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Background: Quantitative stress perfusion cardiovascular magnetic resonance (CMR) is a powerful tool for assessing myocardial ischemia. Motion correction is essential for accurate pixel-wise mapping but traditional registration-based…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Noortje I. P. Schueler , Nathan C. K. Wong , Richard J. Crawley , Josien P. W. Pluim , Amedeo Chiribiri , Cian M. Scannell

Myocardial perfusion cardiovascular magnetic resonance (pCMR) using first-pass contrast-enhanced imaging could play an important role in the detection of epicardial and microvascular coronary artery disease. Recently, the emergence of…

Cardiovascular magnetic resonance (CMR) imaging is a standard imaging modality for assessing cardiovascular diseases (CVDs), the leading cause of death globally. CMR enables accurate quantification of the cardiac chamber volume, ejection…

Motion free reconstruction of compressively sampled cardiac perfusion MR images is a challenging problem. It is due to the aliasing artifacts and the rapid contrast changes in the reconstructed perfusion images. In addition to the…

Image and Video Processing · Electrical Eng. & Systems 2019-04-11 Abdul Haseeb Ahmed , Ijaz M. Qureshi

Coronary Artery Disease (CAD) remains a leading cause of morbidity and mortality worldwide. Early detection is critical to recover patient outcomes and decrease healthcare costs. In recent years, machine learning (ML) advancements have…

Artificial Intelligence · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Coronary artery disease (CAD) is the most common cause of death globally, and its diagnosis is usually based on manual myocardial segmentation of Magnetic Resonance Imaging (MRI) sequences. As the manual segmentation is tedious,…

Image and Video Processing · Electrical Eng. & Systems 2023-02-27 Yutian Chen , Xiaowei Xu , Dewen Zeng , Yiyu Shi , Haiyun Yuan , Jian Zhuang , Yuhao Dong , Qianjun Jia , Meiping Huang

Recent development of quantitative myocardial blood flow (MBF) mapping allows direct evaluation of absolute myocardial perfusion, by computing pixel-wise flow maps. Clinical studies suggest quantitative evaluation would be more desirable…

Quantitative Methods · Quantitative Biology 2020-06-01 Hui Xue , Rhodri Davies , Louis AE Brown , Kristopher D Knott , Tushar Kotecha , Marianna Fontana , Sven Plein , James C Moon , Peter Kellman

Coronary Artery Disease (CAD) diagnostic to be a major global cause of death, necessitating innovative solutions. Addressing the critical importance of early CAD detection and its impact on the mortality rate, we propose the potential of…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Atitaya Phoemsuk , Vahid Abolghasemi

In recent years, cardiovascular diseases (CVDs) have become one of the leading causes of mortality globally. CVDs appear with minor symptoms and progressively get worse. The majority of people experience symptoms such as exhaustion,…

Quantitative myocardial perfusion mapping has advantages over qualitative assessment, including the ability to detect global flow reduction. However, it is not clinically available and remains as a research tool. Building upon the…

Image and Video Processing · Electrical Eng. & Systems 2019-10-17 Hui Xue , Louise A. E. Brown , Sonia Nielles-Vallespin , Sven Plein , Peter Kellman

Coronary heart disease (CHD) remains a top reason of mortality worldwide. This study introduces a novel approach by integrating patient-specific Multi-slice CT scans into CAD models and employing a one-dimensional numerical framework to…

Medical Physics · Physics 2025-07-01 Oeshee Roy , Priyanshu Ghosh , Sayan Karmakar , Supratim Saha

Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value,…

Computational Engineering, Finance, and Science · Computer Science 2025-08-04 Haizhou Yang , Jiyang Zhang , Ismael Z. Assi , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa

Coronary microvascular dysfunction (CMD), characterized by impaired regulation of blood flow in the coronary microcirculation, plays a key role in the pathogenesis of ischemic heart disease and is increasingly recognized as a contributor to…

Computational Engineering, Finance, and Science · Computer Science 2025-12-25 Haizhou Yang , Jiyang Zhang , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa

While machine learning approaches perform well on their training domain, they generally tend to fail in a real-world application. In cardiovascular magnetic resonance imaging (CMR), respiratory motion represents a major challenge in terms…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 Amin Ranem , John Kalkhof , Caner Özer , Anirban Mukhopadhyay , Ilkay Oksuz

Cardiovascular magnetic resonance (CMR) imaging is the gold standard for diagnosing several heart diseases due to its non-invasive nature and proper contrast. MR imaging is time-consuming because of signal acquisition and image formation…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Kian Anvari Hamedani , Narges Razizadeh , Shahabedin Nabavi , Mohsen Ebrahimi Moghaddam

The effectiveness of a cardiovascular magnetic resonance (CMR) scan depends on the ability of the operator to correctly tune the acquisition parameters to the subject being scanned and on the potential occurrence of imaging artefacts such…

Myocarditis is a significant cardiovascular disease (CVD) that poses a threat to the health of many individuals by causing damage to the myocardium. The occurrence of microbes and viruses, including the likes of HIV, plays a crucial role in…

Cardiac magnetic resonance imaging (CMR) has emerged as a valuable diagnostic tool for cardiac diseases. However, a limitation of CMR is its slow imaging speed, which causes patient discomfort and introduces artifacts in the images. There…

Flow analysis carried out using phase contrast cardiac magnetic resonance imaging (PC-CMR) enables the quantification of important parameters that are used in the assessment of cardiovascular function. An essential part of this analysis is…

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