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This paper studies the inference of the regression coefficient matrix under multivariate response linear regressions in the presence of hidden variables. A novel procedure for constructing confidence intervals of entries of the coefficient…

Methodology · Statistics 2022-01-21 Xin Bing , Wei Cheng , Huijie Feng , Yang Ning

Multiple hypothesis testing (MHT) frequently arises in scientific inquiries, and concurrent testing of multiple hypotheses inflates the risk of Type-I errors or false positives, rendering MHT corrections essential. This paper addresses MHT…

This paper presents a selective survey of recent developments in statistical inference and multiple testing for high-dimensional regression models, including linear and logistic regression. We examine the construction of confidence…

Methodology · Statistics 2023-01-26 T. Tony Cai , Zijian Guo , Yin Xia

We develop a highly scalable optimization method called "hierarchical group-thresholding" for solving a multi-task regression model with complex structured sparsity constraints on both input and output spaces. Despite the recent emergence…

Machine Learning · Statistics 2012-08-16 Seunghak Lee , Eric P. Xing

Two common concerns raised in analyses of randomized experiments are (i) appropriately handling issues of non-compliance, and (ii) appropriately adjusting for multiple tests (e.g., on multiple outcomes or subgroups). Although simple…

Methodology · Statistics 2016-05-25 Joseph J. Lee , Laura Forastiere , Luke Miratrix , Natesh S. Pillai

Hierarchical models with gamma hyperpriors provide a flexible, sparse-promoting framework to bridge $L^1$ and $L^2$ regularizations in Bayesian formulations to inverse problems. Despite the Bayesian motivation for these models, existing…

Methodology · Statistics 2021-11-30 Shiv Agrawal , Hwanwoo Kim , Daniel Sanz-Alonso , Alexander Strang

Multiple hypothesis testing is a significant problem in nearly all neuroimaging studies. In order to correct for this phenomena, we require a reliable estimate of the Family-Wise Error Rate (FWER). The well known Bonferroni correction…

Computation · Statistics 2015-02-17 Chris Hinrichs , Vamsi K Ithapu , Qinyuan Sun , Sterling C Johnson , Vikas Singh

Response-adaptive designs allow the randomization probabilities to change during the course of a trial based on cumulated response data, so that a greater proportion of patients can be allocated to the better performing treatments. A major…

Methodology · Statistics 2020-06-03 David S. Robertson , James M. S. Wason

Meta-analysis represents a widely accepted approach for evaluating the accuracy of diagnostic tools in clinical and psychological investigations. This paper investigates the applicability of multinomial tree models recently suggested in the…

Methodology · Statistics 2024-05-29 Annamaria Guolo

It is imperative to discern the relationships between multiple time series for accurate forecasting. In particular, for stock prices, components are often divided into groups with the same characteristics, and a model that extracts…

Machine Learning · Computer Science 2023-05-16 Ryo Umagami , Yu Ono , Yusuke Mukuta , Tatsuya Harada

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

Precision matrix, which is the inverse of covariance matrix, plays an important role in statistics, as it captures the partial correlation between variables. Testing the equality of two precision matrices in high dimensional setting is a…

Methodology · Statistics 2018-10-23 Mingjuan Zhang , Yong He , Cheng Zhou , Xinsheng Zhang

In a split conformal framework with $K$ classes, a calibration sample of $n$ labeled examples is observed for inference on the label of a new unlabeled example. We explore the setting where a `batch' of $m$ independent such unlabeled…

Methodology · Statistics 2025-03-19 Ulysse Gazin , Ruth Heller , Etienne Roquain , Aldo Solari

Bayesian hierarchical linear models provide a natural framework to analyze nested and clustered data. Classical estimation with Markov chain Monte Carlo produces well calibrated posterior distributions but becomes computationally expensive…

Methodology · Statistics 2025-12-16 Cristian Parra-Aldana , Juan Sosa

Heterogeneity is an unwanted variation when analyzing aggregated datasets from multiple sources. Though different methods have been proposed for heterogeneity adjustment, no systematic theory exists to justify these methods. In this work,…

Methodology · Statistics 2016-02-18 Jianqing Fan , Han Liu , Weichen Wang , Ziwei Zhu

Inference in deep neural networks can be computationally expensive, and networks capable of anytime inference are important in mscenarios where the amount of compute or quantity of input data varies over time. In such networks the inference…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Adria Ruiz , Jakob Verbeek

When comparing multiple groups in clinical trials, we are not only interested in whether there is a difference between any groups but rather the location. Such research questions lead to testing multiple individual hypotheses. To control…

While there is substantial need for dependence models in higher dimensions, most existing models quickly become rather restrictive and barely balance parsimony and flexibility. Hierarchical constructions may improve on that by grouping…

Methodology · Statistics 2013-10-11 Eike Christian Brechmann

It is difficult to use subsampling with variational inference in hierarchical models since the number of local latent variables scales with the dataset. Thus, inference in hierarchical models remains a challenge at large scale. It is…

Machine Learning · Computer Science 2021-11-08 Abhinav Agrawal , Justin Domke

Correlated observations are ubiquitous phenomena in a plethora of scientific avenues. Tackling this dependence among test statistics has been one of the pertinent problems in simultaneous inference. However, very little literature exists…

Statistics Theory · Mathematics 2024-11-20 Monitirtha Dey