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Progress in the biomedical field through the use of deep learning is hindered by the lack of interpretability of the models. In this paper, we study the RETAIN architecture for the forecasting of future glucose values for diabetic people.…

Machine Learning · Computer Science 2020-09-11 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Predicting the remaining useful life of machinery, infrastructure, or other equipment can facilitate preemptive maintenance decisions, whereby a failure is prevented through timely repair or replacement. This allows for a better decision…

Machine Learning · Computer Science 2019-07-22 Mathias Kraus , Stefan Feuerriegel

Clinical trials are critical for drug development but often suffer from expensive and inefficient patient recruitment. In recent years, machine learning models have been proposed for speeding up patient recruitment via automatically…

Machine Learning · Computer Science 2023-07-20 Brandon Theodorou , Cao Xiao , Jimeng Sun

Building trustworthy clinical AI systems requires not only accurate predictions but also transparent, biologically grounded explanations. We present \texttt{DiagnoLLM}, a hybrid framework that integrates Bayesian deconvolution, eQTL-guided…

Artificial Intelligence · Computer Science 2025-11-18 Bowen Xu , Xinyue Zeng , Jiazhen Hu , Tuo Wang , Adithya Kulkarni

The need for an intelligent, real-time spoilage prediction system has become critical in modern IoT-driven food supply chains, where perishable goods are highly susceptible to environmental conditions. Existing methods often lack…

Viewing the trajectory of a patient as a dynamical system, a recurrent neural network was developed to learn the course of patient encounters in the Pediatric Intensive Care Unit (PICU) of a major tertiary care center. Data extracted from…

Machine Learning · Statistics 2017-01-25 M Aczon , D Ledbetter , L Ho , A Gunny , A Flynn , J Williams , R Wetzel

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

Machine Learning · Computer Science 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Motivation: The importance of clinical data in understanding the pathophysiology of complex disorders has prompted the launch of multiple initiatives designed to generate patient-level data from various modalities. While these studies can…

Deriving interpretable prognostic features from deep-learning-based prognostic histopathology models remains a challenge. In this study, we developed a deep learning system (DLS) for predicting disease specific survival for stage II and III…

The high dimensionality and complexity of neuroimaging data necessitate large datasets to develop robust and high-performing deep learning models. However, the neuroimaging field is notably hampered by the scarcity of such datasets. In this…

Machine Learning · Computer Science 2023-12-15 Yutong Gao , Charles A. Ellis , Vince D. Calhoun , Robyn L. Miller

When developing AI systems that interact with humans, it is essential to design both a system that can understand humans, and a system that humans can understand. Most deep network based agent-modeling approaches are 1) not interpretable…

Machine Learning · Computer Science 2021-07-14 Ini Oguntola , Dana Hughes , Katia Sycara

As interpretability has been pointed out as the obstacle to the adoption of Deep Neural Networks (DNNs), there is an increasing interest in solving a transparency issue to guarantee the impressive performance. In this paper, we demonstrate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Woo-Jeoung Nam , Seong-Whan Lee

Conventional multimodal data integration methods provide a comprehensive assessment of the shared or unique structure within each individual data type but suffer from several limitations such as the inability to handle high-dimensional data…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Matthew Drexler , Benjamin Risk , James J Lah , Suprateek Kundu , Deqiang Qiu

The ubiquity of neural networks (NNs) in real-world applications, from healthcare to natural language processing, underscores their immense utility in capturing complex relationships within high-dimensional data. However, NNs come with…

Machine Learning · Computer Science 2024-07-08 Chang Yue , Niraj K. Jha

This paper presents a method for building patient-based networks that we call Precision disease networks, and its uses for predicting medical outcomes. Our methodology consists of building networks, one for each patient or case, that…

Quantitative Methods · Quantitative Biology 2019-11-01 J. Cabrera , D. Amaratunga , W. Kostis , J Kostis

In the field of high-performance computing (HPC), there has been recent exploration into the use of deep reinforcement learning for cluster scheduling (DRL scheduling), which has demonstrated promising outcomes. However, a significant…

Machine Learning · Computer Science 2024-03-26 Boyang Li , Zhiling Lan , Michael E. Papka

Conventional machine learning methods are predominantly designed to predict outcomes based on a single data type. However, practical applications may encompass data of diverse types, such as text, images, and audio. We introduce…

The lack of interpretability in the field of medical image analysis has significant ethical and legal implications. Existing interpretable methods in this domain encounter several challenges, including dependency on specific models,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Lijie Hu , Songning Lai , Wenshuo Chen , Hongru Xiao , Hongbin Lin , Lu Yu , Jingfeng Zhang , Di Wang

The human brain undergoes dynamic, potentially pathology-driven, structural changes throughout a lifespan. Longitudinal Magnetic Resonance Imaging (MRI) and other neuroimaging data are valuable for characterizing trajectories of change…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Agampreet Aulakh , Nils D. Forkert , Matthias Wilms

Developing inherently interpretable models for prediction has gained prominence in recent years. A subclass of these models, wherein the interpretable network relies on learning high-level concepts, are valued because of closeness of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Jayneel Parekh , Quentin Bouniot , Pavlo Mozharovskyi , Alasdair Newson , Florence d'Alché-Buc