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Optical diffraction tomography (ODT) is a tomographic technique that can be used to measure the three-dimensional (3D) refractive index distribution within living cells without the requirement of any marker. In principle, ODT can be…

Quantitative Methods · Quantitative Biology 2018-01-03 Paul Müller , Mirjam Schürmann , Chii J. Chan , Jochen Guck

We demonstrate experimentally ghost optical coherence tomography using a broadband incoherent supercontinuum light source with shot-to-shot random spectral fluctuations. The technique is based on ghost imaging in the spectral domain where…

Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

Optical coherence tomography (OCT) is a noninvasive technology that enables real-time imaging of tissue microanatomies. The axial resolution of OCT is intrinsically constrained by the spectral bandwidth of the employed light source while…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Kaiyan Li , Jingyuan Yang , Wenxuan Liang , Xingde Li , Chenxi Zhang , Lulu Chen , Chan Wu , Xiao Zhang , Zhiyan Xu , Yuelin Wang , Lihui Meng , Yue Zhang , Youxin Chen , S. Kevin Zhou

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

Coherent extreme ultraviolet (XUV) radiation produced by table-top high-harmonic generation (HHG) sources provides a wealth of possibilities in research areas ranging from attosecond physics to high resolution coherent imaging. However, it…

Optics · Physics 2016-10-28 G. S. M. Jansen , D. Rudolf , L. Freisem , K. S. E. Eikema , S. Witte

Ultrafast science and technology have brought in burgeoning opportunities to optical metrology, strong-field physics, non-equilibrium physics, etc., through light-matter interaction due to ever-advancing temporal resolution and peak power…

Optics · Physics 2022-11-28 Yi Chan , Fu Deng , Jingdi Zhang

Transmission optical coherence tomography (OCT) enables analysis of biological specimens in vitro through detection of forward scattered light. Up to now, transmission OCT was considered as a technique that cannot directly retrieve…

Optics · Physics 2024-05-24 Wojciech Krauze , Martyna Mazur , Arkadiusz Kuś

Despite the extensive demonstration of robotic systems for both cataract and vitreoretinal procedures, existing technologies or mechanisms still possess insufficient accuracy, precision, and degrees of freedom for instrument manipulation or…

Robotics · Computer Science 2025-11-04 Yu-Ting Lai , Jacob Rosen , Yasamin Foroutani , Ji Ma , Wen-Cheng Wu , Jean-Pierre Hubschman , Tsu-Chin Tsao

We demonstrate incoherent broadband cavity enhanced absorption spectroscopy in the mid-infrared wave- length range from 3000 to 3450 nm using an all-fiber based supercontinuum source. Multi-components gas detection is performed and…

Instrumentation and Detectors · Physics 2017-09-13 Caroline Amiot , Antti Aalto , Piotr Ryczkowski , Juha Toivonen , Goëry Genty

We demonstrate the first cavity-enhanced optical frequency comb spectroscopy in the mid-infrared wavelength region and report the sensitive real-time trace detection of hydrogen peroxide in the presence of a large amount of water. The…

We consider the use of optical coherence tomography (OCT) imaging to predict the quality of meat. We find that intramuscular fat (IMF) absorbs infrared light about nine times stronger than muscle, which enables us to estimate fat content in…

Applied Physics · Physics 2020-05-27 Abi Thampi , Sam Hitchman , Stéphane Coen , Frédérique Vanholsbeeck

Optical coherence tomography angiography (OCTA) is a new imaging modality to visualize retinal microvasculature and has been readily adopted in clinics. High-resolution OCT angiograms are important to qualitatively and quantitatively…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Yuyan Ruan , Dawei Yang , Ziqi Tang , An Ran Ran , Carol Y. Cheung , Hao Chen

Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital…

Existing super-resolution methods of optical imaging hold a solid place as an application in natural sciences, but many new developments allow for beating the diffraction limit in a more subtle way. One of the recently explored strategies…

Quantum Physics · Physics 2022-02-08 Mateusz Mazelanik , Adam Leszczyński , Michał Parniak

In ultra-high resolution (UHR-) optical coherence tomography (OCT) group velocity dispersion (GVD) must be corrected for in order to approach the theoretical resolution limit. One approach promises not only compensation, but complete…

An inertial sensor design is proposed in this paper to achieve high sensitivity and large dynamic range in the sub-Hz frequency regime. High acceleration sensitivity is obtained by combining optical cavity readout systems with…

Quantum Physics · Physics 2022-09-23 Yanqi Zhang , Adam Hines , Dalziel Wilson , Felipe Guzman

Recent advances in the field of attosecond science hold the promise of tracking electronic processes at the shortest space and time scales. Imaging methods that combine attosecond temporal with nanometer spatial resolution are currently out…

Optical Coherence Tomography (OCT) imaging is pivotal in diagnosing ophthalmic conditions by providing detailed cross-sectional images of the anterior and posterior segments of the eye. Nonetheless, speckle noise and other imaging artifacts…

Image and Video Processing · Electrical Eng. & Systems 2024-09-26 Akkidas Noel Prakash , Jahnvi Sai Ganta , Ramaswami Krishnadas , Tin A. Tunc , Satish K Panda

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

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