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The outbreak of COVID-19 in 2020 has led to a surge in the interest in the mathematical modeling of infectious diseases. Disease transmission may be modeled as compartmental models, in which the population under study is divided into…

Populations and Evolution · Quantitative Biology 2020-10-27 Malú Grave , Alvaro L. G. A. Coutinho

Novel Coronavirus (COVID-19) has drastically overwhelmed more than 200 countries affecting millions and claiming almost 1 million lives, since its emergence in late 2019. This highly contagious disease can easily spread, and if not…

COVID-19 testing, the cornerstone for effective screening and identification of COVID-19 cases, remains paramount as an intervention tool to curb the spread of COVID-19 both at local and national levels. However, the speed at which the…

Repeated asymptomatic screening for SARS-CoV-2 promises to control spread of the virus but would require too many resources to implement at scale. Group testing is promising for screening more people with fewer test resources: multiple…

Populations and Evolution · Quantitative Biology 2020-11-18 Yifan Lin , Yuxuan Ren , Jingyuan Wan , Massey Cashore , Jiayue Wan , Yujia Zhang , Peter Frazier , Enlu Zhou

We present a method for efficient estimation of the prevalence of infection in a population with high accuracy using only a small number of tests. The presented approach uses pool testing with a mix of pool sizes of various sizes. The test…

Applications · Statistics 2020-04-08 Itsik Bergel

Emerging in December 2019, the COVID-19 pandemic caused widespread health, economic, and social disruptions. Rapid global transmission overwhelmed healthcare systems, resulting in high infection rates, hospitalisations, and fatalities. To…

Populations and Evolution · Quantitative Biology 2025-10-08 Zacharias Komodromos , Kleanthis Malialis , Panayiotis Kolios

Rapid antigen tests detect proteins at the surface of virus particles, identifying the disease during its infectious phase. In contrast, PCR tests detect viral genomes; they can thus diagnose COVID-19 before the infectious phase but also…

Populations and Evolution · Quantitative Biology 2022-01-21 Jitka Polechová , Kory D. Johnson , Pavel Payne , Alex Crozier , Mathias Beiglböck , Pavel Plevka , Eva Schernhammer

Millions of people have died worldwide from COVID-19. In addition to its high death toll, COVID-19 has led to unbearable suffering for individuals and a huge global burden to the healthcare sector. Therefore, researchers have been trying to…

Sound · Computer Science 2023-11-14 Sudip Vhaduri , Seungyeon Paik , Jessica E Huber

This paper presents a critical analysis of the literature and perspective research ideas for modeling the epidemics caused by the SARS-CoV-2 virus. It goes beyond deterministic population dynamics to consider several key complexity features…

Populations and Evolution · Quantitative Biology 2025-01-24 Giulia Bertaglia , Andrea Bondesan , Diletta Burini , Raluca Eftimie , Lorenzo Pareschi , Giuseppe Toscani

COVID-19 remains a challenging global threat with ongoing waves of infections and clinical disease which have resulted millions of deaths and an enormous strain on health systems worldwide. Effective vaccines have been developed for the…

In a previous note we made an analysis of the spreading of the COVID disease in Italy. We used a model based on the logistic and Hubbert functions, the analysis we exploited has shown limited usefulness in terms of predictions and failed in…

Populations and Evolution · Quantitative Biology 2020-03-31 Giuseppe Dattoli , Emanuele Di Palma , Silvia Licciardi , Elio Sabia

We propose a novel infection spread model based on a random connection graph which represents connections between $n$ individuals. Infection spreads via connections between individuals and this results in a probabilistic cluster formation…

Information Theory · Computer Science 2022-03-30 Batuhan Arasli , Sennur Ulukus

System modeling is a classical approach to ensure their reliability since it is suitable both for a formal verification and for software testing techniques. In the context of model-based testing an approach combining random testing and…

Software Engineering · Computer Science 2018-06-14 Julien Bernard , Pierre-Cyrille Héam , Olga Kouchnarenko

Estimates from infectious disease models have constituted a significant part of the scientific evidence used to inform the response to the COVID-19 pandemic in the UK. These estimates can vary strikingly in their bias and variability.…

Applications · Statistics 2022-10-12 R. E. Moore , C. Rosato , S. Maskell

The purpose of this work is to give a contribution to the understanding of the COVID-19 contagion in Italy. To this end, we developed a modified Susceptible-Infected-Recovered (SIR) model for the contagion, and we used official data of the…

Physics and Society · Physics 2020-04-01 Giuseppe C. Calafiore , Carlo Novara , Corrado Possieri

Motivated by the rapid spread of COVID-19 all across the globe, we have performed simulations of a system dynamic epidemic spread model in different possible situations. The simulation, not only captures the model dynamic of the spread of…

Populations and Evolution · Quantitative Biology 2020-04-02 Kashif Zia , Umar Farooq

Recent epidemiological data report that worldwide more than 53 million people have been infected by SARS-CoV-2, resulting in 1.3 million deaths. The disease has been spreading very rapidly and few months after the identification of the…

When testing for a disease such as COVID-19, the standard method is individual testing: we take a sample from each individual and test these samples separately. An alternative is pooled testing (or "group testing"), where samples are mixed…

Applications · Statistics 2021-12-14 Matthew Aldridge , David Ellis

During 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission has been increasing amongst the world's population at an alarming rate. Reducing the spread of SARS-CoV-2 and other diseases that are spread in…

Social and Information Networks · Computer Science 2022-03-22 Patrick Urrutia , David Wren , Chrysafis Vogiatzis , Ruriko Yoshida

The recent spreading of coronavirus made many countries impose restrictions in order to control its dangerous effect on the citizens. We developed a theoretical dynamical model based on compartmental SIR system with additional adjustment…

Physics and Society · Physics 2020-05-08 Victoria Lopez , Milena Čukić