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Scientific applications that involve simulation ensembles can be accelerated greatly by using experiment design methods to select the best simulations to perform. Methods that use machine learning (ML) to create proxy models of simulations…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-16 Logan Ward , Ganesh Sivaraman , J. Gregory Pauloski , Yadu Babuji , Ryan Chard , Naveen Dandu , Paul C. Redfern , Rajeev S. Assary , Kyle Chard , Larry A. Curtiss , Rajeev Thakur , Ian Foster

We present PolyHoop, a lightweight standalone C++ implementation of a mechanical model to simulate the dynamics of soft particles and cellular tissues in two dimensions. With only few geometrical and physical parameters, PolyHoop is capable…

Soft Condensed Matter · Physics 2024-02-22 Roman Vetter , Steve V. M. Runser , Dagmar Iber

The presence of nanoparticles in a diblock copolymer leads to changes in the morphology and properties of the matrix and can produce highly organized hybrid materials. The resulting material properties depend not only on the polymer…

Soft Condensed Matter · Physics 2018-05-30 Javier Diaz , Marco Pinna , Andrei Zvelindovsky , Adelchi Asta , Ignacio Pagonabarraga

Numerical simulations are ubiquitous in mathematics and computational science. Several industrial and clinical applications entail modeling complex multiphysics systems that evolve over a variety of spatial and temporal scales. This study…

Mathematical Software · Computer Science 2022-11-14 Pasquale Claudio Africa

We propose an efficient Monte Carlo algorithm for the off-lattice simulation of dense hard sphere polymer melts using cluster moves, called event chains, which allow for a rejection-free treatment of the excluded volume. Event chains also…

Soft Condensed Matter · Physics 2015-09-24 Tobias Alexander Kampmann , Horst-Holger Boltz , Jan Kierfeld

We introduce PULSEDYN, a particle dynamics program in $C++$, to solve many-body nonlinear systems in one dimension. PULSEDYN is designed to make computing accessible to non-specialists in the field of nonlinear dynamics of many-body systems…

Computational Physics · Physics 2017-10-27 Rahul Kashyap , Surajit Sen

The rational design of novel polymers with tailored material properties has been a long-standing challenge in the field due to the large number of possible polymer design variables. To accelerate this design process, there is a critical…

Soft Condensed Matter · Physics 2025-04-11 Vinson Liao , Arthi Jayaraman

All simulation approaches eventually face limits in computational scalability when applied to large spatiotemporal domains. This challenge becomes especially apparent in molecular-level particle simulations, where high spatial and temporal…

Computational Physics · Physics 2025-10-23 Matthias Busch , Gregor Häfner , Jiayu Xie , Marius Tacke , Marcus Müller , Christian J. Cyron , Roland C. Aydin

Generation and analysis of time-series data is relevant to many quantitative fields ranging from economics to fluid mechanics. In the physical sciences, structures such as metastable and coherent sets, slow relaxation processes, collective…

Systems composed of soft matter (e.g., liquids, polymers, foams, gels, colloids, and most biological materials) are ubiquitous in science and engineering, but molecular simulations of such systems pose particular computational challenges,…

Bayesian Networks (BNs) are used in various fields for modeling, prediction, and decision making. pgmpy is a python package that provides a collection of algorithms and tools to work with BNs and related models. It implements algorithms for…

Machine Learning · Computer Science 2023-04-19 Ankur Ankan , Johannes Textor

Realistic simulations of detailed, biophysics-based, multi-scale models require very high resolution and, thus, large-scale compute facilities. Existing simulation environments, especially for biomedical applications, are designed to allow…

Computational Engineering, Finance, and Science · Computer Science 2018-02-12 Chris Bradley , Nehzat Emamy , Thomas Ertl , Dominik Göddeke , Andreas Hessenthaler , Thomas Klotz , Aaron Krämer , Michael Krone , Benjamin Maier , Miriam Mehl , Tobias Rau , Oliver Röhrle

We describe collective-move Monte Carlo algorithms designed to approximate the overdamped dynamics of self-assembling nanoscale components equipped with strong, short-ranged and anisotropic interactions. Conventional Monte Carlo simulations…

Statistical Mechanics · Physics 2012-04-16 Stephen Whitelam

The field of machine learning for drug discovery is witnessing an explosion of novel methods. These methods are often benchmarked on simple physicochemical properties such as solubility or general druglikeness, which can be readily…

Open material databases storing hundreds of thousands of material structures and their corresponding properties have become the cornerstone of modern computational materials science. Yet, the raw outputs of the simulations, such as the…

The breakdown of dynamical scaling for a dilute polymer solution in 2D has been suggested by Shannon and Choy [Phys. Rev. Lett. {\bf 79}, 1455 (1997)]. However, we show here both numerically and analytically that dynamical scaling holds…

Soft Condensed Matter · Physics 2009-11-10 E. Falck , O. Punkkinen , I. Vattulainen , T. Ala-Nissila

multisphere is an open-source Python package for generating multi-sphere representations of complex particles for use in DEM simulations. It reconstructs triangulated surface meshes and voxelized volumes as sets of intersecting spheres and…

Soft Condensed Matter · Physics 2026-04-23 Felix Buchele , Patric Müller , Thorsten Pöschel

This paper introduces the practicalities and benefits of using SimPy, a discrete event simulation (DES) module written in Python, for modeling and simulating complex systems. Through a step-by-step exploration of the classical Dining…

Mathematical Software · Computer Science 2024-05-06 Dmitry Zinoviev

This paper introduces and evaluates a freely available cellular nonlinear network simulator optimized for the effective use of GPUs, to achieve fast modelling and simulations. Its relevance is demonstrated for several applications in…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-02-23 Radu Dogaru , Ioana Dogaru

Simulation of non-adiabatic dynamics of a quantum system coupled to dissipative environments poses significant challenges. New sophisticated methods are regularly being developed with an eye towards moving to larger systems and more…

Quantum Physics · Physics 2023-06-07 Amartya Bose
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