English
Related papers

Related papers: Accelerating SARS-CoV-2 low frequency variant call…

200 papers

In light of the continuous transmission and evolution of SARS-CoV-2 coupled with a significant decline in clinical testing, there is a pressing need for scalable, cost-effective, long-term, passive surveillance tools to effectively monitor…

Next-generation sequencing (NGS) technologies have enabled affordable sequencing of billions of short DNA fragments at high throughput, paving the way for population-scale genomics. Genomics data analytics at this scale requires overcoming…

Databases · Computer Science 2019-10-11 Darryl Ho , Jialin Ding , Sanchit Misra , Nesime Tatbul , Vikram Nathan , Vasimuddin Md , Tim Kraska

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

During the SARS-CoV-2 pandemic, wastewater-based genomic surveillance (WWGS) emerged as an efficient viral surveillance tool that takes into account asymptomatic cases and can identify known and novel mutations and offers the opportunity to…

Significant volumes of knowledge have been accumulated in recent years linking subtle genetic variations to a wide variety of medical disorders from Cystic Fibrosis to mental retardation. Nevertheless, there are still great challenges in…

Genomics · Quantitative Biology 2016-11-17 Yaniv Erlich , Assaf Gordon , Michael Brand , Gregory J. Hannon , Partha P. Mitra

We calculate the utility of high-frequency squeezed-state enhanced two-frequency interferometry for low-frequency phase measurement. To use the high-frequency sidebands of the squeezed light, a two-frequency intense laser is used in the…

Quantum Physics · Physics 2015-05-27 Zehui Zhai , Jiangrui Gao

Radio frequency fingerprints (RFFs) enable secure wireless authentication but struggle in open-set scenarios with unknown devices and varying channels. Existing methods face challenges in generalization and incur high computational costs.…

Signal Processing · Electrical Eng. & Systems 2026-04-15 Mingxi Zhang , Renjie Xie , Jincheng Wang , Guyue Li , Wei Xu

More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by the generation of large volumes of viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies,…

Radio astronomy is entering the era of large surveys. This paper describes the plans for wide surveys with the LOw Frequency ARray (LOFAR) and their synergy with large surveys at higher frequencies (in particular in the 1-2 GHz band) that…

Cosmology and Nongalactic Astrophysics · Physics 2010-01-15 R. Morganti , H. Rottgering , I. Snellen , G. Miley , P. Barthel , P. Best , M. Bruggen , G. Brunetti , K. Chyzy , J. Conway , M. Jarvis , M. Lehnert

This paper describes a method to efficiently retrieve protein database sequences similar to a query sequence, while allowing for significant numbers of mutations. We call this method SEQR for SEQuence Retrieval. This approach increases the…

Genomics · Quantitative Biology 2018-11-05 David I. Hurwitz , Lianyi Han , Lewis Y. Geer

During the last couple of years, Recurrent Neural Networks (RNN) have reached state-of-the-art performances on most of the sequence modelling problems. In particular, the "sequence to sequence" model and the neural CRF have proved to be…

Computation and Language · Computer Science 2019-04-17 Marco Dinarelli , Loïc Grobol

Background: Recent epidemic outbreaks such as the SARS-CoV-2 pandemic and the mpox outbreak in 2022 have demonstrated the value of genomic sequencing data for tracking the origin and spread of pathogens. Laboratories around the globe…

With the rapid global spread of COVID-19, more and more data related to this virus is becoming available, including genomic sequence data. The total number of genomic sequences that are publicly available on platforms such as GISAID is…

Genomics · Quantitative Biology 2021-11-16 Sarwan Ali , Murray Patterson

Summary: The CoV-Spectrum website supports the identification of new SARS-CoV-2 variants of concern and the tracking of known variants. Its flexible amino acid and nucleotide mutation search allows querying of variants before they are…

Populations and Evolution · Quantitative Biology 2021-12-28 Chaoran Chen , Sarah Nadeau , Michael Yared , Philippe Voinov , Ning Xie , Cornelius Roemer , Tanja Stadler

Rapid, sensitive detection of biomolecules is important for improved testing methods for viruses as well as biomarkers and environmental hormones. For example, testing for SARS-CoV-2 is essential in the fight against the COVID-19 pandemic.…

The identification of siren sounds in urban soundscapes is a crucial safety aspect for smart vehicles and has been widely addressed by means of neural networks that ensure robustness to both the diversity of siren signals and the strong and…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-16 Stefano Damiano , Thomas Dietzen , Toon van Waterschoot

Genomic surveillance of SARS-CoV-2 has been instrumental in tracking the spread and evolution of the virus during the pandemic. The availability of SARS-CoV-2 molecular sequences isolated from infected individuals, coupled with phylodynamic…

Applications · Statistics 2021-08-31 Lorenzo Cappello , Jaehee Kim , Sifan Liu , Julia A. Palacios

The Low frequency analysis and recording (LOFAR) spectrum is one of the key features of the under water target, which can be used for underwater target recognition. However, the underwater environment noise is complicated and the…

Signal Processing · Electrical Eng. & Systems 2021-04-27 Jie Chen , Jie Liu , Chang Liu , Jian Zhang , Bing Han

A widely studied non-deterministic polynomial time (NP) hard problem lies in finding a route between the two nodes of a graph. Often meta-heuristics algorithms such as $A^{*}$ are employed on graphs with a large number of nodes. Here, we…

Machine Learning · Computer Science 2018-01-18 Alessandro Bay , Biswa Sengupta

The development of highly sensitive and rapid biosensing tools targeted to the highly contagious virus SARS-CoV-2 is critical to tackling the COVID-19 pandemic. Quantum sensors can play an important role, thanks to their superior…

Quantum Physics · Physics 2022-01-25 Changhao Li , Rouhollah Soleyman , Mohammad Kohandel , Paola Cappellaro