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RNA-sequencing (RNA-seq) has become an exemplar technology in modern biology and clinical applications over the past decade. It has gained immense popularity in the recent years driven by continuous efforts of the bioinformatics community…

Motivation: Modern genomics laboratories generate massive volumes of sequencing data, often resulting in significant storage costs. Genomics storage consists of duplicate files, temporary processing files, and redundant intermediate data.…

Genomics · Quantitative Biology 2025-11-27 Margot Celerie , Andrew Oldfield , William Ritchie

In many applications such as copy number variant (CNV) detection, the goal is to identify short segments on which the observations have different means or medians from the background. Those segments are usually short and hidden in a long…

Methodology · Statistics 2020-03-30 Ning Hao , Yue Selena Niu , Feifei Xiao , Heping Zhang

This paper proposes a frequency-domain system identification method for learning low-order systems. The identification problem is formulated as the minimization of the l2 norm between the identified and measured frequency responses, with…

Systems and Control · Electrical Eng. & Systems 2025-11-18 Arya Honarpisheh , Mario Sznaier

In a typical multi-standard military communication receiver, fast and reliable spectrum sensing unit is required to extract the information of multiple channels (frequency bands) present in a wideband input signal. In this paper, an energy…

Information Theory · Computer Science 2016-08-16 S. J. Darak , A. P. Vinod , E. M-K. Lai

Weakly supervised learning algorithms are critical for scaling audio event detection to several hundreds of sound categories. Such learning models should not only disambiguate sound events efficiently with minimal class-specific annotation…

Sound · Computer Science 2020-05-05 Anurag Kumar , Vamsi Krishna Ithapu

LOFAR, the Low-Frequency Array, is a powerful new radio telescope operating between 10 and 240 MHz. LOFAR allows detailed sensitive high-resolution studies of the low-frequency radio sky. At the same time LOFAR also provides excellent short…

The LOw Frequency ARray - LOFAR - is a new radio interferometer designed with emphasis on flexible digital hardware instead of mechanical solutions. The array elements, so-called stations, are located in the Netherlands and in neighbouring…

Instrumentation and Methods for Astrophysics · Physics 2015-06-11 Maciej Serylak , Aris Karastergiou , Chris Williams , Wesley Armour , Michael Giles , the LOFAR Pulsar Working Group

Recent experiments indicate a connection between the low- and high-frequency noise affecting superconducting quantum systems. We explore the possibilities that both noises can be produced by one ensemble of microscopic modes, made up, e.g.,…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Alexander Shnirman , Gerd Schön , Ivar Martin , Yuriy Makhlin

A number of hardware upgrades for the Low-Frequency Array (LOFAR) are currently under development. These upgrades are collectively referred to as the LOFAR 2.0 upgrade. The first stage of LOFAR 2.0 will introduce a distributed clock signal…

Instrumentation and Methods for Astrophysics · Physics 2021-08-11 H. W. Edler , F. de Gasperin , D. Rafferty

Genomics has become an essential technology for surveilling emerging infectious disease outbreaks. A wide range of technologies and strategies for pathogen genome enrichment and sequencing are being used by laboratories worldwide, together…

We propose a frame-based representation of k-mers for detecting sequencing errors and rare variants in next generation sequencing data obtained from populations of closely related genomes. Frames are sets of non-orthogonal basis functions,…

Genomics · Quantitative Biology 2016-04-19 Raunaq Malhotra , Manjari Mukhopadhyay , Mary Poss , Raj Acharya

We present a novel method for efficiently producing semi-dense matches across images. Previous detector-free matcher LoFTR has shown remarkable matching capability in handling large-viewpoint change and texture-poor scenarios but suffers…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Yifan Wang , Xingyi He , Sida Peng , Dongli Tan , Xiaowei Zhou

Segmental duplications (SDs), or low-copy repeats (LCR), are segments of DNA greater than 1 Kbp with high sequence identity that are copied to other regions of the genome. SDs are among the most important sources of evolution, a common…

Data Structures and Algorithms · Computer Science 2018-09-25 Ibrahim Numanagić , Alim S. Gökkaya , Lillian Zhang , Bonnie Berger , Can Alkan , Faraz Hach

The novel coronavirus (SARS-CoV-2) has led to a pandemic. The current testing regime based on Reverse Transcription-Polymerase Chain Reaction for SARS-CoV-2 has been unable to keep up with testing demands, and also suffers from a relatively…

Reusing features in deep networks through dense connectivity is an effective way to achieve high computational efficiency. The recent proposed CondenseNet has shown that this mechanism can be further improved if redundant features are…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Le Yang , Haojun Jiang , Ruojin Cai , Yulin Wang , Shiji Song , Gao Huang , Qi Tian

Previous unsupervised domain adaptation methods did not handle the cross-domain problem from the perspective of frequency for computer vision. The images or feature maps of different domains can be decomposed into the low-frequency…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Zhaowen Li , Xu Zhao , Chaoyang Zhao , Ming Tang , Jinqiao Wang

Signal decomposition and multiscale signal analysis provide many useful tools for time-frequency analysis. We proposed a random feature method for analyzing time-series data by constructing a sparse approximation to the spectrogram. The…

Signal Processing · Electrical Eng. & Systems 2023-03-17 Nicholas Richardson , Hayden Schaeffer , Giang Tran

The estimation of the frequencies of multiple superimposed exponentials in noise is an important research problem due to its various applications from engineering to chemistry. In this paper, we propose an efficient and accurate algorithm…

Numerical Analysis · Mathematics 2016-05-05 Shanglin Ye , Elias Aboutanios

LOFAR is a low-frequency array distributed across several European countries. Each LOFAR station contains thousands of antennas and associated electronics, making monitoring and thorough testing of those components essential to ensuring…

Instrumentation and Methods for Astrophysics · Physics 2025-03-06 Jun Wang , M. J. Norden , P. Donker
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