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Related papers: Active nematic defects and epithelial morphogenesi…

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Topological defects play a central role in the physics of many materials, including magnets, superconductors and liquid crystals. In active fluids, defects become autonomous particles that spontaneously propel from internal active stresses…

Soft Condensed Matter · Physics 2024-06-12 Suraj Shankar , Luca V. D. Scharrer , Mark J. Bowick , M. Cristina Marchetti

Active nematics are dense systems of rodlike particles that consume energy to drive motion at the level of the individual particles. They exist in natural systems like biological tissues and artificial materials such as suspensions of…

Soft Condensed Matter · Physics 2023-12-14 Yunrui Li , Zahra Zarei , Phu N. Tran , Yifei Wang , Aparna Baskaran , Seth Fraden , Michael F. Hagan , Pengyu Hong

The morphogenesis of cells and tissues involves an interplay between chemical signals and active forces on their surrounding surface layers. The complex interaction of hydrodynamics and material flows on such active surfaces leads to…

Cell Behavior · Quantitative Biology 2023-06-30 Sebastian Aland , Claudia Wohlgemuth

Cell shape changes are largely controlled by the actin cytoskeleton, a dynamic filament network beneath the plasma membrane. Several cell types can form extended free-standing protrusions not supported by an extracellular substrate or…

Soft Condensed Matter · Physics 2025-10-21 Kristiana Mihali , Dennis Wörthmüller , Pierre Sens

In confluent cell monolayers, patterns of cell forces and motion are systematically altered near topological defects in cell shape. In turn, defects have been proposed to alter cell density, extrusion, and invasion, but it remains unclear…

Biological Physics · Physics 2025-08-11 Pradip K. Bera , Molly McCord , Jun Zhang , Jacob Notbohm

The soil bacterium Myxococcus xanthus lives in densely packed groups that form dynamic three-dimensional patterns in response to environmental changes, such as droplet-like fruiting bodies during starvation. The development of these…

Biological Physics · Physics 2021-05-26 Katherine Copenhagen , Ricard Alert , Ned S. Wingreen , Joshua W. Shaevitz

Ordering configurations of a director field on a curved membrane induce stress. In this work, we present a theoretical framework to calculate the stress tensor and the torque as a consequence of the nematic ordering; we use the variational…

Soft Condensed Matter · Physics 2018-06-06 J. A. Santiago

We report numerical results for the hydrodynamics of inhomogeneous lyotropic and extensile active nematic gels. By simulating the coupled Cahn-Hilliard, Navier-Stokes, and Beris-Edwards equation for the evolution of the composition, flow…

Soft Condensed Matter · Physics 2023-01-06 Renato Assante , Dom Corbett , Davide Marenduzzo , Alexander Morozov

One of the defining features of active nematics is that above a critical activity the quiescent state becomes unstable to a distorted, flowing one. We show that spatial variations in activity can fundamentally change the nature of this…

Soft Condensed Matter · Physics 2025-12-15 Alexander J. H. Houston , Michael Grinfeld , Geoff McKay , Nigel J. Mottram

Due to the potential applications in biomedical engineering, it becomes more and more important to understand the process of engulfment and internalization of nanoparticles (NPs) by cell membranes. Despite the fact that the interaction…

Biological Physics · Physics 2023-12-12 Ke Xiao , Jing Li , Rui Ma , Chen-Xu Wu

Two-dimensional active nematics are often modeled using phenomenological continuum theories that describe the dynamics of the nematic director and fluid velocity through partial differential equations (PDEs). While these models provide a…

Active particles in anisotropic, viscoelastic fluids experience competing stresses which guide their trajectories. An aligned suspension of particles can trigger a hydrodynamic bend instability, but the elasticity of the fluid can drive…

Soft Condensed Matter · Physics 2025-06-10 Jingyi Li , Laurel Ohm , Saverio E. Spagnolie

As a method for controlling active materials, researchers have suggested designing patterns of activity on a substrate, which should guide the motion of topological defects. To investigate this concept, we model the behavior of a single…

Soft Condensed Matter · Physics 2021-02-10 Xingzhou Tang , Jonathan V. Selinger

We study the organization of topological defects in a system of nematogens confined to the two-dimensional sphere (S^2). We first perform Monte Carlo simulations of a fluid system of hard rods (spherocylinders) living in the tangent plane…

Soft Condensed Matter · Physics 2009-11-13 Homin Shin , Mark J. Bowick , Xiangjun Xing

We investigate the dynamics of mobile inclusions embedded in 2D active nematics. The interplay between the inclusion shape, the boundary-induced nematic order, and the autonomous flow powers the inclusion motion. Disks and achiral gears…

Soft Condensed Matter · Physics 2023-06-16 Sattvic Ray , Jie Zhang , Zvonimir Dogic

Monolayers of anisotropic cells exhibit long-ranged orientational order and topological defects. During the development of organisms, orientational order often influences morphogenetic events. However, the linkage between the mechanics of…

Soft Condensed Matter · Physics 2021-01-20 Carles Blanch-Mercader , Pau Guillamat , Aurélien Roux , Karsten Kruse

I put forward a continuum theory for active nematic gels, defined as fluids or suspensions of orientable rodlike objects endowed with active dynamics, that is based on symmetry arguments and compatibility with thermodynamics. The starting…

Soft Condensed Matter · Physics 2017-11-15 Stefano S Turzi

The effects of an electric field on the flow patterns and defect dynamics of two-dimensional active nematics are numerically investigated. We found that field-induced director reorientation causes anisotropic active turbulence characterized…

Soft Condensed Matter · Physics 2023-07-20 Yutaka Kinoshita , Nariya Uchida

Living cells establish long-range orientational order through collective alignment, giving rise to topological defects whose functional relevance is increasingly recognized in tissue organization and morphogenesis. Engineered topographical…

Soft Condensed Matter · Physics 2025-12-01 Prasoon Awasthi , Aniruddh Murali , Ellen Juel Pørtner , Adam Cohen Simonsen , Francesca Serra

The accumulation of self-propelled particles on repulsive barriers is a widely observed feature in active matter. Despite being implicated in a broad range of biological processes, from biofilm formation to cytoskeletal movement, wetting of…

Statistical Mechanics · Physics 2025-12-12 Noah Grodzinski , Michael E. Cates , Robert L. Jack