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Bayesian computational algorithms tend to scale poorly as data size increases. This has motivated divide-and-conquer-based approaches for scalable inference. These divide the data into subsets, perform inference for each subset in parallel,…

Methodology · Statistics 2025-10-22 Rihui Ou , Lachlan Astfalck , Deborshee Sen , David Dunson

Dynamic treatment regimes (DTRs) formalize medical decision-making as a sequence of rules for different stages, mapping patient-level information to recommended treatments. In practice, estimating an optimal DTR using observational data…

Methodology · Statistics 2024-12-11 Jian Sun , Bo Fu , Li Su

Bayesian methods hold significant promise for improving the uncertainty quantification ability and robustness of deep neural network models. Recent research has seen the investigation of a number of approximate Bayesian inference methods…

Machine Learning · Computer Science 2022-02-09 Meet P. Vadera , Adam D. Cobb , Brian Jalaian , Benjamin M. Marlin

High-dimensional malware datasets often exhibit feature redundancy, instability, and scalability limitations, which hinder the effectiveness and interpretability of machine learning-based malware detection systems. Although feature…

Cryptography and Security · Computer Science 2026-01-23 Ajvad Haneef K , Karan Kuwar Singh , Madhu Kumar S D

Reading is foundational for educational, employment, and economic outcomes, but a persistent proportion of students globally struggle to develop adequate reading skills. Some countries promote digital tools to support reading development,…

Applications · Statistics 2026-03-19 Yawen Ma , Anastasia Ushakova , Kate Cain , Gabriel Wallin

While deep learning methods continue to improve in predictive accuracy on a wide range of application domains, significant issues remain with other aspects of their performance including their ability to quantify uncertainty and their…

Machine Learning · Computer Science 2020-07-10 Meet P. Vadera , Adam D. Cobb , Brian Jalaian , Benjamin M. Marlin

Boosting methods are widely used in statistical learning to deal with high-dimensional data due to their variable selection feature. However, those methods lack straightforward ways to construct estimators for the precision of the…

Methodology · Statistics 2021-06-10 Boyao Zhang , Colin Griesbach , Cora Kim , Nadia Müller-Voggel , Elisabeth Bergherr

Dynamic Causal Modeling (DCM) is a Bayesian framework for inferring on hidden (latent) neuronal states, based on measurements of brain activity. Since its introduction in 2003 for functional magnetic resonance imaging data, DCM has been…

Quantitative Methods · Quantitative Biology 2021-04-08 Inês Pereira , Stefan Frässle , Jakob Heinzle , Dario Schöbi , Cao Tri Do , Moritz Gruber , Klaas E. Stephan

A major practical impediment when implementing adaptive dose-finding designs is that the toxicity outcome used by the decision rules may not be observed shortly after the initiation of the treatment. To address this issue, we propose the…

Applications · Statistics 2014-01-09 Suyu Liu , Guosheng Yin , Ying Yuan

Objective: Estimation of the global optima of multiple model parameters is valuable in imaging to form a reliable diagnostic image. Given non convexity of the objective function, it is challenging to avoid from different local minima.…

Machine Learning · Computer Science 2022-04-06 Hongmei Zhang , Kai Wang , Yan Zhou , Shadab Momin , Xiaofeng Yang , Mostafa Fatemi , Michael F. Insana

The stochastic block model (SBM) is a generative model revealing macroscopic structures in graphs. Bayesian methods are used for (i) cluster assignment inference and (ii) model selection for the number of clusters. In this paper, we study…

Machine Learning · Computer Science 2016-02-09 Kohei Hayashi , Takuya Konishi , Tatsuro Kawamoto

Single-cell RNA sequencing allows the quantification of gene expression at the individual cell level, enabling the study of cellular heterogeneity and gene expression dynamics. Dimensionality reduction is a common preprocessing step…

Computation · Statistics 2025-10-14 Cristian Castiglione , Alexandre Segers , Lieven Clement , Davide Risso

Pseudospectral analysis is fundamental for quantifying the sensitivity and transient behavior of nonnormal matrices, yet its computational cost scales cubically with dimension, rendering it prohibitive for large-scale systems. While…

Numerical Analysis · Mathematics 2026-02-03 Vladimir R. Kostic , Dragana Lj. Cvetkovic , Ljiljana Cvetkovic

Compressing large-scale neural networks is essential for deploying models on resource-constrained devices. Most existing methods adopt weight pruning or low-bit quantization individually, often resulting in suboptimal compression rates to…

Machine Learning · Computer Science 2025-10-13 Ziyi Wang , Nan Jiang , Guang Lin , Qifan Song

In genomics, differential abundance and expression analyses are complicated by the compositional nature of sequence count data, which reflect only relative-not absolute-abundances or expression levels. Many existing methods attempt to…

Methodology · Statistics 2025-12-16 Won Gu , Francesca Chiaromonte , Justin D. Silverman

This article addresses the problem of efficient Bayesian inference in dynamic systems using particle methods and makes a number of contributions. First, we develop a correlated pseudo-marginal (CPM) approach for Bayesian inference in state…

Methodology · Statistics 2016-12-22 P. Choppala , D. Gunawan , J. Chen , M. -N. Tran , R. Kohn

In this work, a new class of stochastic gradient algorithm is developed based on $q$-calculus. Unlike the existing $q$-LMS algorithm, the proposed approach fully utilizes the concept of $q$-calculus by incorporating time-varying $q$…

Optimization and Control · Mathematics 2018-01-03 Shujaat Khan , Alishba Sadiq , Imran Naseem , Roberto Togneri , Mohammed Bennamoun

Statistical learning additions to physically derived mathematical models are gaining traction in the literature. A recent approach has been to augment the underlying physics of the governing equations with data driven Bayesian statistical…

Methodology · Statistics 2022-05-25 Connor Duffin , Edward Cripps , Thomas Stemler , Mark Girolami

Structured additive distributional regression models offer a versatile framework for estimating complete conditional distributions by relating all parameters of a parametric distribution to covariates. Although these models efficiently…

Methodology · Statistics 2023-11-14 Jana Kleinemeier , Nadja Klein

This paper presents a strategy for efficient quantum circuit design for density estimation. The strategy is based on a quantum-inspired algorithm for density estimation and a circuit optimisation routine based on memetic algorithms. The…