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The emerging area of computational pathology (CPath) is ripe ground for the application of deep learning (DL) methods to healthcare due to the sheer volume of raw pixel data in whole-slide images (WSIs) of cancerous tissue slides. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-04-23 Jevgenij Gamper , Navid Alemi Koohbanani , Ksenija Benes , Simon Graham , Mostafa Jahanifar , Syed Ali Khurram , Ayesha Azam , Katherine Hewitt , Nasir Rajpoot

Cancer disease is one of the leading causes of death all over the world. Breast cancer, which is a common cancer disease especially in women, is quite common. The most important tool used for early detection of this cancer type, which…

Image and Video Processing · Electrical Eng. & Systems 2020-12-11 Ali Narin

Melanoma is the most aggressive form of skin cancer, and early detection can significantly increase survival rates and prevent cancer spread. However, developing reliable automated detection techniques is difficult due to the lack of…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 SangHyuk Kim , Edward Gaibor , Daniel Haehn

Extracting single-cell information from microscopy data requires accurate instance-wise segmentations. Obtaining pixel-wise segmentations from microscopy imagery remains a challenging task, especially with the added complexity of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-02 Christoph Reich , Tim Prangemeier , André O. Françani , Heinz Koeppl

There is a strong need for automated systems to improve diagnostic quality and reduce the analysis time in histopathology image processing. Automated detection and classification of pathological tissue characteristics with computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2019-11-22 Muhammed Talo

Publicly available, large-scale medical imaging datasets are crucial for developing and validating artificial intelligence models and conducting retrospective clinical research. However, datasets that combine functional and anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Le Xue , Gang Feng , Wenbo Zhang , Yichi Zhang , Lanlan Li , Shuqi Wang , Liling Peng , Sisi Peng , Xin Gao

Accurate detection and classification of nuclei in histopathology images are critical for diagnostic and research applications. We present KongNet, a multi-headed deep learning architecture featuring a shared encoder and parallel,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaqi Lv , Esha Sadia Nasir , Kesi Xu , Mostafa Jahanifar , Brinder Singh Chohan , Behnaz Elhaminia , Shan E Ahmed Raza

Advances in digital pathology and artificial intelligence (AI) offer promising opportunities for clinical decision support and enhancing diagnostic workflows. Previous studies already demonstrated AI's potential for automated Gleason…

We propose a novel automatic method for accurate segmentation of the prostate in T2-weighted magnetic resonance imaging (MRI). Our method is based on convolutional neural networks (CNNs). Because of the large variability in the shape, size,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-01 Davood Karimi , Golnoosh Samei , Yanan Shao , Septimiu Salcudean

Cancer remains one of the leading causes of morbidity and mortality worldwide. Comprehensive datasets that combine histopathological images with genetic and survival data across various tumour sites are essential for advancing computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Craig Myles , In Hwa Um , Craig Marshall , David Harris-Birtill , David J. Harrison

The account of mitotic cells is a key feature in tumor diagnosis. However, due to the variability of mitotic cell morphology, it is a highly challenging task to detect mitotic cells in tumor tissues. At the same time, although advanced deep…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Chen Yang , Wang Ziyue , Fang Zijie , Bian Hao , Zhang Yongbing

Prostate cancer is among the most common cancer in males and its heterogeneity is well known. Its early detection helps making therapeutic decision. There is no standard technique or procedure yet which is full-proof in predicting cancer…

Machine Learning · Computer Science 2018-12-18 Khalid Raza , Atif N Hasan

Cancer is one of the leading causes of death globally, and early diagnosis is crucial for patient survival. Deep learning algorithms have great potential for automatic cancer analysis. Artificial intelligence has achieved high performance…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Monika Górka , Daniel Jaworek , Marek Wodzinski

Segmentation of Prostate Cancer (PCa) tissues from Gleason graded histopathology images is vital for accurate diagnosis. Although deep learning (DL) based segmentation methods achieve state-of-the-art accuracy, they rely on large datasets…

Image and Video Processing · Electrical Eng. & Systems 2021-10-04 Dwarikanath Mahapatra

Tumor segmentation plays a critical role in histopathology, but it requires costly, fine-grained image-mask pairs annotated by pathologists. Thus, synthesizing histopathology data to expand the dataset is highly desirable. Previous works…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Hong Liu , Haosen Yang , Evi M. C. Huijben , Mark Schuiveling , Ruisheng Su , Josien P. W. Pluim , Mitko Veta

This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Kamyar Nazeri , Azad Aminpour , Mehran Ebrahimi

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

The astounding success made by artificial intelligence (AI) in healthcare and other fields proves that AI can achieve human-like performance. However, success always comes with challenges. Deep learning algorithms are data-dependent and…

Image and Video Processing · Electrical Eng. & Systems 2021-06-25 Johann Li , Guangming Zhu , Cong Hua , Mingtao Feng , BasheerBennamoun , Ping Li , Xiaoyuan Lu , Juan Song , Peiyi Shen , Xu Xu , Lin Mei , Liang Zhang , Syed Afaq Ali Shah , Mohammed Bennamoun

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Neel Kanwal , Roger Amundsen , Helga Hardardottir , Luca Tomasetti , Erling Sandoy Undersrud , Emiel A. M. Janssen , Kjersti Engan