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Aberrations and multiple scattering in biological tissues critically distort light beams into highly complex speckle patterns. In this regard, digital optical phase conjugation (DOPC) is a promising technique enabling in-depth focusing.…

A two-step detection strategy is suggested for the precise measurement of the optical phase-shift. In the first step an unsharp, however, unbiased joint measurement of the phase and photon number is performed by heterodyning the signal…

Quantum Physics · Physics 2009-10-31 A. V. Chizhov , V. De Renzi , M. G. A. Paris

Ultra-fast and multi-dimensional spectroscopy gives a powerful looking glass into the dynamics of molecular systems. In particular two-dimensional electronic spectroscopy (2DES) provides a probe of coherence and the flow of energy within…

Quantum Physics · Physics 2021-03-31 André Anda , Jared H. Cole

Machine learning is attracting surging interest across nearly all scientific areas by enabling the analysis of large datasets and the extraction of scientific information from incomplete data. Data-driven science is rapidly growing,…

Applied Physics · Physics 2025-03-17 Sung Yun Lee , Do Hyung Cho , Chulho Jung , Daeho Sung , Daewoong Nam , Sangsoo Kim , Changyong Song

By applying a phase-modulation fluorescence approach to 2D electronic spectroscopy, we studied the conformation-dependent exciton-coupling of a porphyrin dimer embedded in a phospholipid bilayer membrane. Our measurements specify the…

Precise measurements of the frequency and phase of an electrical or optical signal play a key role in various branches of science and engineering. Tracking changing laser frequencies is especially demanding when the lasers themselves are…

Instrumentation and Detectors · Physics 2024-12-30 Shreevathsa Chalathadka Subrahmanya , Christian Darsow-Fromm , Oliver Gerberding

Change detection in remote sensing imagery plays a vital role in various engineering applications, such as natural disaster monitoring, urban expansion tracking, and infrastructure management. Despite the remarkable progress of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Xiaoyang Zhang , Guodong Fan , Guang-Yong Chen , Zhen Hua , Jinjiang Li , Min Gan , C. L. Philip Chen

Phase retrieval in optical imaging refers to the recovery of a complex signal from phaseless data acquired in the form of its diffraction patterns. These patterns are acquired through a system with a coherent light source that employs a…

Photomixing of two near-infrared lasers is well established for continuous-wave terahertz spectroscopy. Photomixing of three lasers allows us to measure at three terahertz frequencies simultaneously. Similar to Fourier spectroscopy, the…

Single-molecule fluorescence spectroscopy is a powerful method that avoids ensemble averaging, but its temporal resolution is limited by the fluorescence lifetime to nanoseconds at most. At the ensemble level, two-dimensional spectroscopy…

Optics · Physics 2024-10-11 Sanchayeeta Jana , Simon Durst , Markus Lippitz

Femtosecond interferometry combined with acousto-optical phase modulation is an effective approach to implement various types of coherent nonlinear and multidimensional spectroscopy schemes. The high sensitivity of this method has recently…

Atomic Physics · Physics 2025-02-24 Friedemann Landmesser , Nicolai Gölz , Ulrich Bangert , Tobias Sixt , Lukas Bruder

The investigation of coherent phenomena in strong-field processes requires interferometric measurement schemes with high selectivity to disentangle the complex nonlinear response of the system. Interferometers combining acousto-optical…

The authors demonstrate a form of two-photon-counting interferometry by measuring the coincidence counts between single-photon-counting detectors at an output port of a Mach-Zehnder Interferometer (MZI) following injection of broad-band…

We demonstrate a lock-in particle tracking scheme in optical tweezers based on stroboscopic modulation of an illuminating optical field. This scheme is found to evade low frequency noise sources while otherwise producing an equivalent…

Optics · Physics 2014-09-04 Michael A Taylor , Joachim Knittel , Warwick P Bowen

Vapour cell spectroscopy is an essential technique in many fields; in particular, nearly all atom and ion trapping experiments rely on simultaneous spectroscopy of two atomic transitions, traditionally employing separate apparatus for each…

We demonstrate two-step phase-shifting interferometry (holography) of complex laser modes generated by a spatial light modulator (SLM), in which the amplitude and phase of the signal are determined directly from measurements of…

Optics · Physics 2024-09-16 Lark E. Bradsby , Andrew A. Voitiv , Mark E. Siemens

We present calculations of the fluorescence-detected coherent two-dimensional (F-2DES) spectra of a molecular heterodimer. We compare how the F-2DES technique differs from the standard coherently detected two-dimensional (2DES) spectroscopy…

Chemical Physics · Physics 2018-07-16 Pavel Malý , Tomáš Mančal

Event-based image sensors provide microsecond temporal resolution but lack spectral discrimination, whereas diffractive spectral imagers encode wavelength information at conventional frame rates. We introduce a fluorescence microscopy…

Optics · Physics 2026-03-20 Richard G. Baird , Boyden Myers , Erik M. Jorgensen , Rajesh Menon

Quantum sensors based on atom interferometers are advancing both fundamental physics and practical applications, with higher sensitivity being a key requirement for these investigations. Here, we experimentally demonstrate a sensitivity…

Atomic Physics · Physics 2025-07-01 Sotatsu Otabe , Naoki Kaku , Tomoya Sato , Martin Miranda , Takuya Kawasaki , Mikio Kozuma

We present a dual color laser scanning endomicroscope capable of fluorescence lifetime endomicroscopy at one frame per second (FPS). The scanning system uses a coherent imaging fiber with 30,000 cores. High-speed lifetime imaging is…