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Randomized controlled trials (RCTs) are indispensable for establishing the clinical value of medical artificial-intelligence (AI) tools, yet their high cost and long timelines hinder timely validation as new models emerge rapidly. Here, we…

Machine Learning · Computer Science 2025-11-17 Michael Nercessian , Wenxin Zhang , Alexander Schubert , Daphne Yang , Maggie Chung , Ahmed Alaa , Adam Yala

The integration of Artificial Intelligence in the development of computer systems presents a new challenge: make intelligent systems explainable to humans. This is especially vital in the field of health and well-being, where transparency…

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Due to escalating healthcare costs, accurately predicting which patients will incur high costs is an important task for payers and providers of healthcare. High-cost claimants (HiCCs) are patients who have annual costs above $\$250,000$ and…

Artificial intelligence-augmented technology represents a considerable opportunity for improving healthcare delivery. Significant progress has been made to demonstrate the value of complex models to enhance clinicians` efficiency in…

Human-Computer Interaction · Computer Science 2025-04-08 Mohammad Golam Kibria , Lauren Kucirka , Javed Mostafa

Identification of patients at high risk for readmission could help reduce morbidity and mortality as well as healthcare costs. Most of the existing studies on readmission prediction did not compare the contribution of data categories. In…

Quantitative Methods · Quantitative Biology 2018-03-23 Wendong Ge , Hee Yeun Kim , Sonali Desai , Leonid Perlovsky , Alexander Turchin

Outcome prediction from clinical text can prevent doctors from overlooking possible risks and help hospitals to plan capacities. We simulate patients at admission time, when decision support can be especially valuable, and contribute a…

Computation and Language · Computer Science 2021-02-09 Betty van Aken , Jens-Michalis Papaioannou , Manuel Mayrdorfer , Klemens Budde , Felix A. Gers , Alexander Löser

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Hospital readmissions are expensive and reflect the inadequacies in healthcare system. In the United States alone, treatment of readmitted diabetic patients exceeds 250 million dollars per year. Early identification of patients facing a…

Artificial Intelligence · Computer Science 2016-02-16 Malladihalli S Bhuvan , Ankit Kumar , Adil Zafar , Vinith Kishore

Intracerebral hemorrhage (ICH) is a life-risking condition characterized by bleeding within the brain parenchyma. ICU readmission in ICH patients is a critical outcome, reflecting both clinical severity and resource utilization. Accurate…

Machine Learning · Computer Science 2025-01-03 Shuheng Chen , Junyi Fan , Armin Abdollahi , Negin Ashrafi , Kamiar Alaei , Greg Placencia , Maryam Pishgar

In this work we explored building automatic speech recognition models for transcribing doctor patient conversation. We collected a large scale dataset of clinical conversations ($14,000$ hr), designed the task to represent the real word…

Medical tabular data, abundant in Electronic Health Records (EHRs), is a valuable resource for diverse medical tasks such as risk prediction. While deep learning approaches, particularly transformer-based models, have shown remarkable…

Computation and Language · Computer Science 2025-04-11 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

Importance: Emergency department (ED) returns for mental health conditions pose a major healthcare burden, with 24-27% of patients returning within 30 days. Traditional machine learning models for predicting these returns often lack…

Hospitals struggle to predict critical outcomes. Traditional early warning systems, like NEWS and MEWS, rely on static variables and fixed thresholds, limiting their adaptability, accuracy, and personalization. We previously developed the…

Large language models (LLMs) are revolutionizing various domains with their remarkable natural language processing (NLP) abilities. However, deploying LLMs in resource-constrained edge computing and embedded systems presents significant…

Artificial Intelligence · Computer Science 2024-03-05 Abdul Basit , Khizar Hussain , Muhammad Abdullah Hanif , Muhammad Shafique

The integration of voice-based AI agents in healthcare presents a transformative opportunity to bridge economic and accessibility gaps in digital health delivery. This paper explores the role of large language model (LLM)-powered voice…

Artificial Intelligence · Computer Science 2025-07-28 Bo Wen , Chen Wang , Qiwei Han , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Jeffrey L. Rogers

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Readmission following discharge from an initial hospitalization is a key marker of quality of health care in the United States. For the most part, readmission has been used to study quality of care for patients with acute health conditions,…

Applications · Statistics 2017-11-21 Kyu Ha Lee , Francesca Dominici , Deborah Schrag , Sebastien Haneuse
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