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Mechanical ventilation is a critical life support intervention that delivers controlled air and oxygen to a patient's lungs, assisting or replacing spontaneous breathing. While several data-driven approaches have been proposed to optimize…

Machine Learning · Computer Science 2025-01-10 Joo Seung Lee , Malini Mahendra , Anil Aswani

Mechanical ventilation is a key form of life support for patients with pulmonary impairment. Healthcare workers are required to continuously adjust ventilator settings for each patient, a challenging and time consuming task. Hence, it would…

Machine Learning · Computer Science 2022-10-07 Flemming Kondrup , Thomas Jiralerspong , Elaine Lau , Nathan de Lara , Jacob Shkrob , My Duc Tran , Doina Precup , Sumana Basu

The year 2020 has seen the COVID-19 virus lead to one of the worst global pandemics in history. As a result, governments around the world are faced with the challenge of protecting public health, while keeping the economy running to the…

Machine Learning · Computer Science 2020-10-22 Varun Kompella , Roberto Capobianco , Stacy Jong , Jonathan Browne , Spencer Fox , Lauren Meyers , Peter Wurman , Peter Stone

This work examines the use of reinforcement learning (RL) to optimize cyclic lockdowns, which is one of the methods available for control of the COVID-19 pandemic. The problem is structured as an optimal control system for tracking a…

Machine Learning · Computer Science 2020-09-11 Mauricio Arango , Lyudmil Pelov

As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often…

Machine Learning · Computer Science 2022-06-30 Yuqing Wang , Yun Zhao , Linda Petzold

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned…

This paper presents a real time, data driven decision support framework for epidemic control. We combine a compartmental epidemic model with sequential Bayesian inference and reinforcement learning (RL) controllers that adaptively choose…

Methodology · Statistics 2025-11-25 Giacomo Iannucci , Petros Barmpounakis , Alexandros Beskos , Nikolaos Demiris

We predict mechanical ventilation requirement and mortality using computational modeling of chest radiographs (CXRs) for coronavirus disease 2019 (COVID-19) patients. This two-center, retrospective study analyzed 530 deidentified CXRs from…

Artificial intelligence-based analysis of lung ultrasound imaging has been demonstrated as an effective technique for rapid diagnostic decision support throughout the COVID-19 pandemic. However, such techniques can require days- or…

There has been considerable interest in leveraging RL and stochastic control methods to learn optimal treatment strategies for critically ill patients, directly from observational data. However, there is significant ambiguity on the control…

Machine Learning · Computer Science 2022-07-21 Thesath Nanayakkara

Background: Providing appropriate care for people suffering from COVID-19, the disease caused by the pandemic SARS-CoV-2 virus is a significant global challenge. Many individuals who become infected have pre-existing conditions that may…

During the coronavirus disease 2019 (COVID-19) pandemic, rapid and accurate triage of patients at the emergency department is critical to inform decision-making. We propose a data-driven approach for automatic prediction of deterioration…

Invasive mechanical ventilation (MV) is a life-sustaining therapy commonly used in the intensive care unit (ICU) for patients with severe and acute conditions. These patients frequently rely on MV for breathing. Given the high risk of death…

Machine Learning · Computer Science 2026-01-16 Muhammad Hamza Yousuf , Jason Li , Sahar Vahdati , Raphael Theilen , Jakob Wittenstein , Jens Lehmann

Our aim is to establish a framework where reinforcement learning (RL) of optimizing interventions retrospectively allows us a regulatory compliant pathway to prospective clinical testing of the learned policies in a clinical deployment. We…

Machine Learning · Computer Science 2020-03-20 Luchen Li , Ignacio Albert-Smet , Aldo A. Faisal

Dental disease is one of the most common chronic diseases despite being largely preventable. However, professional advice on optimal oral hygiene practices is often forgotten or abandoned by patients. Therefore patients may benefit from…

Artificial Intelligence · Computer Science 2022-09-15 Anna L. Trella , Kelly W. Zhang , Inbal Nahum-Shani , Vivek Shetty , Finale Doshi-Velez , Susan A. Murphy

Introduction: For COVID-19 patients accurate prediction of disease severity and mortality risk would greatly improve care delivery and resource allocation. There are many patient-related factors, such as pre-existing comorbidities that…

Medical treatments often involve a sequence of decisions, each informed by previous outcomes. This process closely aligns with reinforcement learning (RL), a framework for optimizing sequential decisions to maximize cumulative rewards under…

Machine Learning · Computer Science 2024-10-15 Ali Shirali , Alexander Schubert , Ahmed Alaa

For severely affected COVID-19 patients, it is crucial to identify high-risk patients and predict survival and need for intensive care (ICU). Most of the proposed models are not well reported making them less reproducible and prone to high…

Machine Learning · Computer Science 2024-03-29 Mahbubunnabi Tamala , Mohammad Marufur Rahmanb , Maryam Alhasimc , Mobarak Al Mulhimd , Mohamed Derichee

COVID-19 patient triaging with predictive outcome of the patients upon first present to emergency department (ED) is crucial for improving patient prognosis, as well as better hospital resources management and cross-infection control. We…

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