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After admission to emergency department (ED), patients with critical illnesses are transferred to intensive care unit (ICU) due to unexpected clinical deterioration occurrence. Identifying such unplanned ICU transfers is urgently needed for…

Machine Learning · Computer Science 2021-02-10 Chun-An Chou , Qingtao Cao , Shao-Jen Weng , Che-Hung Tsai

Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

Spectral clustering is a celebrated algorithm that partitions objects based on pairwise similarity information. While this approach has been successfully applied to a variety of domains, it comes with limitations. The reason is that there…

Statistics Theory · Mathematics 2018-05-24 Kwangjun Ahn , Kangwook Lee , Changho Suh

Magnetic resonance imaging (MRI) is a central modality for stroke imaging. It is used upon patient admission to make treatment decisions such as selecting patients for intravenous thrombolysis or endovascular therapy. MRI is later used in…

The accurate assessment of White matter hyperintensities (WMH) burden is of crucial importance for epidemiological studies to determine association between WMHs, cognitive and clinical data. The manual delineation of WMHs is tedious, costly…

Tissues and Organs · Quantitative Biology 2018-01-03 R. Guerrero , C. Qin , O. Oktay , C. Bowles , L. Chen , R. Joules , R. Wolz , M. C. Valdes-Hernandez , D. A. Dickie , J. Wardlaw , D. Rueckert

Hyperspectral unmixing is a blind source separation problem which consists in estimating the reference spectral signatures contained in a hyperspectral image, as well as their relative contribution to each pixel according to a given mixture…

Data Analysis, Statistics and Probability · Physics 2017-11-21 Pierre-Antoine Thouvenin , Nicolas Dobigeon , Jean-Yves Tourneret

The skull segmentation from CT scans can be seen as an already solved problem. However, in MR this task has a significantly greater complexity due to the presence of soft tissues rather than bones. Capturing the bone structures from MR…

Image and Video Processing · Electrical Eng. & Systems 2024-10-18 Kamil Kwarciak , Mateusz Daniol , Daria Hemmerling , Marek Wodzinski

Time is a fundamental factor during stroke treatments. A fast, automatic approach that segments the ischemic regions helps treatment decisions. In clinical use today, a set of color-coded parametric maps generated from computed tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Luca Tomasetti , Mahdieh Khanmohammadi , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz

The high rate of false alarms in intensive care units (ICUs) is one of the top challenges of using medical technology in hospitals. These false alarms are often caused by patients' movements, detachment of monitoring sensors, or different…

Machine Learning · Computer Science 2019-04-19 Behzad Ghazanfari , Fatemeh Afghah , Kayvan Najarian , Sajad Mousavi , Jonathan Gryak , James Todd

Surgical instrument segmentation (SIS) on endoscopic images stands as a long-standing and essential task in the context of computer-assisted interventions for boosting minimally invasive surgery. Given the recent surge of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Mingyu Sheng , Jianan Fan , Dongnan Liu , Ron Kikinis , Weidong Cai

The increasing complexity of medical imaging data underscores the need for advanced anomaly detection methods to automatically identify diverse pathologies. Current methods face challenges in capturing the broad spectrum of anomalies, often…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Cosmin I. Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel

This work explores the use of computer vision for image segmentation and classification of medical fluid samples in transparent containers (for example, tubes, syringes, infusion bags). Handling fluids such as infusion fluids, blood, and…

Computer Vision and Pattern Recognition · Computer Science 2021-05-05 Sagi Eppel , Haoping Xu , Alan Aspuru-Guzik

Intracranial hemorrhage (ICH) secondary to Traumatic Brain Injury (TBI) represents a critical diagnostic challenge, with approximately 64,000 TBI-related deaths annually in the United States. Current diagnostic modalities including Computed…

Image and Video Processing · Electrical Eng. & Systems 2025-10-27 Phat Tran , Enbai Kuang , Fred Xu

Accurate segmentation of organs at risk in the head and neck is essential for radiation therapy, yet deep learning models often fail on small, complexly shaped organs. While hybrid architectures that combine different models show promise,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Xiaoyu Liu , Siwen Wei , Linhao Qu , Mingyuan Pan , Chengsheng Zhang , Yonghong Shi , Zhijian Song

Local discriminative representation is needed in many medical image analysis tasks such as identifying sub-types of lesion or segmenting detailed components of anatomical structures. However, the commonly applied supervised representation…

Computer Vision and Pattern Recognition · Computer Science 2021-03-25 Huai Chen , Jieyu Li , Renzhen Wang , Yijie Huang , Fanrui Meng , Deyu Meng , Qing Peng , Lisheng Wang

Unsupervised anomaly segmentation approaches to pathology segmentation train a model on images of healthy subjects, that they define as the 'normal' data distribution. At inference, they aim to segment any pathologies in new images as…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Ziyun Liang , Xiaoqing Guo , J. Alison Noble , Konstantinos Kamnitsas

Detecting brain lesions as abnormalities observed in magnetic resonance imaging (MRI) is essential for diagnosis and treatment. In the search of abnormalities, such as tumors and malformations, radiologists may benefit from computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Hassan Baker , Austin J. Brockmeier

With the rapid increase of compound databases available in medicinal and material science, there is a growing need for learning representations of molecules in a semi-supervised manner. In this paper, we propose an unsupervised hierarchical…

Machine Learning · Statistics 2017-11-30 Hai Nguyen , Shin-ichi Maeda , Kenta Oono

Automatic intracranial hemorrhage segmentation in 3D non-contrast head CT (NCCT) scans is significant in clinical practice. Existing hemorrhage segmentation methods usually ignores the anisotropic nature of the NCCT, and are evaluated on…

Many key problems in machine learning and data science are routinely modeled as optimization problems and solved via optimization algorithms. With the increase of the volume of data and the size and complexity of the statistical models used…

Optimization and Control · Mathematics 2020-08-28 Filip Hanzely