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The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…
The ability to explain the prediction of deep learning models to end-users is an important feature to leverage the power of artificial intelligence (AI) for the medical decision-making process, which is usually considered non-transparent…
Stochastic processes provide a mathematically elegant way model complex data. In theory, they provide flexible priors over function classes that can encode a wide range of interesting assumptions. In practice, however, efficient inference…
Variational autoencoders (VAEs) are widely used deep generative models capable of learning unsupervised latent representations of data. Such representations are often difficult to interpret or control. We consider the problem of…
Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…
Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…
Framing the investigation of diverse cancers as a machine learning problem has recently shown significant potential in multi-omics analysis and cancer research. Empowering these successful machine learning models are the high-quality…
In this tutorial, we explore Variational Autoencoders (VAEs), an essential framework for unsupervised learning, particularly suited for high-dimensional datasets such as neuroimaging. By integrating deep learning with Bayesian inference,…
Learning compact and interpretable representations of data is a critical challenge in scientific image analysis. Here, we introduce Affinity-VAE, a generative model that enables us to impose our scientific intuition about the similarity of…
The need for interpretable models has fostered the development of self-explainable classifiers. Prior approaches are either based on multi-stage optimization schemes, impacting the predictive performance of the model, or produce…
The extensive utilization of biometric authentication systems have emanated attackers / imposters to forge user identity based on morphed images. In this attack, a synthetic image is produced and merged with genuine. Next, the resultant…
As machine learning systems increasingly inform critical decisions, the need for human-understandable explanations grows. Current evaluations of Explainable AI (XAI) often prioritize technical fidelity over cognitive accessibility which…
Many Machine Learning algorithms, such as deep neural networks, have long been criticized for being "black-boxes"-a kind of models unable to provide how it arrive at a decision without further efforts to interpret. This problem has raised…
Learning interpretable representations of data remains a central challenge in deep learning. When training a deep generative model, the observed data are often associated with certain categorical labels, and, in parallel with learning to…
Black-box nature of Artificial Intelligence (AI) models do not allow users to comprehend and sometimes trust the output created by such model. In AI applications, where not only the results but also the decision paths to the results are…
The characterization of Tumor MicroEnvironment (TME) is challenging due to its complexity and heterogeneity. Relatively consistent TME characteristics embedded within highly specific tissue features, render them difficult to predict. The…
Developing computational tools for integrative analysis across multiple types of omics data has been of immense importance in cancer molecular biology and precision medicine research. While recent advancements have yielded integrative…
Interpretable machine learning is rapidly becoming a crucial tool for scientific discovery. Among existing approaches, variational autoencoders (VAEs) have shown promise in extracting the hidden physical features of some input data, with no…
Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…
Explainable artificial intelligence (XAI) aims to develop transparent explanatory approaches for "black-box" deep learning models. However,it remains difficult for existing methods to achieve the trade-off of the three key criteria in…