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Virtual staining is a promising technique that uses deep generative models to recreate histological stains, providing a faster and more cost-effective alternative to traditional tissue chemical staining. Specifically for H&E-HER2 staining…

Image and Video Processing · Electrical Eng. & Systems 2025-10-02 Pascal Klöckner , José Teixeira , Diana Montezuma , Jaime S. Cardoso , Hugo M. Horlings , Sara P. Oliveira

Generative Adversarial Networks (GANs) have become increasingly powerful, generating mind-blowing photorealistic images that mimic the content of datasets they were trained to replicate. One recurrent theme in medical imaging is whether…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Youssef Skandarani , Pierre-Marc Jodoin , Alain Lalande

Generative adversarial networks (GANs) have remarkably advanced in diverse domains, especially image generation and editing. However, the misuse of GANs for generating deceptive images, such as face replacement, raises significant security…

Computer Vision and Pattern Recognition · Computer Science 2024-01-31 Lei Zhang , Hao Chen , Shu Hu , Bin Zhu , Ching Sheng Lin , Xi Wu , Jinrong Hu , Xin Wang

Transfer learning makes it possible to use large vision networks on a variety of domains, by specializing their models' general filters to new tasks. However, these networks assume the input images to have 3 input channels, making them…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Mariette Schönfeld , Laurens Devos , Wannes Meert , Hendrik Blockeel

In this paper, we develop a complete pipeline for stain normalization, segmentation, and classification of nuclei in hematoxylin and eosin (H&E) stained breast cancer histopathology images. In the first step, we use a CNN-based stain…

Computer Vision and Pattern Recognition · Computer Science 2018-11-12 Edwin Yuan , Junkyo Suh

The growing use of Machine Learning has produced significant advances in many fields. For image-based tasks, however, the use of deep learning remains challenging in small datasets. In this article, we review, evaluate and compare the…

Machine Learning · Computer Science 2021-06-09 Miguel Romero , Yannet Interian , Timothy Solberg , Gilmer Valdes

Most deep learning models are data-driven and the excellent performance is highly dependent on the abundant and diverse datasets. However, it is very hard to obtain and label the datasets of some specific scenes or applications. If we train…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Tianxiao Zhang , Wenchi Ma , Guanghui Wang

Domain shift between medical images from multicentres is still an open question for the community, which degrades the generalization performance of deep learning models. Generative adversarial network (GAN), which synthesize plausible…

Image and Video Processing · Electrical Eng. & Systems 2020-07-31 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Generative models, such as GANs, learn an explicit low-dimensional representation of a particular class of images, and so they may be used as natural image priors for solving inverse problems such as image restoration and compressive…

Machine Learning · Computer Science 2025-10-28 Mara Daniels , Paul Hand , Reinhard Heckel

As interest in applying machine learning techniques for medical images continues to grow at a rapid pace, models are starting to be developed and deployed for clinical applications. In the clinical AI model development lifecycle (described…

Image and Video Processing · Electrical Eng. & Systems 2020-08-20 Giorgio Pietro Biondetti , Romane Gauriau , Christopher P. Bridge , Charles Lu , Katherine P. Andriole

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

Deep learning has achieved great success in the challenging circuit annotation task by employing Convolutional Neural Networks (CNN) for the segmentation of circuit structures. The deep learning approaches require a large amount of manually…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Yee-Yang Tee , Deruo Cheng , Chye-Soon Chee , Tong Lin , Yiqiong Shi , Bah-Hwee Gwee

Although numerous improvements have been made in the field of image segmentation using convolutional neural networks, the majority of these improvements rely on training with larger datasets, model architecture modifications, novel loss…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Saied Asgari Taghanaki , Kumar Abhishek , Ghassan Hamarneh

This study introduces an innovative application of Conditional Generative Adversarial Networks (C-GAN) integrated with Stacked Hourglass Networks (SHGN) aimed at enhancing image segmentation, particularly in the challenging environment of…

Image and Video Processing · Electrical Eng. & Systems 2024-08-06 Haowei Yang , Yuxiang Hu , Shuyao He , Ting Xu , Jiajie Yuan , Xingxin Gu

Deep learning has been extensively used in medical imaging applications, assuming that the test and training datasets belong to the same probability distribution. However, a common challenge arises when working with medical images generated…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Mohd Usama , Belal Ahmad , Christer Gronlund , Faleh Menawer R Althiyabi

Bayesian inference for inverse problems hinges critically on the choice of priors. In the absence of specific prior information, population-level distributions can serve as effective priors for parameters of interest. With the advent of…

Instrumentation and Methods for Astrophysics · Physics 2025-02-11 Gabriel Missael Barco , Alexandre Adam , Connor Stone , Yashar Hezaveh , Laurence Perreault-Levasseur

Lack of annotated samples greatly restrains the direct application of deep learning in remote sensing image scene classification. Although researches have been done to tackle this issue by data augmentation with various image transformation…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Dongao Ma , Ping Tang , Lijun Zhao

Currently, image generation and synthesis have remarkably progressed with generative models. Despite photo-realistic results, intrinsic discrepancies are still observed in the frequency domain. The spectral discrepancy appeared not only in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Seokjun Lee , Seung-Won Jung , Hyunseok Seo

Pathological diagnosis relies on the visual inspection of histologically stained thin tissue specimens, where different types of stains are applied to bring contrast to and highlight various desired histological features. However, the…

Medical Physics · Physics 2022-08-18 Xilin Yang , Bijie Bai , Yijie Zhang , Yuzhu Li , Kevin de Haan , Tairan Liu , Aydogan Ozcan

Transfer learning from supervised ImageNet models has been frequently used in medical image analysis. Yet, no large-scale evaluation has been conducted to benchmark the efficacy of newly-developed pre-training techniques for medical image…

Computer Vision and Pattern Recognition · Computer Science 2021-08-16 Mohammad Reza Hosseinzadeh Taher , Fatemeh Haghighi , Ruibin Feng , Michael B. Gotway , Jianming Liang