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Longitudinal imaging analysis tracks disease progression and treatment response over time, providing dynamic insights into treatment efficacy and disease evolution. Radiomic features extracted from medical imaging can support the study of…

Applications · Statistics 2025-05-14 Isabella Cama , Michele Piana , Cristina Campi , Sara Garbarino

Demographic studies suggest that changes in the retinal vasculature geometry, especially in vessel width, are associated with the incidence or progression of eye-related or systemic diseases. To date, the main information source for width…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Fatmatulzehra Uslu , Anil Anthony Bharath

With the advent of structured data in the form of social networks, genetic circuits and protein interaction networks, statistical analysis of networks has gained popularity over recent years. Stochastic block model constitutes a classical…

Statistics Theory · Mathematics 2015-05-27 Debdeep Pati , Anirban Bhattacharya

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

We propose an interdisciplinary framework that combines Bayesian predictive inference, a well-established tool in Machine Learning, with Formal Methods rooted in the computer science community. Bayesian predictive inference allows for…

Computation · Statistics 2025-08-21 Laura Vana , Ennio Visconti , Laura Nenzi , Annalisa Cadonna , Gregor Kastner

Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Juan Eugenio Iglesias , Koen Van Leemput , Polina Golland , Anastasia Yendiki

Shape affects both the physical and chemical properties of a material. Characterizing the roughness, convexity, and general geometry of a material can yield information on its catalytic efficiency, solubility, elasticity, porosity, and…

Computational Engineering, Finance, and Science · Computer Science 2023-09-18 Alexander Smith , Steven Schilling , Prodromos Daoutidis

Variational methods are attractive for computing Bayesian inference for highly parametrized models and large datasets where exact inference is impractical. They approximate a target distribution - either the posterior or an augmented…

Computation · Statistics 2019-11-21 Michael Stanley Smith , Ruben Loaiza-Maya , David J. Nott

Statistical shape modeling (SSM) is an enabling quantitative tool to study anatomical shapes in various medical applications. However, directly using 3D images in these applications still has a long way to go. Recent deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2023-10-04 Abu Zahid Bin Aziz , Jadie Adams , Shireen Elhabian

Efficient and fast reconstruction of anatomical structures plays a crucial role in clinical practice. Minimizing retrieval and processing times not only potentially enhances swift response and decision-making in critical scenarios but also…

A shape filter is presented to repair segmentation results obtained in calcium imaging of neurons in vivo. This post-segmentation algorithm can automatically smooth the shapes obtained from a preliminary segmentation, while precluding the…

Image and Video Processing · Electrical Eng. & Systems 2018-06-04 Jie Wang , Zhongxiao Fu , Nasrin Sadeghzadehyazdi , Jonathan Kipnis , Scott T. Acton

We propose a geometric framework to assess sensitivity of Bayesian procedures to modeling assumptions based on the nonparametric Fisher-Rao metric. While the framework is general in spirit, the focus of this article is restricted to…

Methodology · Statistics 2014-04-28 Sebastian Kurtek , Karthik Bharath

A general Bayesian framework for model selection on random network models regarding their features is considered. The goal is to develop a principle Bayesian model selection approach to compare different fittable, not necessarily nested,…

Methodology · Statistics 2020-04-30 Papamichalis Marios

The assessment of imaging biomarkers is critical for advancing precision medicine and improving disease characterization. Despite the availability of methods to derive disease heterogeneity metrics in imaging studies, a robust framework for…

Parameter inference is a fundamental problem in data-driven modeling. Given observed data that is believed to be a realization of some parameterized model, the aim is to find parameter values that are able to explain the observed data. In…

Data Structures and Algorithms · Computer Science 2016-04-20 Carlo Albert , Simone Ulzega , Ruedi Stoop

Comparing mathematical models offers a means to evaluate competing scientific theories. However, exact methods of model calibration are not applicable to many probabilistic models which simulate high-dimensional spatio-temporal data.…

Quantitative Methods · Quantitative Biology 2026-01-13 Robert A McDonald , Helen M Byrne , Heather A Harrington , Thomas Thorne , Bernadette J Stolz

We present a Bayesian inference methodology for the estimation of orbital parameters on single-line spectroscopic binaries with astrometric data, based on the No-U-Turn sampler Markov chain Monte Carlo algorithm. Our approach is designed to…

Solar and Stellar Astrophysics · Physics 2022-04-27 Miguel Videla , Rene A. Mendez , Ruben M. Claveria , Jorge F. Silva , Marcos E. Orchard

Advances in imaging technology now provide us with detailed 3D data on gene expression patterns in developing embryos. This information can be used to build predictive mathematical models of embryogenesis. Current modelling approaches are,…

Quantitative Methods · Quantitative Biology 2014-06-11 Britta Velten , Erkan Uenal , Dagmar Iber

Computational cardiovascular models are promising tools for clinical decision support, particularly in complex conditions, such as intraoperative hypotension (IOH). IOH arises from different mechanisms, making treatment selection…

Medical Physics · Physics 2025-09-19 Jan-Niklas Thiel , Marko Zlicar , Ulrich Steinseifer , Borut Kirn , Michael Neidlin

With the introduction of spectral-domain optical coherence tomography (OCT), resulting in a significant increase in acquisition speed, the fast and accurate segmentation of 3-D OCT scans has become evermore important. This paper presents a…

Computer Vision and Pattern Recognition · Computer Science 2014-04-01 Fabian Rathke , Stefan Schmidt , Christoph Schnörr