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Revealing the functional sites of biological sequences, such as evolutionary conserved, structurally interacting or co-evolving protein sites, is a fundamental, and yet challenging task. Different frameworks and models were developed to…

Quantitative Methods · Quantitative Biology 2019-06-07 Justas Dauparas , Haobo Wang , Avi Swartz , Peter Koo , Mor Nitzan , Sergey Ovchinnikov

Deep networks for image classification often rely more on texture information than object shape. While efforts have been made to make deep-models shape-aware, it is often difficult to make such models simple, interpretable, or rooted in…

Computer Vision and Pattern Recognition · Computer Science 2023-05-24 Rajhans Singh , Ankita Shukla , Pavan Turaga

Networks are complex models for underlying data in many application domains. In most instances, raw data is not natively in the form of a network, but derived from sensors, logs, images, or other data. Yet, the impact of the various choices…

Social and Information Networks · Computer Science 2020-04-07 Ivan Brugere , Tanya Y. Berger-Wolf

We take inspiration from the study of human explanation to inform the design and evaluation of interpretability methods in machine learning. First, we survey the literature on human explanation in philosophy, cognitive science, and the…

Artificial Intelligence · Computer Science 2021-09-21 David Alvarez-Melis , Harmanpreet Kaur , Hal Daumé , Hanna Wallach , Jennifer Wortman Vaughan

Ensuring transparency in AI decision-making requires interpretable explanations, particularly at the instance level. Counterfactual explanations are a powerful tool for this purpose, but existing techniques frequently depend on synthetic…

Machine Learning · Computer Science 2025-02-13 Minh Hieu Nguyen , Viet Hung Doan , Anh Tuan Nguyen , Jun Jo , Quoc Viet Hung Nguyen

In federated learning, differences in the data or objectives between the participating nodes motivate approaches to train a personalized machine learning model for each node. One such approach is weighted averaging between a locally trained…

Machine Learning · Computer Science 2021-10-26 Felix Grimberg , Mary-Anne Hartley , Sai P. Karimireddy , Martin Jaggi

Neural models learn data representations that lie on low-dimensional manifolds, yet modeling the relation between these representational spaces is an ongoing challenge. By integrating spectral geometry principles into neural modeling, we…

Machine Learning · Computer Science 2025-07-15 Marco Fumero , Marco Pegoraro , Valentino Maiorca , Francesco Locatello , Emanuele Rodolà

In social science, formal and quantitative models, such as ones describing economic growth and collective action, are used to formulate mechanistic explanations, provide predictions, and uncover questions about observed phenomena. Here, we…

Symbolic Computation · Computer Science 2023-08-17 Julia Balla , Sihao Huang , Owen Dugan , Rumen Dangovski , Marin Soljacic

It is known that, without awareness of the process, our brain appears to focus on the general shape of objects rather than superficial statistics of context. On the other hand, learning autonomously allows discovering invariant regularities…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Nader Asadi , Amir M. Sarfi , Mehrdad Hosseinzadeh , Zahra Karimpour , Mahdi Eftekhari

Spatial documentation is exponentially increasing given the availability of Big IoT Data, enabled by the devices miniaturization and data storage capacity. Bayesian spatial statistics is a useful statistical tool to determine the dependence…

Methodology · Statistics 2020-10-01 Francisco Louzada , Diego C. Nascimento , Osafu Augustine Egbon

In this work, we propose ModelPred, a framework that helps to understand the impact of changes in training data on a trained model. This is critical for building trust in various stages of a machine learning pipeline: from cleaning…

Machine Learning · Computer Science 2022-12-27 Yingyan Zeng , Jiachen T. Wang , Si Chen , Hoang Anh Just , Ran Jin , Ruoxi Jia

Feature Learning aims to extract relevant information contained in data sets in an automated fashion. It is driving force behind the current deep learning trend, a set of methods that have had widespread empirical success. What is lacking…

Machine Learning · Statistics 2015-04-02 Brendan van Rooyen , Robert C. Williamson

There are many issues that can cause problems when attempting to infer model parameters from data. Data and models are both imperfect, and as such there are multiple scenarios in which standard methods of inference will lead to misleading…

Computation · Statistics 2024-05-01 Simon L. Cotter

Recent advancements in semi-supervised deep learning have introduced effective strategies for leveraging both labeled and unlabeled data to improve classification performance. This work proposes a semi-supervised framework that utilizes a…

Machine Learning · Computer Science 2025-05-21 Aydin Abedinia , Shima Tabakhi , Vahid Seydi

Interpretation and explanation of deep models is critical towards wide adoption of systems that rely on them. In this paper, we propose a novel scheme for both interpretation as well as explanation in which, given a pretrained model, we…

Computer Vision and Pattern Recognition · Computer Science 2019-03-11 Jose Oramas , Kaili Wang , Tinne Tuytelaars

Interpretable classification models are built with the purpose of providing a comprehensible description of the decision logic to an external oversight agent. When considered in isolation, a decision tree, a set of classification rules, or…

Machine Learning · Computer Science 2019-03-18 Riccardo Guidotti , Salvatore Ruggieri

Modern vision models achieve remarkable accuracy, but explaining where evidence arises, what the model encodes, and how internal computations assemble that evidence remains fragmented. We introduce an iERF-centric framework that unifies…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Yearim Kim , Sangyu Han , Nojun Kwak

Differential equations are a ubiquitous tool to study dynamics, ranging from physical systems to complex systems, where a large number of agents interact through a graph with non-trivial topological features. Data-driven approximations of…

Statistical Mechanics · Physics 2024-04-26 Vaiva Vasiliauskaite , Nino Antulov-Fantulin

Modeling environmental ecosystems is essential for effective resource management, sustainable development, and understanding complex ecological processes. However, traditional methods frequently struggle with the inherent complexity,…

Machine Learning · Computer Science 2025-03-06 Runlong Yu , Shengyu Chen , Yiqun Xie , Xiaowei Jia

Forensic examination of evidence like firearms and toolmarks, traditionally involves a visual and therefore subjective assessment of similarity of two questioned items. Statistical models are used to overcome this subjectivity and allow…

Human-Computer Interaction · Computer Science 2021-11-03 Ganesh Krishnan , Heike Hofmann