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The cellular environment is crowded with macromolecules of different shapes and sizes. The effect of this macromolecular crowding has been studied in a variety of synthetic crowding environments: two popular examples are the compact…

Soft Condensed Matter · Physics 2023-09-21 Stephen J. Spencer , Venketesh Thrithamara Ranganathan , Anand Yethiraj , G. Todd Andrews

We report on a joint experimental-theoretical study of collective diffusion in, and static shear viscosity of solutions of bovine serum albumin (BSA) proteins, focusing on the dependence on protein and salt concentration. Data obtained from…

The process of drying is a simple physical mechanism that drives a system to relax from one equilibrium point to another. The native states of the constituent particles in the droplets can be linked to the emergent morphological patterns…

Soft Condensed Matter · Physics 2021-05-14 Anusuya Pal , Amalesh Gope , Germano S. Iannacchione

Pattern formation in drying protein droplets continues to attract considerable research attention because it can be linked to specific protein-protein interactions. An extensive study of the drying evolution and the final crack patterns are…

Soft Condensed Matter · Physics 2020-04-14 Anusuya Pal , Amalesh Gope , Ari S. Athair , Germano S. Iannacchione

Using lubrication theory, drying processes of sessile colloidal droplets on a solid substrate are studied. A simple model is proposed to describe temporal dynamics both the shape of the drop and the volume fraction of the colloidal…

Soft Condensed Matter · Physics 2011-12-20 Yu. Yu. Tarasevich , I. V. Vodolazskaya , O. P. Isakova

Drying of biologically-relevant sessile droplets, including passive systems (like DNA and proteins), as well as active microbial systems comprising bacteria and algae, have garnered considerable attention over the last decades. Distinct…

Soft Condensed Matter · Physics 2023-11-07 Anusuya Pal , Amalesh Gope , Anupam Sengupta

Image processing and pattern recognition offer a useful and versatile method for optically characterizing drops of a colloidal solution during the drying process and in its final state. This paper exploits image processing techniques…

Soft Condensed Matter · Physics 2020-02-11 Anusuya Pal , Amalesh Gope , Germano S. Iannacchione

The present paper proposes a novel method of quantification of the variation in biofilm architecture, in correlation with the alteration of growth conditions that include, variations of substrate and conditioning layer. The polymeric…

Biological Physics · Physics 2018-01-30 Suparna Dutta Sinha , Saptarshi Das , Sujata Tarafdar , Tapati Dutta

Sessile drying droplets manifest distinct morphological patterns, encompassing diverse systems viz., DNA, proteins, blood, and protein-liquid crystal (LC) complexes. This study employs an integrated methodology that combines drying droplet,…

Soft Condensed Matter · Physics 2024-01-23 Anusuya Pal , Amalesh Gope

Using neutron reflectivity together with an appropriate electrochemical cell, we have studied the effects of transverse electric field on the Bovine Serum Albumin (BSA) monolayer initially adsorbed at the interface of the aqueous solution…

Soft Condensed Matter · Physics 2015-03-19 A. Koutsioubas , D. Lairez , G. Zalczer , F. Cousin

A static light scattering (SLS) study of bovine serum albumin (BSA) mixtures with two anionic graft copolymers of poly (sodium acrylate-co-sodium 2-acrylamido-2-methyl-1-propanesulphonate)-graft-poly (N, N-dimethylacrylamide), with a high…

Soft Condensed Matter · Physics 2007-05-28 Evaggelia Serefoglou , Julian Oberdisse , Georgios Staikos

The dynamics of two vertically coalescing drops and a pool of the same liquid have been investigated using a Coupled Level Set and Volume of Fluid (CLSVOF) method. Such a configuration enables us to study the dynamic interaction of an…

Fluid Dynamics · Physics 2023-08-08 Akash Paul , Bahni Ray , Kirti Chandra Sahu , Gautam Biswas

The control of biofilm formation is a challenging goal that has not been reached yet in many aspects. One is the role of van der Waals forces and another the importance of mutual interactions between the adsorbing and the adsorbed…

Soft Condensed Matter · Physics 2019-08-12 Y. Schmitt , H. Hähl , C. Gilow , H. Mantz , K. Jacobs , O. Leidinger , M. Bellion , L. Santen

Bovine serum albumin (BSA) Langmuir monolayer, as a model of biomineralization-associated proteins, was used to study its effect on regulated biomineralization of calcium carbonate. The effects of the BSA Langmuir monolayer and the…

Materials Science · Physics 2011-06-15 Zhong-Hui Xue , Shu-Xi Dai , Bin-Bin Hu , Zu-Liang Du

We performed a thorough investigation of the drying dynamics of a charged colloidal dispersion drop in a confined geometry. We developed an original methodology based on Raman micro-spectroscopy to measure spatially-resolved colloids…

Soft Condensed Matter · Physics 2016-12-13 Charles Loussert , Anne Bouchaudy , Jean-Baptiste Salmon

By means of a minimal physical model, we investigate the interplay of two phase transitions at play in chromatin organization: (1) liquid-liquid phase separation (LLPS) within the fluid solvating chromatin, resulting in the formation of…

Biological Physics · Physics 2024-09-24 Reda Tiani , Marie Jardat , Vincent Dahirel

Salts are an integral part of the environment for living systems and, therefore, understanding their effects on proteins and other biomolecules is of fundamental interest. Small-angle X-ray scattering (SAXS) of protein solutions can provide…

Biomolecules · Quantitative Biology 2026-05-01 Anshika Dhiman , Sanbo Qin , Huan-Xiang Zhou

The "chemical bond" is a central concept in molecular sciences, but there is no consensus as to what a bond actually is. Therefore, a variety of bonding models have been developed, each defining the structure of molecules in a different…

Chemical Physics · Physics 2016-05-03 Amanda Morgenstern

A new theoretical method, referred to as Generalized Langevin Mode Analysis (GLMA), is proposed to analyze the mode of structural fluctuations of a biomolecule in solution. The method combines the two theories in the statistical mechanics,…

Statistical Mechanics · Physics 2022-05-20 Masatake Sugita , Fumio Hirata

We analyze the information content of density profiles for an ultracold Bose gas of atoms and extract resolution limits for observables contained in these images. Our starting point is density correlations that we compute within the…

Quantum Physics · Physics 2008-08-27 Antonio Negretti , Carsten Henkel , Klaus Molmer
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