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Gleason grading specified in ISUP 2014 is the clinical standard in staging prostate cancer and the most important part of the treatment decision. However, the grading is subjective and suffers from high intra and inter-user variability. To…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Nikolay Burlutskiy , Nicolas Pinchaud , Feng Gu , Daniel Hägg , Mats Andersson , Lars Björk , Kristian Eurén , Cristina Svensson , Lena Kajland Wilén , Martin Hedlund

Oral cancer ranks among the most prevalent cancers globally, with a particularly high mortality rate in regions lacking adequate healthcare access. Early diagnosis is crucial for reducing mortality; however, challenges persist due to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Akshay Bhagwan Sonawane , Lena D. Swamikannan , Lakshman Tamil

The segmentation and automatic identification of histological regions of diagnostic interest offer a valuable aid to pathologists. However, segmentation methods are hampered by the difficulty of obtaining pixel-level annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Pushpak Pati , Guillaume Jaume , Zeineb Ayadi , Kevin Thandiackal , Behzad Bozorgtabar , Maria Gabrani , Orcun Goksel

In this work, we propose a deep U-Net based model to tackle the challenging task of prostate cancer segmentation by aggressiveness in MRI based on weak scribble annotations. This model extends the size constraint loss proposed by Kervadec…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Audrey Duran , Gaspard Dussert , Carole Lartizien

Automatic segmentation of medical images with DL algorithms has proven to be highly successful. With most of these algorithms, inter-observer variation is an acknowledged problem, leading to sub-optimal results. This problem is even more…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Anjali Balagopal , Howard Morgan , Michael Dohopoloski , Ramsey Timmerman , Jie Shan , Daniel F. Heitjan , Wei Liu , Dan Nguyen , Raquibul Hannan , Aurelie Garant , Neil Desai , Steve Jiang

Celiac disease prevalence and diagnosis have increased substantially in recent years. The current gold standard for celiac disease confirmation is visual examination of duodenal mucosal biopsies. An accurate computer-aided biopsy analysis…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Jerry W. Wei , Christopher R. Jackson , Bing Ren , Arief A. Suriawinata , Saeed Hassanpour

Prostate cancer is the most common cancer among US men. However, prostate imaging is still challenging despite the advances in multi-parametric Magnetic Resonance Imaging (MRI), which provides both morphologic and functional information…

While microscopic analysis of histopathological slides is generally considered as the gold standard method for performing cancer diagnosis and grading, the current method for analysis is extremely time consuming and labour intensive as it…

Computer Vision and Pattern Recognition · Computer Science 2018-06-25 Rene Bidart , Alexander Wong

Using deep learning models to diagnose cancer from histology data presents several challenges. Cancer grading and localization of regions of interest (ROIs) in these images normally relies on both image- and pixel-level labels, the latter…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Jérôme Rony , Soufiane Belharbi , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

With the development of computational pathology, deep learning methods for Gleason grading through whole slide images (WSIs) have excellent prospects. Since the size of WSIs is extremely large, the image label usually contains only…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Hao Bian , Zhuchen Shao , Yang Chen , Yifeng Wang , Haoqian Wang , Jian Zhang , Yongbing Zhang

Throughout the world, breast cancer is one of the leading causes of female death. Recently, deep learning methods are developed to automatically grade breast cancer of histological slides. However, the performance of existing deep learning…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Yanyuet Man , Xiangyun Ding , Xingcheng Yao , Han Bao

Cervical cancer is a crucial global health concern for women, and the persistent infection of High-risk HPV mainly triggers this remains a global health challenge, with young women diagnosis rates soaring from 10\% to 40\% over three…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Tatsuhiro Baba , Abu Saleh Musa Miah , Jungpil Shin , Md. Al Mehedi Hasan

Traditional CNN models are trained and tested on relatively low resolution images (<300 px), and cannot be directly operated on large-scale images due to compute and memory constraints. We propose Patch Gradient Descent (PatchGD), an…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Deepak K. Gupta , Gowreesh Mago , Arnav Chavan , Dilip K. Prasad

Northern Europe has the second highest mortality rate of melanoma globally. In 2020, the mortality rate of melanoma rose to 1.9 per 100 000 habitants. Melanoma prognosis is based on a pathologist's subjective visual analysis of the…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Christopher Andreassen , Saul Fuster , Helga Hardardottir , Emiel A. M. Janssen , Kjersti Engan

Weakly supervised learning has been rapidly advanced in biomedical image analysis to achieve pixel-wise labels (segmentation) from image-wise annotations (classification), as biomedical images naturally contain image-wise labels in many…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Ruining Deng , Quan Liu , Shunxing Bao , Aadarsh Jha , Catie Chang , Bryan A. Millis , Matthew J. Tyska , Yuankai Huo

With the increase in the number of image data and the lack of corresponding labels, weakly supervised learning has drawn a lot of attention recently in computer vision tasks, especially in the fine-grained semantic segmentation problem. To…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Ke Zhang , Sihong Chen , Qi Ju , Yong Jiang , Yucong Li , Xin He

Supervised deep learning-based methods yield accurate results for medical image segmentation. However, they require large labeled datasets for this, and obtaining them is a laborious task that requires clinical expertise.…

Computer Vision and Pattern Recognition · Computer Science 2021-12-20 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

The diagnosis of prostate cancer faces a problem with overdiagnosis that leads to damaging side effects due to unnecessary treatment. Research has shown that the use of multi-parametric magnetic resonance images to conduct biopsies can…

Image and Video Processing · Electrical Eng. & Systems 2021-06-04 Pedro C. Neto

Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Laura J. Tafe , Yevgeniy A. Linnik , Louis J. Vaickus , Naofumi Tomita , Saeed Hassanpour

Automated skin lesion classification using deep learning has shown remarkable accuracy, yet clinical adoption remains limited due to the "black box" nature of these models. We present MelanomaNet, an explainable deep learning system for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Sukhrobbek Ilyosbekov