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Joint Embedding Self-Supervised Learning (JE-SSL) has seen rapid developments in recent years, due to its promise to effectively leverage large unlabeled data. The development of JE-SSL methods was driven primarily by the search for ever…

Machine Learning · Computer Science 2023-03-06 Florian Bordes , Randall Balestriero , Pascal Vincent

The availability of large microarray data has led to a growing interest in biclustering methods in the past decade. Several algorithms have been proposed to identify subsets of genes and conditions according to different similarity measures…

Machine Learning · Statistics 2018-09-21 Amichai Painsky

Microarray techniques are widely used in Gene expression analysis. These techniques are based on discovering submatrices of genes that share similar expression patterns across a set of experimental conditions with coherence constraint.…

Quantitative Methods · Quantitative Biology 2020-01-27 Bilal Taher , Muhammad. H Fares , Saeed Jalili

Over recent years, there has been a rapid development of deep learning (DL) in both industry and academia fields. However, finding the optimal hyperparameters of a DL model often needs high computational cost and human expertise. To…

Neural and Evolutionary Computing · Computer Science 2022-08-24 Nan Li , Lianbo Ma , Guo Yu , Bing Xue , Mengjie Zhang , Yaochu Jin

As astronomical data grows in volume and complexity, the scalability of analysis software becomes increasingly important. At the same time, astrophysics analysis software relies heavily on open-source contributions, so languages and tools…

Instrumentation and Methods for Astrophysics · Physics 2024-02-01 Edward Berman , Jacqueline McCleary

The primary goal in cluster analysis is to discover natural groupings of objects. The field of cluster analysis is crowded with diverse methods that make special assumptions about data and address different scientific aims. Despite its…

Genomics · Quantitative Biology 2018-06-07 Gary K. Chen , Eric Chi , John Ranola , Kenneth Lange

Detection and differentiation of circulating tumor cells (CTCs) and non-CTCs in blood draws of cancer patients pose multiple challenges. While the gold standard relies on tedious manual evaluation of an automatically generated selection of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Hümeyra Husseini-Wüsthoff , Sabine Riethdorf , Andreas Schneeweiss , Andreas Trumpp , Klaus Pantel , Harriet Wikman , Maximilian Nielsen , René Werner

Gallbladder cancer (GBC) is the most frequent cause of disease among biliary tract neoplasms. Identifying the molecular mechanisms and biomarkers linked to GBC progression has been a significant challenge in scientific research. Few recent…

Personalized medicine remains a major challenge for scientists. The rapid growth of Machine learning and Deep learning has made them a feasible al- ternative for predicting the most appropriate therapy for individual patients. However, the…

Machine Learning · Computer Science 2025-06-10 Antonio Jesús Banegas-Luna , Horacio Pérez-Sánchez

Label-free cell classification is advantageous for supplying pristine cells for further use or examination, yet existing techniques frequently fall short in terms of specificity and speed. In this study, we address these limitations through…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Khayrul Islam , Ratul Paul , Shen Wang , Yuwen Zhao , Partho Adhikary , Qiying Li , Xiaochen Qin , Yaling Liu

We present Trixi.jl, a Julia package for adaptive high-order numerical simulations of hyperbolic partial differential equations. Utilizing Julia's strengths, Trixi.jl is extensible, easy to use, and fast. We describe the main design choices…

Mathematical Software · Computer Science 2022-01-19 Hendrik Ranocha , Michael Schlottke-Lakemper , Andrew R. Winters , Erik Faulhaber , Jesse Chan , Gregor J. Gassner

Bi-clustering refers to the task of finding sub-matrices (indexed by a group of columns and a group of rows) within a matrix of data such that the elements of each sub-matrix (data and features) are related in a particular way, for…

Machine Learning · Computer Science 2021-11-15 Kaijie Xu

Large language models (LLMs) have shown impressive few-shot generalization on many tasks via in-context learning (ICL). Despite their success in showing such emergent abilities, the scale and complexity of larger models also lead to…

Computation and Language · Computer Science 2025-06-03 Chengwei Qin , Wenhan Xia , Fangkai Jiao , Chen Chen , Yuchen Hu , Bosheng Ding , Ruirui Chen , Shafiq Joty

Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…

Quantitative Methods · Quantitative Biology 2024-06-13 Erin Craig , Timothy Keyes , Jolanda Sarno , Maxim Zaslavsky , Garry Nolan , Kara Davis , Trevor Hastie , Robert Tibshirani

Convolutional dictionary learning (CDL) estimates shift invariant basis adapted to multidimensional data. CDL has proven useful for image denoising or inpainting, as well as for pattern discovery on multivariate signals. As estimated…

Machine Learning · Computer Science 2019-01-29 Thomas Moreau , Alexandre Gramfort

Data discretization, also known as binning, is a frequently used technique in computer science, statistics, and their applications to biological data analysis. We present a new method for the discretization of real-valued data into a finite…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Elena S. Dimitrova , John J. McGee , Reinhard C. Laubenbacher

Clustering consists of partitioning data objects into subsets called clusters according to some similarity criteria. This paper addresses a generalization called quasi-clustering that allows overlapping of clusters, and which we link to…

Artificial Intelligence · Computer Science 2020-02-13 Fred Glover , Said Hanafi , Gintaras Palubeckis

Julia is a new language for writing data analysis programs that are easy to implement and run at high performance. Similarly, the Dynamic Distributed Dimensional Data Model (D4M) aims to clarify data analysis operations while retaining…

Mathematical Software · Computer Science 2016-12-13 Alexander Chen , Alan Edelman , Jeremy Kepner , Vijay Gadepally , Dylan Hutchison

Despite extensive safety measures, LLMs are vulnerable to adversarial inputs, or jailbreaks, which can elicit unsafe behaviors. In this work, we introduce bijection learning, a powerful attack algorithm which automatically fuzzes LLMs for…

Computation and Language · Computer Science 2025-05-13 Brian R. Y. Huang , Maximilian Li , Leonard Tang

Clustering is a commonly used method for exploring and analysing data where the primary objective is to categorise observations into similar clusters. In recent decades, several algorithms and methods have been developed for analysing…

Machine Learning · Computer Science 2021-02-17 Bryar A. Hassan , Tarik A. Rashid
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