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Recent advancements in quantum annealing hardware and numerous studies in this area suggests that quantum annealers have the potential to be effective in solving unconstrained binary quadratic programming problems. Naturally, one may desire…

Quantum Physics · Physics 2019-03-01 Sahar Karimi , Pooya Ronagh

Efficient optimisation of black-box problems that comprise both continuous and categorical inputs is important, yet poses significant challenges. We propose a new approach, Continuous and Categorical Bayesian Optimisation (CoCaBO), which…

Machine Learning · Statistics 2020-08-11 Binxin Ru , Ahsan S. Alvi , Vu Nguyen , Michael A. Osborne , Stephen J Roberts

Quantum annealing is a type of analog computation that aims to use quantum mechanical fluctuations in search of optimal solutions of QUBO (quadratic unconstrained binary optimization) or, equivalently, Ising problems. Since NP-hard problems…

Quantum Physics · Physics 2023-04-14 Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

Quantum annealing has emerged as a powerful tool for solving combinatorial optimization problems efficiently, making use of the principles of quantum mechanics. Companies are increasingly investing in the market of quantum computers,…

Quantum Physics · Physics 2025-09-29 Lorenzo Mazzei , Giada Beccari , Mirko Laruina , Marco Cococcioni

Bayesian optimization (BO) is a powerful approach for seeking the global optimum of expensive black-box functions and has proven successful for fine tuning hyper-parameters of machine learning models. However, BO is practically limited to…

Machine Learning · Statistics 2020-09-28 Riccardo Moriconi , Marc P. Deisenroth , K. S. Sesh Kumar

An important task in multi-objective optimization is generating the Pareto front -- the set of all Pareto-optimal compromises among multiple objective functions applied to the same set of variables. Since this task can be computationally…

Quantum Physics · Physics 2025-11-04 Andrew D. King

The global optimization of a high-dimensional black-box function under black-box constraints is a pervasive task in machine learning, control, and engineering. These problems are challenging since the feasible set is typically non-convex…

Machine Learning · Computer Science 2021-03-02 David Eriksson , Matthias Poloczek

Black box optimization (BBO) focuses on optimizing unknown functions in high-dimensional spaces. In many applications, sampling the unknown function is expensive, imposing a tight sample budget. Ongoing work is making progress on reducing…

Machine Learning · Computer Science 2025-07-29 Rajalaxmi Rajagopalan , Yu-Lin Wei , Romit Roy Choudhury

This paper proposes a quasi-binary encoding based algorithm for solving a specific quadratic optimization models with discrete variables, in the quantum approximate optimization algorithm (QAOA) framework. The quadratic optimization model…

Quantum Physics · Physics 2024-01-25 Bingren Chen , Hanqing Wu , Haomu Yuan , Lei Wu , Xin Li

Modern quantum annealers can find high-quality solutions to combinatorial optimisation objectives given as quadratic unconstrained binary optimisation (QUBO) problems. Unfortunately, obtaining suitable QUBO forms in computer vision remains…

Analytical and practical evidence indicates the advantage of quantum computing solutions over classical alternatives. Quantum-based heuristics relying on the variational quantum eigensolver (VQE) and the quantum approximate optimization…

Quantum Physics · Physics 2023-01-05 Sarthak Gupta , Vassilis Kekatos

The major advances in quantum computing over the last few decades have sparked great interest in applying it to solve the most challenging computational problems in a wide variety of areas. One of the most pronounced domains here are…

Quantum Physics · Physics 2024-04-11 Andreas Sturm , Bharadwaj Mummaneni , Leon Rullkötter

The Quantum Approximate Optimization Algorithm (QAOA) is a highly promising variational quantum algorithm that aims to solve combinatorial optimization problems that are classically intractable. This comprehensive review offers an overview…

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

Quantum annealing (QA) has been proposed as a quantum enhanced optimization heuristic exploiting tunneling. Here, we demonstrate how finite range tunneling can provide considerable computational advantage. For a crafted problem designed to…

In discrete-variable black-box optimization, the number of candidate solutions grows combinatorially, while each evaluation is often expensive. Therefore, it is important to identify promising solutions efficiently within a limited number…

Quantum Physics · Physics 2026-05-12 Reo Shikanai , Masayuki Ohzeki

Constrained combinatorial optimization with strict linear constraints underpins applications in drug discovery, power grids, logistics, and finance, yet remains computationally demanding for classical algorithms, especially at large scales.…

Quantum Physics · Physics 2026-04-07 Yajie Hao , Qiming Ding , Xiao Yuan , Xiaoting Wang

We propose and compare Constraint Programming (CP) and Quantum Annealing (QA) approaches for rolling stock assignment optimisation considering necessary maintenance tasks. In the CP approach, we model the problem with an Alldifferent…

Artificial Intelligence · Computer Science 2023-09-26 Patricia Bickert , Cristian Grozea , Ronny Hans , Matthias Koch , Christina Riehn , Armin Wolf

Quantum Annealing (QA) uses quantum fluctuations to search for a global minimum of an optimization-type problem faster than classical computers. To meet the demand for future internet traffic and mitigate the spectrum scarcity, this work…

Information Theory · Computer Science 2023-01-11 Eldar Gabdulsattarov , Khaled Rabie , Xingwang Li , Galymzhan Nauryzbayev

Quantum computing is an emerging field on the multidisciplinary interface between physics, engineering, and computer science with the potential to make a large impact on computational intelligence (CI). The aim of this paper is to introduce…

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