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DNA sequences encode critical genetic information, yet their variable length and discrete nature impede direct utilization in deep learning models. Existing DNA representation schemes convert sequences into numerical vectors but fail to…

Genomics · Quantitative Biology 2025-12-16 Zhiyuan Peng , Naifan Zhang , Yuanbo Tang , Yang Li

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Quantum circuits that generate coherent superpositions of stochastic processes are key to many downstream quantum-accelerated tasks, such as risk analysis, importance sampling, and DNA sequencing. However, traditional methods for designing…

Quantum Physics · Physics 2026-03-26 Ximing Wang , Chengran Yang , Chidambaram Aditya Somasundaram , Jayne Thompson , Mile Gu

An extension to a recently introduced architecture of clique-based neural networks is presented. This extension makes it possible to store sequences with high efficiency. To obtain this property, network connections are provided with…

Neural and Evolutionary Computing · Computer Science 2014-09-02 Xiaoran Jiang , Vincent Gripon , Claude Berrou , Michael Rabbat

Modern high-throughput gene perturbation screens are key technologies at the forefront of genetic research. Combined with rich phenotypic descriptors they enable researchers to observe detailed cellular reactions to experimental…

Molecular Networks · Quantitative Biology 2010-10-08 Florian Markowetz

DNA microarrays are a relatively new technology that can simultaneously measure the expression level of thousands of genes. They have become an important tool for a wide variety of biological experiments. One of the most common goals of DNA…

Methodology · Statistics 2013-07-02 Eric Bair

Process mining methods often analyze processes in terms of the individual end-to-end process runs. Process behavior, however, may materialize as a general state of many involved process components, which can not be captured by looking at…

Databases · Computer Science 2022-11-02 Bianka Bakullari , Wil M. P. van der Aalst

Due to its longevity and enormous information density, DNA is an attractive medium for archival data storage. Thanks to rapid technological advances, DNA storage is becoming practically feasible, as demonstrated by a number of experimental…

Information Theory · Computer Science 2022-11-11 Ilan Shomorony , Reinhard Heckel

We consider the problem of storing and retrieving information from synthetic DNA media. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on their collection of substrings…

Information Theory · Computer Science 2015-02-03 Han Mao Kiah , Gregory J. Puleo , Olgica Milenkovic

Printing custom DNA sequences is essential to scientific and biomedical research, but the technology can be used to manufacture plagues as well as cures. Just as ink printers recognize and reject attempts to counterfeit money, DNA…

Our ability to synthesize sensory data that preserves specific statistical properties of the real data has had tremendous implications on data privacy and big data analytics. The synthetic data can be used as a substitute for selective real…

Machine Learning · Computer Science 2017-02-01 Moustafa Alzantot , Supriyo Chakraborty , Mani B. Srivastava

Deoxyribonucleic acid (DNA) has shown great promise in enabling computational applications, most notably in the fields of DNA digital data storage and DNA computing. Information is encoded as DNA strands, which will naturally bind in…

Machine Learning · Computer Science 2021-10-22 David Buterez

Event cameras offer high temporal resolution and power efficiency, making them well-suited for edge AI applications. However, their high event rates present challenges for data transmission and processing. Subsampling methods provide a…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Hesam Araghi , Jan van Gemert , Nergis Tomen

Next Generation Sequencing (NGS), a recently evolved technology, have served a lot in the research and development sector of our society. This novel approach is a newbie and has critical advantages over the traditional Capillary…

Genomics · Quantitative Biology 2020-05-01 Khalid Raza , Sabahuddin Ahmad

Event cameras are novel sensors that report brightness changes in the form of a stream of asynchronous "events" instead of intensity frames. They offer significant advantages with respect to conventional cameras: high temporal resolution,…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Henri Rebecq , René Ranftl , Vladlen Koltun , Davide Scaramuzza

In order to overcome the limitations imposed by DNA barcoding when multiplexing a large number of samples in the current generation of high-throughput sequencing instruments, we have recently proposed a new protocol that leverages advances…

Quantitative Methods · Quantitative Biology 2013-08-02 Denisa Duma , Mary Wootters , Anna C. Gilbert , Hung Q. Ngo , Atri Rudra , Matthew Alpert , Timothy J. Close , Gianfranco Ciardo , Stefano Lonardi

Since the arrival of next-generation sequencing technologies the amount of genetic sequencing data has increased dramatically. This has has fueled an increase in human genetics research. At the same time, with the recent advent of…

Genomics · Quantitative Biology 2016-07-04 Kristiina Ausmees , Pushpam Aji John

Generative models can produce synthetic patient records for analytical tasks when real data is unavailable or limited. However, current methods struggle with adhering to domain-specific knowledge and removing invalid data. We present…

Machine Learning · Computer Science 2023-12-22 Brandon Theodorou , Shrusti Jain , Cao Xiao , Jimeng Sun

Early literature on genome rearrangement modelling views the problem of computing evolutionary distances as an inherently combinatorial one. In particular, attention was given to estimating distances using the minimum number of events…

Populations and Evolution · Quantitative Biology 2023-01-12 Joshua Stevenson , Venta Terauds , Jeremy Sumner

DNA is an attractive medium for digital data storage. When data is stored on DNA, errors occur, which makes error-correcting coding techniques critical for reliable DNA data storage. To reduce the errors, a common technique is to include…

Information Theory · Computer Science 2024-06-27 Franziska Weindel , Andreas L. Gimpel , Robert N. Grass , Reinhard Heckel
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