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Quantum computers have demonstrated utility in simulating quantum systems beyond brute-force classical approaches. As the community builds on these demonstrations to explore using quantum computing for applied research, algorithms and…

Analog quantum simulation leverages native hardware dynamics to emulate complex quantum systems with great efficiency by bypassing the quantum circuit abstraction. However, conventional compilation methods for analog simulators are…

Quantum Physics · Physics 2025-07-01 Junyu Zhou , Yuhao Liu , Shize Che , Anupam Mitra , Efekan Kökcü , Ermal Rrapaj , Costin Iancu , Gushu Li

Languages, compilers, and computer-aided design tools will be essential for scalable quantum computing, which promises an exponential leap in our ability to execute complex tasks. LIQUi|> is a modular software architecture designed to…

Quantum Physics · Physics 2014-02-20 Dave Wecker , Krysta M. Svore

It is becoming increasingly clear that, if a useful device for quantum computation will ever be built, it will be embodied by a classical computing machine with control over a truly quantum subsystem, this apparatus performing a mixture of…

Programming Languages · Computer Science 2009-11-07 S. Bettelli , L. Serafini , T. Calarco

Hybrid quantum computing systems that combine discrete-variable qubits with continuous-variable qumodes offer promising advantages for quantum simulation, error correction, and sensing applications. However, existing quantum software…

Quantum Physics · Physics 2026-03-12 Jim Furches , Timothy J. Stavenger , Carlos Ortiz Marrero

Recent computations involving quantum processing units (QPUs) have demonstrated a series of challenges inherent to hybrid classical-quantum programming, compilation, execution, and verification and validation. Despite considerable progress,…

Quantum Physics · Physics 2018-05-24 Alexander McCaskey , Eugene Dumitrescu , Dmitry Liakh , Travis Humble

The exploration of hybrid quantum-classical algorithms and programming models on noisy near-term quantum hardware has begun. As hybrid programs scale towards classical intractability, validation and benchmarking are critical to…

Quantum Physics · Physics 2019-03-06 Alexander McCaskey , Eugene Dumitrescu , Mengsu Chen , Dmitry Lyakh , Travis S. Humble

We describe Qiskit, a software development kit for quantum information science. We discuss the key design decisions that have shaped its development, and examine the software architecture and its core components. We demonstrate an…

To address the urgent need in the NISQ era for high-performance, scalable quantum compilers and to advance the integration of classical and quantum computing, we present QLLVM, an advanced Quantum-Classical co-compilation framework built on…

Quantum Physics · Physics 2026-04-17 Yu Zhu , Qiming Du , Yuqiong Jin , Woji He , Hang Lian , Xin Zhou , Jinchen Xu , Zheng Shan

High-Performance Computing (HPC) systems are the most powerful tools that we currently have to solve complex scientific simulations. Quantum computing (QC) has the potential to enhance HPC systems by accelerating the execution of specific…

Most quantum computers today are constrained by hardware limitations, particularly the number of available qubits, causing significant challenges for executing large-scale quantum algorithms. Circuit cutting has emerged as a key technique…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-06 Mar Tejedor , Berta Casas , Javier Conejero , Alba Cervera-Lierta , Rosa M. Badia

A widely-used quantum programming paradigm comprises of both the data flow and control flow. Existing quantum hardware cannot well support the control flow, significantly limiting the range of quantum software executable on the hardware. By…

To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-24 Xin Zhan , K. Grace Johnson , Aniello Esposito , Barbara Chapman , Marco Fiorentino , Kirk M. Bresniker , Raymond G. Beausoleil , Masoud Mohseni

Quantum simulations are designed to model quantum systems, and many compilation frameworks have been developed for executing such simulations on quantum computers. Most compilers leverage the capabilities of digital and analog quantum…

Quantum Physics · Physics 2025-09-26 Liyi Li , Federico Zahariev , Chandeepa Dissanayake , Jae Swanepoel , Amr Sabry , Mark S. Gordon

With the potential of quantum algorithms to solve intractable classical problems, quantum computing is rapidly evolving and more algorithms are being developed and optimized. Expressing these quantum algorithms using a high-level language…

Quantum Physics · Physics 2020-05-28 N. Khammassi , I. Ashraf , J. v. Someren , R. Nane , A. M. Krol , M. A. Rol , L. Lao , K. Bertels , C. G. Almudever

We present Qibolab, an open-source software library for quantum hardware control integrated with the Qibo quantum computing middleware framework. Qibolab provides the software layer required to automatically execute circuit-based algorithms…

Modeling composite systems of spins or electrons coupled to bosonic modes is of significant interest for many fields of applied quantum physics and chemistry. A quantum simulation can allow for the solution of quantum problems beyond…

A major hurdle to the deployment of quantum linear systems algorithms and recent quantum simulation algorithms lies in the difficulty to find inexpensive reversible circuits for arithmetic using existing hand coded methods. Motivated by…

Quantum Physics · Physics 2016-12-05 Mathias Soeken , Martin Roetteler , Nathan Wiebe , Giovanni De Micheli

We present a scalable, robust approach to creating quantum programs of arbitrary size and complexity. The approach is based on the true abstraction of the problem. The quantum program is expressed in terms of a high-level model together…

Fault-tolerant quantum computation promises to solve outstanding problems in quantum chemistry within the next decade. Realizing this promise requires scalable tools that allow users to translate descriptions of electronic structure…