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Human perception is inherently multimodal. We integrate, for instance, visual, proprioceptive and tactile information into one experience. Hence, multimodal learning is of importance for building robotic systems that aim at robustly…

Machine Learning · Computer Science 2024-11-04 Carlotta Langer , Yasmin Kim Georgie , Ilja Porohovoj , Verena Vanessa Hafner , Nihat Ay

Understanding relationships across multiple imaging modalities is central to neuroimaging research. We introduce the Integrative Variational Autoencoder (InVA), the first hierarchical VAE framework for image-on-image regression in…

Image and Video Processing · Electrical Eng. & Systems 2025-09-15 Bowen Lei , Yeseul Jeon , Rajarshi Guhaniyogi , Aaron Scheffler , Bani Mallick , Alzheimer's Disease Neuroimaging Initiatives

In this tutorial, we explore Variational Autoencoders (VAEs), an essential framework for unsupervised learning, particularly suited for high-dimensional datasets such as neuroimaging. By integrating deep learning with Bayesian inference,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz Sáez

Learning a robust Variational Autoencoder (VAE) is a fundamental step for many deep learning applications in medical image analysis, such as MRI synthesizes. Existing brain VAEs predominantly focus on single-modality data (i.e., T1-weighted…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Mingjie Li , Edward Kim , Yue Zhao , Ehsan Adeli , Kilian M. Pohl

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Cross-modal retrieval is to utilize one modality as a query to retrieve data from another modality, which has become a popular topic in information retrieval, machine learning, and database. How to effectively measure the similarity between…

Information Retrieval · Computer Science 2021-12-07 Jiwei Zhang , Yi Yu , Suhua Tang , Jianming Wu , Wei Li

Normative models in neuroimaging learn the brain patterns of healthy population distribution and estimate how disease subjects like Alzheimer's Disease (AD) deviate from the norm. Existing variational autoencoder (VAE)-based normative…

Machine Learning · Computer Science 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

Multiple modalities often co-occur when describing natural phenomena. Learning a joint representation of these modalities should yield deeper and more useful representations. Previous generative approaches to multi-modal input either do not…

Machine Learning · Computer Science 2018-11-13 Mike Wu , Noah Goodman

A new form of variational autoencoder (VAE) is developed, in which the joint distribution of data and codes is considered in two (symmetric) forms: ($i$) from observed data fed through the encoder to yield codes, and ($ii$) from latent…

Machine Learning · Computer Science 2017-11-21 Yunchen Pu , Weiyao Wang , Ricardo Henao , Liqun Chen , Zhe Gan , Chunyuan Li , Lawrence Carin

Variational autoencoders (VAEs) are used for transfer learning across various research domains such as music generation or medical image analysis. However, there is no principled way to assess before transfer which components to retrain or…

Machine Learning · Computer Science 2023-04-24 Lisa Bonheme , Marek Grzes

Cross-modal representation learning allows to integrate information from different modalities into one representation. At the same time, research on generative models tends to focus on the visual domain with less emphasis on other domains,…

Multimedia · Computer Science 2022-08-16 Maciej Żelaszczyk , Jacek Mańdziuk

Machine learning systems are often deployed in domains that entail data from multiple modalities, for example, phenotypic and genotypic characteristics describe patients in healthcare. Previous works have developed multimodal variational…

Machine Learning · Computer Science 2022-04-12 Jannik Wolff , Tassilo Klein , Moin Nabi , Rahul G. Krishnan , Shinichi Nakajima

The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns…

Quantitative Methods · Quantitative Biology 2017-08-25 Paolo Inglese , James L. Alexander , Anna Mroz , Zoltan Takats , Robert Glen

The variational autoencoder (VAE) is a generative model with continuous latent variables where a pair of probabilistic encoder (bottom-up) and decoder (top-down) is jointly learned by stochastic gradient variational Bayes. We first…

Machine Learning · Statistics 2016-04-19 Suwon Suh , Seungjin Choi

Given the notably increasing complexity of mathematical models to study realistic systems and their coupling to their environment that constrains their dynamics, both analytical approaches and numerical methods that build on these models,…

Quantum Physics · Physics 2019-11-11 I. Luchnikov , A. Ryzhov , P. -J. C. Stas , S. N. Filippov , H. Ouerdane

Elucidating the functional mechanisms of the primary visual cortex (V1) remains a fundamental challenge in systems neuroscience. Current computational models face two critical limitations, namely the challenge of cross-modal integration…

Neurons and Cognition · Quantitative Biology 2024-12-20 Yu Zhu , Bo Lei , Chunfeng Song , Wanli Ouyang , Shan Yu , Tiejun Huang

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

Variational Autoencoders (VAEs) provide a flexible and scalable framework for non-linear dimensionality reduction. However, in application domains such as genomics where data sets are typically tabular and high-dimensional, a black-box…

Machine Learning · Statistics 2020-03-10 Kaspar Märtens , Christopher Yau

Variational Autoencoder is a scalable method for learning latent variable models of complex data. It employs a clear objective that can be easily optimized. However, it does not explicitly measure the quality of learned representations. We…

Machine Learning · Computer Science 2020-05-29 Andriy Serdega , Dae-Shik Kim

We propose to apply non-linear representation learning to voxelwise rs-fMRI data. Learning the non-linear representations is done using a variational autoencoder (VAE). The VAE is trained on voxelwise rs-fMRI data and performs non-linear…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Eloy Geenjaar , Tonya White , Vince Calhoun
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