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Macroevolution is considered as a problem of stochastic dynamics in a system with many competing agents. Evolutionary events (speciations and extinctions) are triggered by fitness records found by random exploration of the agents' fitness…

adap-org · Physics 2017-01-11 Paolo Sibani , Michael Brandt , Preben Alstroem

We consider a stochastic individual-based model of adaptive dynamics on a finite trait graph $G=(V,E)$. The evolution is driven by a linear birth rate, a density dependent logistic death rate an the possibility of mutations along the…

Probability · Mathematics 2024-04-08 Manuel Esser , Anna Kraut

This piece serves two purposes. Firstly, it aims at elucidating the role of epistasis in shaping, at a molecular level, the evolutionary paths of proteins, as well as the extent to which these epistatic effects are the outcome of an…

Populations and Evolution · Quantitative Biology 2025-08-01 Jorge A. Vila

Geographic ranges of communities of species evolve in response to environmental, ecological, and evolutionary forces. Understanding the effects of these forces on species' range dynamics is a major goal of spatial ecology. Previous…

Populations and Evolution · Quantitative Biology 2022-02-02 Farshad Shirani , Judith R. Miller

Under the effect of strong genetic drift, it is highly probable to observe gene fixation or gene loss in a population, shown by infinite peaks on a coherently constructed potential energy landscape. It is then important to ask what such…

Populations and Evolution · Quantitative Biology 2015-06-15 Song Xu , Shuyun Jiao , Pengyao Jiang , Ping Ao

To our knowledge, the populations are generally assumed to be homogeneous in the traditional approach to evolutionary game dynamics. Here, we focus on the inhomogeneous populations. A simple model which can describe the inhomogeneity of the…

Physics and Society · Physics 2007-05-23 Xiaojie Chen , Feng Fu , Long Wang , Tianguang Chu

Markov models of character substitution on phylogenies form the foundation of phylogenetic inference frameworks. Early models made the simplifying assumption that the substitution process is homogeneous over time and across sites in the…

Populations and Evolution · Quantitative Biology 2019-06-13 Guy Baele , Mandev S. Gill , Philippe Lemey , Marc A. Suchard

Cells can often choose among several stably heritable phenotypes. Examples are the expression of genes in eukaryotic cells where long chromosomal regions can adopt persistent and heritable silenced or active states, that may be associated…

Molecular Networks · Quantitative Biology 2015-05-18 Mille A. Micheelsen , Namiko Mitarai , Kim Sneppen , Ian. B. Dodd

Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random…

Biological Physics · Physics 2009-11-07 L. C. Hsieh , L. F. Luo , F. M. Ji , H. C. Lee

The genotype-fitness map plays a fundamental role in shaping the dynamics of evolution. However, it is difficult to directly measure a fitness landscape in practice, because the number of possible genotypes is astronomical. One approach is…

Populations and Evolution · Quantitative Biology 2014-11-11 Jakub Otwinowski , Joshua B. Plotkin

We analyst in detail a new approach to the monitoring and forecasting of the onset of transitions in high dimensional complex systems (see Phys. Rev. Lett . vol. 113, 264102 (2014)) by application to the Tangled Nature Model of evolutionary…

Adaptation and Self-Organizing Systems · Physics 2015-08-03 Duccio Piovani , Jelena Grujic , Henrik Jeldtoft Jensen

Species sharing a habitat will co-evolve to make use of the available resources, as consumption is modulated by competition and negative feedback loops between consumers and resources. The dietary range of a given species determines the…

Populations and Evolution · Quantitative Biology 2026-05-28 Elliot M. Butterworth , Tim Rogers

We present some results of simulations of population growth and evolution, using the standard asexual Penna model, with individuals characterized by a string of bits representing a genome containing some possible mutations. After about…

Populations and Evolution · Quantitative Biology 2009-11-11 Mikolaj Sitarz , Andrzej Z. Maksymowicz

Epigenetics plays a key role in cellular differentiation and maintaining cell identity, enabling cells to regulate their genetic activity without altering the DNA sequence. Epigenetic regulation occurs within the context of hierarchically…

Quantitative Methods · Quantitative Biology 2024-09-11 Daria Stepanova , Meritxell Brunet Guasch , Helen M. Byrne , Tomás Alarcón

Recent research on the non-stationary nature of the dynamics of complex systems is reviewed through three specific models. The long time dynamics consists of a slow, decelerating but spasmodic release of generalized intrinsic strain. These…

Statistical Mechanics · Physics 2007-05-23 Henrik Jeldtoft Jensen

We propose a new procedure to monitor and forecast the onset of transitions in high dimensional complex systems. We describe our procedure by an application to the Tangled Nature model of evolutionary ecology. The quasi-stable…

Adaptation and Self-Organizing Systems · Physics 2014-12-31 Andrea Cairoli , Duccio Piovani , Henrik Jeldtoft Jensen

We consider a fixed size population that undergoes an evolutionary adaptation in the weak mutuation rate limit, which we model as a biased Langevin process in the genotype space. We show analytically and numerically that, if the fitness…

Populations and Evolution · Quantitative Biology 2014-02-04 Jakub Otwinowski , Sorin Tanase-Nicola , Ilya Nemenman

The contribution to an organism's phenotype from one genetic locus may depend upon the status of other loci. Such epistatic interactions among loci are now recognized as fundamental to shaping the process of adaptation in evolving…

Populations and Evolution · Quantitative Biology 2012-12-18 Jeremy A. Draghi , Joshua B. Plotkin

We use a Convolutional Recurrent Neural Network approach to learn morphological evolution driven by surface diffusion. To this aim we first produce a training set using phase field simulations. Intentionally, we insert in such a set only…

Computational Physics · Physics 2024-05-07 Daniele Lanzoni , Marco Albani , Roberto Bergamaschini , Francesco Montalenti

Most theories of evolutionary diversification are based on equilibrium assumptions: they are either based on optimality arguments involving static fitness landscapes, or they assume that populations first evolve to an equilibrium state…

Populations and Evolution · Quantitative Biology 2017-02-07 Iaroslav Ispolatov , Vaibhav Madhok , Michael Doebeli