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The brain is a system operating on multiple time scales, and characterisation of dynamics across time scales remains a challenge. One framework to study such dynamics is that of fractal geometry. However, currently there exists no…

Neurons and Cognition · Quantitative Biology 2018-12-12 Lucas G. S. França , José G. V. Miranda , Marco Leite , Niraj K. Sharma , Matthew C. Walker , Louis Lemieux , Yujiang Wang

Exploring the human brain networks during rest is a topic of great interest. Several structural and functional studies have previously been conducted to study the intrinsic brain networks. In this paper, we focus on investigating the human…

Neurons and Cognition · Quantitative Biology 2016-07-05 Aya Kabbara , Wassim El Falou , Mohamad Khalil , Fabrice Wendling , Mahmoud Hassan

Epileptic biomarkers play a crucial role in identifying the origin of seizures, an essential aspect of pre-surgical planning for epilepsy treatment. These biomarkers can vary significantly over time. By studying these temporal fluctuations,…

Signal Processing · Electrical Eng. & Systems 2025-11-11 Mehdi Zekriyapanah Gashti , Mostafa Mohammadpour , Hassan Eshkiki , Vahid Ghanbarizadeh

Brain source imaging is an important method for noninvasively characterizing brain activity using Electroencephalogram (EEG) or Magnetoencephalography (MEG) recordings. Traditional EEG/MEG Source Imaging (ESI) methods usually assume that…

Applications · Statistics 2019-06-07 Feng Liu , Li Wang , Yifei Lou , Rencang Li , Patrick Purdon

Over the past few decades, electroencephalography (EEG) monitoring has become a pivotal tool for diagnosing neurological disorders, particularly for detecting seizures. Epilepsy, one of the most prevalent neurological diseases worldwide,…

Machine Learning · Computer Science 2025-08-08 Andrea Pollastro , Francesco Isgrò , Roberto Prevete

Complex spatial connectivity patterns, such as interictal suppression and ictal propagation, complicate accurate drug-resistant epilepsy (DRE) seizure detection using stereotactic electroencephalography (SEEG) and traditional machine…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Yiping Wang , Peiren Wang , Zhenye Li , Fang Liu , Jinguo Huang

Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…

Neurons and Cognition · Quantitative Biology 2025-02-13 Xinglin Zeng , Yiran Li , Lin Hua , Ruoxi Lu , Lucas Lemos Franco , Peter Kochunov , Shuo Chen , John A Detre , Ze Wang

Identifying preictal states -- periods during which seizures are more likely to occur -- remains a central challenge in clinical computational neuroscience. In this study, we introduce a novel framework that embeds functional brain…

Neurons and Cognition · Quantitative Biology 2025-05-21 Steven Rico-Aparicio , Martin Guillemaud , Alice Longhena , Vincent Navarro , Louis Cousyn , Mario Chavez

In this work, we present a neuromorphic system that combines for the first time a neural recording headstage with a signal-to-spike conversion circuit and a multi-core spiking neural network (SNN) architecture on the same die for recording,…

Signal Processing · Electrical Eng. & Systems 2021-06-09 Mohammadali Sharifshazileh , Karla Burelo , Johannes Sarnthein , Giacomo Indiveri

Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the…

Quantitative Methods · Quantitative Biology 2020-11-17 Md Navid Akbar , Marianna La Rocca , Rachael Garner , Dominique Duncan , Deniz Erdoğmuş

EEG recordings contain rich information about neural activity but are subject to artifacts, noise, and superficial differences due to sensors, amplifiers, and filtering. Independent component analysis and automatic labeling of independent…

Machine Learning · Computer Science 2025-12-05 Austin Meek , Carlos H. Mendoza-Cardenas , Austin J. Brockmeier

Accurate automated analysis of electroencephalography (EEG) would largely help clinicians effectively monitor and diagnose patients with various brain diseases. Compared to supervised learning with labelled disease EEG data which can train…

Machine Learning · Computer Science 2022-07-05 Yaojia Zheng , Zhouwu Liu , Rong Mo , Ziyi Chen , Wei-shi Zheng , Ruixuan Wang

Objective: To identify if whole-brain structural network alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic-clonic seizures (FBTCS) differ from alterations in patients without FBTCS. Methods: We…

Epilepsy is a disorder of the nervous system that can affect people of any age group. With roughly 50 million people worldwide diagnosed with the disorder, it is one of the most common neurological disorders. The EEG is an indispensable…

Populations and Evolution · Quantitative Biology 2022-02-21 Niamh McCallan , Scot Davidson , Kok Yew Ng , Pardis Biglarbeigi , Dewar Finlay , Boon Leong Lan , James McLaughlin

Epilepsy is one of the most occurring neurological disease globally emerged back in 4000 BC. It is affecting around 50 million people of all ages these days. The trait of this disease is recurrent seizures. In the past few decades, the…

Machine Learning · Computer Science 2021-11-08 Virender Ranga , Shivam Gupta , Jyoti Meena , Priyansh Agrawal

Epilepsy is one of the most occurring neurological diseases. The main characteristic of this disease is a frequent seizure, which is an electrical imbalance in the brain. It is generally accompanied by shaking of body parts and even leads…

Machine Learning · Computer Science 2023-03-22 Shivam Gupta , Virender Ranga , Priyansh Agrawal

Objective: Epilepsy is a chronic neurological disorder characterized by the occurrence of spontaneous seizures, which affects about one percent of the world's population. Most of the current seizure detection approaches strongly rely on…

Signal Processing · Electrical Eng. & Systems 2020-02-04 Xiang Zhang , Lina Yao , Manqing Dong , Zhe Liu , Yu Zhang , Yong Li

This paper presents a novel graph convolutional neural network (GCNN)-based approach for improving the diagnosis of neurological diseases using scalp-electroencephalograms (EEGs). Although EEG is one of the main tests used for…

Signal Processing · Electrical Eng. & Systems 2020-11-25 Neeraj Wagh , Yogatheesan Varatharajah

Characterizing the brain dynamics during different cortical states can reveal valuable information about its patterns across various cognitive processes. In particular, studying the differences between awake and sleep stages can shed light…

Seizures are one of the defining symptoms in patients with epilepsy, and due to their unannounced occurrence, they can pose a severe risk for the individual that suffers it. New research efforts are showing a promising future for the…

Machine Learning · Computer Science 2021-08-09 Carlos H. Mendoza-Cardenas , Austin J. Brockmeier