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Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Quantitative analysis of brain tumors is critical for clinical decision making. While manual segmentation is tedious, time consuming and subjective, this task is at the same time very challenging to solve for automatic segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2018-03-01 Fabian Isensee , Philipp Kickingereder , Wolfgang Wick , Martin Bendszus , Klaus H. Maier-Hein

The accurate segmentation of brain tumors from multi-modal MRI is critical for clinical diagnosis and treatment planning. While integrating complementary information from various MRI sequences is a common practice, the frequent absence of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Dongqing Xie , Yonghuang Wu , Zisheng Ai , Jun Min , Zhencun Jiang , Shaojin Geng , Lei Wang

Gliomas are one of the most prevalent types of primary brain tumours, accounting for more than 30\% of all cases and they develop from the glial stem or progenitor cells. In theory, the majority of brain tumours could well be identified…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Reza Azad , Nika Khosravi , Dorit Merhof

Deep learning-based brain tumor segmentation (BTS) models for multi-modal MRI images have seen significant advancements in recent years. However, a common problem in practice is the unavailability of some modalities due to varying scanning…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Weide Liu , Jingwen Hou , Xiaoyang Zhong , Huijing Zhan , Jun Cheng , Yuming Fang , Guanghui Yue

Brain tumor segmentation is a fundamental step in assessing a patient's cancer progression. However, manual segmentation demands significant expert time to identify tumors in 3D multimodal brain MRI scans accurately. This reliance on manual…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Fadillah Maani , Anees Ur Rehman Hashmi , Numan Saeed , Mohammad Yaqub

Background: Brain tumor segmentation has a significant impact on the diagnosis and treatment of brain tumors. Accurate brain tumor segmentation remains challenging due to their irregular shapes, vague boundaries, and high variability.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Zhanyuan Jia , Ni Yao , Danyang Sun , Chuang Han , Yanting Li , Jiaofen Nan , Fubao Zhu , Chen Zhao , Weihua Zhou

In clinical practice, the robustness of deep learning models for multimodal brain tumor segmentation is severely compromised by incomplete MRI data. This vulnerability stems primarily from modality bias, where models exploit spurious…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Bo Liu , Yulong Zou , Jin Hong

In this work, we propose a multi-modal Convolutional Neural Network (CNN) approach for brain tumor segmentation. We investigate how to combine different modalities efficiently in the CNN framework.We adapt various fusion methods, which are…

Computer Vision and Pattern Recognition · Computer Science 2018-09-21 Mehmet Aygün , Yusuf Hüseyin Şahin , Gözde Ünal

Accurate brain tumor segmentation using multiparametric MRI is critical for effective treatment planning. However, in clinical settings, complete acquisition of all MRI sequences is not always possible. The absence of certain MRI modalities…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Danish Ali , Ajmal Mian , Naveed Akhtar , Ghulam Mubashar Hassan

Accurate brain tumor segmentation from Magnetic Resonance Imaging (MRI) is desirable to joint learning of multimodal images. However, in clinical practice, it is not always possible to acquire a complete set of MRIs, and the problem of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-05 Yao Zhang , Nanjun He , Jiawei Yang , Yuexiang Li , Dong Wei , Yawen Huang , Yang Zhang , Zhiqiang He , Yefeng Zheng

Brain tumors are one of the deadliest forms of cancer with a mortality rate of over 80%. A quick and accurate diagnosis is crucial to increase the chance of survival. However, in medical analysis, the manual annotation and segmentation of a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Zachary Schwehr , Sriman Achanta

The magnetic resonance (MR) analysis of brain tumors is widely used for diagnosis and examination of tumor subregions. The overlapping area among the intensity distribution of healthy, enhancing, non-enhancing, and edema regions makes the…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Manual brain tumor segmentation from MRI scans is challenging due to tumor heterogeneity, scarcity of annotated data, and class imbalance in medical imaging datasets. Synthetic data generated by generative models has the potential to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Aditi Jahagirdar , Sameer Joshi

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

This work introduces a novel framework for brain tumor segmentation leveraging pre-trained GANs and Unet architectures. By combining a global anomaly detection module with a refined mask generation network, the proposed model accurately…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Qifei Cui , Xinyu Lu

Gliomas are brain tumors composed of different highly heterogeneous histological subregions. Image analysis techniques to identify relevant tumor substructures have high potential for improving patient diagnosis, treatment and prognosis.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 José Gerardo Suárez-García Javier Miguel Hernández-López , Eduardo Moreno-Barbosa , Benito de Celis-Alonso

Multimodal MRI is essential for brain tumor segmentation, yet missing modalities in clinical practice cause existing methods to exhibit >40% performance variance across modality combinations, rendering them clinically unreliable. We propose…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Chengxiang Guo , Jian Wang , Junhua Fei , Xiao Li , Chunling Chen , Yun Jin

Missing data is a common problem in machine learning and in retrospective imaging research it is often encountered in the form of missing imaging modalities. We propose to take into account missing modalities in the design and training of…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Karin van Garderen , Marion Smits , Stefan Klein