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High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Accurate cell segmentation is critical for biological and medical imaging studies. Although recent deep learning models have advanced this task, most methods are limited to generic cell segmentation, lacking the ability to differentiate…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Bisheng Wang , Jaime S. Cardoso , Lin Wu

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Abhay Shah , Michael Abramoff , Xiaodong Wu

We propose a probabilistic shape completion method extended to the continuous geometry of large-scale 3D scenes. Real-world scans of 3D scenes suffer from a considerable amount of missing data cluttered with unsegmented objects. The problem…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Dongsu Zhang , Changwoon Choi , Inbum Park , Young Min Kim

Medical image segmentation is crucial for accurate clinical diagnoses, yet it faces challenges such as low contrast between lesions and normal tissues, unclear boundaries, and high variability across patients. Deep learning has improved…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Houze Liu , Tong Zhou , Yanlin Xiang , Aoran Shen , Jiacheng Hu , Junliang Du

Medical researchers and clinicians often need to perform novel segmentation tasks on a set of related images. Existing methods for segmenting a new dataset are either interactive, requiring substantial human effort for each image, or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Hallee E. Wong , Jose Javier Gonzalez Ortiz , John Guttag , Adrian V. Dalca

To segment 4K or 6K ultra high-resolution images needs extra computation consideration in image segmentation. Common strategies, such as down-sampling, patch cropping, and cascade model, cannot address well the balance issue between…

Computer Vision and Pattern Recognition · Computer Science 2025-02-24 Tiancheng Shen , Yuechen Zhang , Lu Qi , Jason Kuen , Xingyu Xie , Jianlong Wu , Zhe Lin , Jiaya Jia

Segmentation maps of medical images annotated by medical experts contain rich spatial information. In this paper, we propose to decompose annotation maps to learn disentangled and richer feature transforms for segmentation problems in…

Image and Video Processing · Electrical Eng. & Systems 2019-06-10 Yizhe Zhang , Michael T. C. Ying , Danny Z. Chen

Given the prevalence of 3D medical imaging technologies such as MRI and CT that are widely used in diagnosing and treating diverse diseases, 3D segmentation is one of the fundamental tasks of medical image analysis. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-10 Yuhui Zhang , Shih-Cheng Huang , Zhengping Zhou , Matthew P. Lungren , Serena Yeung

Hyperspectral image analysis has become an important topic widely researched by the remote sensing community. Classification and segmentation of such imagery help understand the underlying materials within a scanned scene, since…

Computer Vision and Pattern Recognition · Computer Science 2020-12-02 Jakub Nalepa , Michal Myller , Yasuteru Imai , Ken-ichi Honda , Tomomi Takeda , Marek Antoniak

Automatic instance segmentation is a problem that occurs in many biomedical applications. State-of-the-art approaches either perform semantic segmentation or refine object bounding boxes obtained from detection methods. Both suffer from…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Long Chen , Martin Strauch , Dorit Merhof

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

Microscopy imaging plays a vital role in understanding many biological processes in development and disease. The recent advances in automation of microscopes and development of methods and markers for live cell imaging has led to rapid…

Computer Vision and Pattern Recognition · Computer Science 2017-05-10 Saad Ullah Akram , Juho Kannala , Lauri Eklund , Janne Heikkilä

It is well-known in image processing that computational cost increases rapidly with the number and dimensions of the images to be processed. Several fields, such as medical imaging, routinely use numerous very large images, which might also…

Computer Vision and Pattern Recognition · Computer Science 2016-05-24 Fares Al-Qunaieer , Hamid R. Tizhoosh , Shahryar Rahnamayan

Deep learning-based segmentation and classification are crucial to large-scale biomedical imaging, particularly for 3D data, where manual analysis is impractical. Although many methods exist, selecting suitable models and tuning parameters…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 David Exler , Joaquin Eduardo Urrutia Gómez , Martin Krüger , Maike Schliephake , John Jbeily , Mario Vitacolonna , Rüdiger Rudolf , Markus Reischl

Localizing desired objects from remote sensing images is of great use in practical applications. Referring image segmentation, which aims at segmenting out the objects to which a given expression refers, has been extensively studied in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Zhenghang Yuan , Lichao Mou , Yuansheng Hua , Xiao Xiang Zhu

Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured environments. While deep learning approaches have proven useful…

Quantitative Methods · Quantitative Biology 2021-01-08 Tim Prangemeier , Christian Wildner , André O. Françani , Christoph Reich , Heinz Koeppl

Instance segmentation is essential for numerous computer vision applications, including robotics, human-computer interaction, and autonomous driving. Currently, popular models bring impressive performance in instance segmentation by…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Cuong Manh Hoang

In this paper, we propose an approach to the unsupervised segmentation of images using Markov Random Field. The proposed approach is based on the idea of Bit Plane Slicing. We use the planes as initial labellings for an ensemble of…

Computer Vision and Pattern Recognition · Computer Science 2014-10-29 Balint Antal , Bence Remenyik , Andras Hajdu