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Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

Electrocorticography (ECoG) provides direct measurements of synchronized postsynaptic potentials at the exposed cortical surface. Patterns of signal covariance across ECoG sensors have been associated with diverse cognitive functions and…

Neurons and Cognition · Quantitative Biology 2017-06-20 Richard F. Betzel , John D. Medaglia , Ari E. Kahn , Jonathan Soffer , Daniel R. Schonhaut , Danielle S. Bassett

The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

Neurons and Cognition · Quantitative Biology 2021-02-03 Matteo Fraschini , Simone Maurizio La Cava , Luca Didaci , Luigi Barberini

Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Kevin Monteiro , Sam Nallaperuma-Herzberg , Martina Mason , Steve Niederer

Electroencephalography (EEG) underpins neuroscience, clinical neurophysiology, and brain-computer interfaces (BCIs), yet pronounced inter- and intra-subject variability limits reliability, reproducibility, and translation. This systematic…

Neurons and Cognition · Quantitative Biology 2026-02-03 Xuan-The Tran , Thien-Nhan Vo , Son-Tung Vu , Thoa-Thi Tran , Manh-Dat Nguyen , Thomas Do , Chin-Teng Lin

Patients with epilepsy can manifest short, sub-clinical epileptic "bursts" in addition to full-blown clinical seizures. We believe the relationship between these two classes of events---something not previously studied…

Machine Learning · Statistics 2014-07-29 Drausin F. Wulsin , Emily B. Fox , Brian Litt

Machine learning is playing an increasingly important role in medical image analysis, spawning new advances in the clinical application of neuroimaging. There have been some reviews on machine learning and epilepsy before, and they mainly…

Machine Learning · Computer Science 2021-11-03 Jie Yuan , Xuming Ran , Keyin Liu , Chen Yao , Yi Yao , Haiyan Wu , Quanying Liu

Epilepsy is known to drastically alter brain dynamics during seizures (ictal periods), but its effects on background (non-ictal) brain dynamics remain poorly understood. To investigate this, we analyzed an in-house dataset of brain activity…

We investigate assortativity of functional brain networks before, during, and after one-hundred epileptic seizures with different anatomical onset locations. We construct binary functional networks from multi-channel electroencephalographic…

Data Analysis, Statistics and Probability · Physics 2013-09-24 Stephan Bialonski , Klaus Lehnertz

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

We calculate a measure of statistical complexity from the global dynamics of electroencephalographic (EEG) signals from healthy subjects and epileptic patients, and are able to stablish a criterion to characterize the collective behavior in…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 M. Escalona-Moran , M. G. Cosenza , R. Lopez-Ruiz , P. Garcia

Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferred from diffusion-weighted MRI (DWI). However, publicly…

The presence of interictal epileptiform discharges (IEDs) in electroencephalogram (EEG) recordings is a critical biomarker of epilepsy. Even trained neurologists find detecting IEDs difficult, leading many practitioners to turn to machine…

Predicting seizure freedom is essential for tailoring epilepsy treatment. But accurate prediction remains challenging with traditional methods, especially with diverse patient populations. This study developed a deep learning-based graph…

Understanding the seizure initiation process and its propagation pattern(s) is a critical task in epilepsy research. Characteristics of the pre-seizure electroencephalograms (EEGs) such as oscillating powers and high-frequency activities…

Applications · Statistics 2009-01-27 Li Qin , Yuedong Wang

Purpose: The understanding of brain activity, and in particular events such as epileptic seizures, lies on the characterisation of the dynamics of the neural networks. The theory of non-linear dynamics provides signal analysis techniques…

Medical Physics · Physics 2007-05-23 C. Silva , I. R. Pimentel , A. Andrade , J. P. Foreid , E. Ducla-Soares

Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…

Neurons and Cognition · Quantitative Biology 2019-06-19 Simona Olmi , Spase Petkoski , Maxime Guye , Fabrice Bartolomei , Viktor Jirsa

High-resolution neural datasets enable foundation models for the next generation of brain-computer interfaces and neurological treatments. The community requires rigorous benchmarks to discriminate between competing modeling approaches, yet…

We consider the electrical signals recorded from a subdural array of electrodes placed on the pial surface of the brain for chronic evaluation of epileptic patients before surgical resection. A simple and computationally fast method to…

Medical Physics · Physics 2007-11-18 Eshel Ben-Jacob , Stefano Boccaletti , Anna Pomyalov , Itamar Procaccia , Vernon L. Towle

This study proposes a Duffing oscillator based measurement framework for detecting frequency components associated with postsynaptic potential related activity in EEG recordings. The Duffing oscillator is employed as a nonlinear measurement…

Physics and Society · Physics 2026-01-14 Mahmut Akilli , Nazmi Yilmaz
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