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We consider a continuum mechanical model of cell invasion through thin membranes. The model consists of a transmission problem for cell volume fraction complemented with continuity of stresses and mass flux across the surfaces of the…

Tissues and Organs · Quantitative Biology 2019-08-06 Mark A. J. Chaplain , Chiara Giverso , Tommaso Lorenzi , Luigi Preziosi

We consider a continuum mechanical model for the migration of multiple cell populations through parts of tissue separated by thin membranes. In this model, cells belonging to different populations may be characterised by different…

Analysis of PDEs · Mathematics 2021-09-28 Chiara Giverso , Tommaso Lorenzi , Luigi Preziosi

We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…

Analysis of PDEs · Mathematics 2015-07-29 Mimi Dai , Eduard Feireisl , Elisabetta Rocca , Giulio Schimperna , Maria Schonbek

We investigate two-phase flow in porous media and derive a two-scale model, which incorporates pore-scale phase distribution and surface tension into the effective behavior at the larger Darcy scale. The free-boundary problem at the pore…

Analysis of PDEs · Mathematics 2023-07-03 Mathis Kelm , Carina Bringedal , Bernd Flemisch

In this paper we study the rigorous sharp interface limit of a diffuse interface model related to the dynamics of tumor growth, when a parameter $\epsilon$, representing the interface thickness between the tumorous and non tumorous cells,…

Analysis of PDEs · Mathematics 2016-12-21 E. Rocca , R. Scala

In this paper we study the "stiff pressure limit" of the porous medium equation, where the initial density is a bounded, integrable function with a sufficient decay at infinity. Our particular model, introduced by Perthame-Quiros-Vazquez,…

Analysis of PDEs · Mathematics 2015-09-22 Inwon Kim , Norbert Pozar

The behavior of a conductive membrane in a static (DC) electric field is investigated theoretically. An effective zero-thickness model is constructed based on a Robin-type boundary condition for the electric potential at the membrane,…

Soft Condensed Matter · Physics 2015-05-14 Falko Ziebert , Martin Z. Bazant , David Lacoste

Biological, physical, medical, and numerical applications involving membrane problems on different scales are numerous. We propose an extension of the standard Turing theory to the case of two domains separated by a permeable membrane. To…

Analysis of PDEs · Mathematics 2022-03-04 Giorgia Ciavolella

We consider a degenerate partial differential equation arising in population dynamics, namely the porous medium equation with a bistable reaction term. We study its asymptotic behavior as a small parameter, related to the thickness of a…

Analysis of PDEs · Mathematics 2011-07-19 Matthieu Alfaro , Danielle Hilhorst

We investigate the sharp material interface limit of the Darcy-Boussinesq model for convection in layered porous media with diffused material interfaces, which allow a gradual transition of material parameters between different layers. We…

Analysis of PDEs · Mathematics 2025-04-25 Hongjie Dong , Xiaoming Wang

The mathematical modeling of tumor growth leads to singular stiff pressure law limits for porous medium equations with a source term. Such asymptotic problems give rise to free boundaries, which, in the absence of active motion, are…

Analysis of PDEs · Mathematics 2015-07-06 Inwon C. Kim , Benoit Perthame , Panagiotis E. Souganidis

We discuss the sharp interface limit of a diffuse interface model for a coupled Cahn-Hilliard--Darcy system that models tumor growth when a certain parameter $\varepsilon>0$, related to the interface thickness, tends to zero. In particular,…

Analysis of PDEs · Mathematics 2016-10-17 S. Melchionna , E. Rocca

We study the asymptotic behaviour of a system of nonlinear reaction--diffusion--advection equations in a domain consisting of two bulk regions connected via microscopic channels distributed within a thin membrane. Both the width of the…

Analysis of PDEs · Mathematics 2025-12-15 Lucas M. Fix , Gianna Götzmann , Malte A. Peter , Jan-F. Pietschmann

It is generally accepted that the effective velocity of a viscous flow over a porous bed satisfies the Beavers-Joseph slip law. To the contrary, in the case of a forced infiltration of a viscous fluid into a porous medium the interface law…

Analysis of PDEs · Mathematics 2023-07-19 Thomas Carraro , Christian Goll , Anna Marciniak-Czochra , Andro Mikelić

Effective interface conditions for a periodically voided thin layer separating two homogeneous bulk regions are derived for the elastic wave equation by taking the simultaneous limit of vanishing layer periodicity and layer thickness. The…

Analysis of PDEs · Mathematics 2026-03-30 Markus Gahn , Tanja Lochner , Malte A. Peter

We discuss the sharp interface limit of a diffuse interface model for a two-phase flow of two partly miscible viscous Newtonian fluids of different densities, when a certain parameter \epsilon>0 related to the interface thickness tends to…

Analysis of PDEs · Mathematics 2012-12-24 Helmut Abels , Daniel Lengeler

Several problems, issued from physics, biology or the medical science, lead to parabolic equations set in two sub-domains separated by a membrane with selective permeability to specific molecules. The corresponding boundary conditions,…

Analysis of PDEs · Mathematics 2022-06-27 Giorgia Ciavolella , Benoît Perthame

In this work, we derive asymptotic interface models for an elastic Muskat free boundary problem describing Darcy flow beneath an elastic membrane. In a weakly nonlinear regime of small interface steepness, we obtain nonlocal evolution…

Analysis of PDEs · Mathematics 2026-02-12 Diego Alonso-Orán , Rafael Granero-Belinchón

Boundary conditions at the interface between the free-flow region and the adjacent porous medium is a key issue for physically consistent modeling and accurate numerical simulation of flow and transport processes in coupled systems due to…

Numerical Analysis · Mathematics 2020-06-23 Elissa Eggenweiler , Iryna Rybak

In this work we consider an interface logistic problem where two populations live in two different regions, separated by a membrane or interface where it happens an interchange of flux. Thus, the two populations only interact or are coupled…

Analysis of PDEs · Mathematics 2024-02-15 Pablo Álvarez-Caudevilla , Cristina Brändle , Mónica Molina-Becerra , Antonio Suárez
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