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Time evolution equations for dynamical systems can often be derived from generating functionals. Examples are Newton's equations of motion in classical dynamics which can be generated within the Lagrange or the Hamiltonian formalism. We…

Neurons and Cognition · Quantitative Biology 2014-04-23 Claudius Gros

Drug discovery aims to find novel compounds with specified chemical property profiles. In terms of generative modeling, the goal is to learn to sample molecules in the intersection of multiple property constraints. This task becomes…

Machine Learning · Computer Science 2020-07-06 Wengong Jin , Regina Barzilay , Tommi Jaakkola

Predictive coding is the leading algorithmic framework to understand how expectations shape our experience of reality. Its main tenet is that sensory neurons encode prediction error: the residuals between a generative model of the sensory…

Neurons and Cognition · Quantitative Biology 2022-01-20 Alejandro Tabas , Katharina von Kriegstein

This paper presents our computational methodology using Genetic Algorithms (GA) for exploring the nature of RNA editing. These models are constructed using several genetic editing characteristics that are gleaned from the RNA editing system…

Neural and Evolutionary Computing · Computer Science 2007-05-23 C. Huang , L. M. Rocha

Large Language Models (LLMs) have demonstrated great promise in generating code, especially when used inside an evolutionary computation framework to iteratively optimize the generated algorithms. However, in some cases they fail to…

Neural and Evolutionary Computing · Computer Science 2025-03-24 Niki van Stein , Anna V. Kononova , Lars Kotthoff , Thomas Bäck

We introduce and motivate generative modeling as a central task for machine learning and provide a critical view of the algorithms which have been proposed for solving this task. We overview how generative modeling can be defined…

Machine Learning · Computer Science 2021-03-02 Alex Lamb

We introduce a language generative model framework for generating a styled paragraph based on a context sentence and a style reference example. The framework consists of a style encoder and a texts decoder. The style encoder extracts a…

Computation and Language · Computer Science 2020-03-03 Kuo-Hao Zeng , Mohammad Shoeybi , Ming-Yu Liu

This contribution is concerned with mathematical models for the dynamics of the genetic composition of populations evolving under recombination. Recombination is the genetic mechanism by which two parent individuals create the mixed type of…

Populations and Evolution · Quantitative Biology 2011-01-12 Ellen Baake

A good feature representation is a determinant factor to achieve high performance for many machine learning algorithms in terms of classification. This is especially true for techniques that do not build complex internal representations of…

Neural and Evolutionary Computing · Computer Science 2019-08-22 Noëlie Cherrier , Jean-Philippe Poli , Maxime Defurne , Franck Sabatié

Humans have an impressive ability to reason about new concepts and experiences from just a single example. In particular, humans have an ability for one-shot generalization: an ability to encounter a new concept, understand its structure,…

Machine Learning · Statistics 2016-05-26 Danilo Jimenez Rezende , Shakir Mohamed , Ivo Danihelka , Karol Gregor , Daan Wierstra

Molecular biology is a nanotechnology that works--it has worked for billions of years and in an amazing variety of circumstances. At its core is a system for acquiring, processing and communicating information that is universal, from…

Genomics · Quantitative Biology 2016-12-21 Apoorva D. Patel

Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

Biomolecules · Quantitative Biology 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

Generative control policies have recently unlocked major progress in robotics. These methods produce action sequences via diffusion or flow matching, with training data provided by demonstrations. But existing methods come with two key…

Robotics · Computer Science 2026-03-09 Vince Kurtz , Joel W. Burdick

Quantifying biomechanical properties of the human vasculature could deepen our understanding of cardiovascular diseases. Standard nonlinear regression in constitutive modeling requires considerable high-quality data and an explicit form of…

Machine Learning · Computer Science 2023-09-26 Minglang Yin , Zongren Zou , Enrui Zhang , Cristina Cavinato , Jay D. Humphrey , George Em Karniadakis

Most existing text generation models follow the sequence-to-sequence paradigm. Generative Grammar suggests that humans generate natural language texts by learning language grammar. We propose a syntax-guided generation schema, which…

Computation and Language · Computer Science 2023-06-27 Yafu Li , Leyang Cui , Jianhao Yan , Yongjing Yin , Wei Bi , Shuming Shi , Yue Zhang

Correctly capturing the symmetry transformations of data can lead to efficient models with strong generalization capabilities, though methods incorporating symmetries often require prior knowledge. While recent advancements have been made…

A grand challenge in machine learning is the development of computational algorithms that match or outperform humans in perceptual inference tasks that are complicated by nuisance variation. For instance, visual object recognition involves…

Machine Learning · Statistics 2015-04-03 Ankit B. Patel , Tan Nguyen , Richard G. Baraniuk

Generic generation and manipulation of text is challenging and has limited success compared to recent deep generative modeling in visual domain. This paper aims at generating plausible natural language sentences, whose attributes are…

Machine Learning · Computer Science 2018-09-14 Zhiting Hu , Zichao Yang , Xiaodan Liang , Ruslan Salakhutdinov , Eric P. Xing

Constrained generative modeling is fundamental to applications such as robotic control and autonomous driving, where models must respect physical laws and safety-critical constraints. In real-world settings, these constraints rarely take…

Machine Learning · Computer Science 2026-03-10 Xiaoxuan Liang , Saeid Naderiparizi , Yunpeng Liu , Berend Zwartsenberg , Frank Wood

In this work, a neural network is trained to replicate the code that trains it using only its own output as input. A paradigm for evolutionary self-replication in neural programs is introduced, where program parameters are mutated, and the…

Neural and Evolutionary Computing · Computer Science 2021-10-06 Samuel Schmidgall
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