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The ability to extrapolate gene expression dynamics in living single cells requires robust cell segmentation, and one of the challenges is the amorphous or irregularly shaped cell boundaries. To address this issue, we modified the U-Net…
Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…
Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main…
This paper presents an effective and general data augmentation framework for medical image segmentation. We adopt a computationally efficient and data-efficient gradient-based meta-learning scheme to explicitly align the distribution of…
Data augmentation is a widely used and effective technique to improve the generalization performance of deep neural networks. Yet, despite often facing limited data availability when working with medical images, it is frequently…
Diabetic retinopathy is the most important complication of diabetes. Early diagnosis of retinal lesions helps to avoid visual loss or blindness. Due to high-resolution and small-size lesion regions, applying existing methods, such as…
Ureteroscopy is becoming the first surgical treatment option for the majority of urinary affections. This procedure is performed using an endoscope which provides the surgeon with the visual information necessary to navigate inside the…
Deep learning models usually require sufficient training data to achieve high accuracy, but obtaining labeled data can be time-consuming and labor-intensive. Here we introduce a template-based training method to train a 3D U-Net model from…
Accurate segmentation of blood vessels is essential for various clinical assessments and postoperative analyses. However, the inherent challenges of vascular imaging, such as sparsity, fine granularity, low contrast, data distribution…
With the rapid development of deep learning, CNN-based U-shaped networks have succeeded in medical image segmentation and are widely applied for various tasks. However, their limitations in capturing global features hinder their performance…
Unpaired image-to-image translation of retinal images can efficiently increase the training dataset for deep-learning-based multi-modal retinal registration methods. Our method integrates a vessel segmentation network into the…
Robot-guided catheter insertion has the potential to deliver urgent medical care in situations where medical personnel are unavailable. However, this technique requires accurate and reliable segmentation of anatomical landmarks in the body.…
Noisy data and the similarity in the ocular appearances caused by different ophthalmic pathologies pose significant challenges for an automated expert system to accurately detect retinal diseases. In addition, the lack of knowledge…
In this work we propose a method for anatomical data augmentation that is based on using slices of computed tomography (CT) examinations that are adjacent to labeled slices as another resource of labeled data for training the network. The…
Clinical screening with low-quality fundus images is challenging and significantly leads to misdiagnosis. This paper addresses the issue of improving the retinal image quality and vessel segmentation through retinal image restoration. More…
Deep learning based models, generally, require a large number of samples for appropriate training, a requirement that is difficult to satisfy in the medical field. This issue can usually be avoided with a proper initialization of the…
We propose a novel deep-learning-based system for vessel segmentation. Existing methods using CNNs have mostly relied on local appearances learned on the regular image grid, without considering the graphical structure of vessel shape. To…
The retinal vasculature provides important clues in the diagnosis and monitoring of systemic diseases including hypertension and diabetes. The microvascular system is of primary involvement in such conditions, and the retina is the only…
Segmentation for tracking surgical instruments plays an important role in robot-assisted surgery. Segmentation of surgical instruments contributes to capturing accurate spatial information for tracking. In this paper, a novel network,…
Purpose: Automatic and accurate segmentation of fundus vessel images has become an essential prerequisite for computer-aided diagnosis of ophthalmic diseases such as diabetes mellitus. The task of high-precision retinal vessel segmentation…