders. However, capturing both the spatial and temporal relationships within electroencephalogram (EEG) signals during different sleep stages remains…

Signal Processing · Electrical Eng. & Systems 2023-08-09 Xinliang Zhou , Chenyu Liu , Jiaping Xiao , Yang Liu

Electroencephalogram (EEG) provides noninvasive measures of brain activity and is found to be valuable for diagnosis of some chronic disorders. Specifically, pre-treatment EEG signals in alpha and theta frequency bands have demonstrated…

Applications · Statistics 2023-05-24 Bin Yang , Xingche Guo , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

The detection of interictal epileptiform discharge (IED) is crucial for the diagnosis of epilepsy, but automated methods often lack interpretability. This study proposes IED-RAG, an explainable multimodal framework for joint IED detection…

Signal Processing · Electrical Eng. & Systems 2026-02-17 Yu Zhu , Jiayang Guo , Jun Jiang , Peipei Gu , Xin Shu , Duo Chen

Electroencephalogram (EEG) signals are critical for detecting abnormal brain activity, but their high dimensionality and complexity pose significant challenges for effective analysis. In this paper, we propose CwA-T, a novel framework that…

Machine Learning · Computer Science 2024-12-25 Youshen Zhao , Keiji Iramina

Epilepsy is one of the most common neurological disorders. This disease requires reliable and efficient seizure detection methods. Electroencephalography (EEG) is the gold standard for seizure monitoring, but its manual analysis is a…

Signal Processing · Electrical Eng. & Systems 2025-12-17 Annika Stiehl , Nicolas Weeger , Christian Uhl , Dominic Bechtold , Nicole Ille , Stefan Geißelsöder

Blinks in electroencephalography (EEG) are often treated as unwanted artifacts. However, recent studies have demonstrated that blink rate and its variability are important physiological markers to monitor cognitive load, attention, and…

Machine Learning · Computer Science 2025-09-08 Artem Lensky , Yiding Qiu

Several methods have been developed to extract information from electroencephalograms (EEG). One of them is Phase-Amplitude Coupling (PAC) which is a type of Cross-Frequency Coupling (CFC) method, consisting in measure the synchronization…

Neurons and Cognition · Quantitative Biology 2021-04-13 Marco A. Formoso , Andrés Ortiz , Francisco J. Martínez-Murcia , Nicolás Gallego-Molina , Juan L. Luque

Epilepsy is a highly prevalent brain condition with many serious complications arising from it. The majority of patients which present to a clinic and undergo electroencephalogram (EEG) monitoring would be unlikely to experience seizures…

Signal Processing · Electrical Eng. & Systems 2023-12-14 Matthew McDougall , Hezam Albaqami , Ghulam Mubashar Hassan , Amitava Datta

Objective: A clinical decision support tool that automatically interprets EEGs can reduce time to diagnosis and enhance real-time applications such as ICU monitoring. Clinicians have indicated that a sensitivity of 95% with a specificity…