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High-throughput microarray and sequencing technology have been used to identify disease subtypes that could not be observed otherwise by using clinical variables alone. The classical unsupervised clustering strategy concerns primarily the…

Methodology · Statistics 2020-07-23 Peng Liu , Yusi Fang , Zhao Ren , Lu Tang , George C. Tseng

The task of clustering unlabeled time series and sequences entails a particular set of challenges, namely to adequately model temporal relations and variable sequence lengths. If these challenges are not properly handled, the resulting…

Machine Learning · Statistics 2019-02-19 Daniel J. Trosten , Andreas S. Strauman , Michael Kampffmeyer , Robert Jenssen

We aim to develop clustering models to obtain behavioral representations from continuous multimodal mobile sensing data towards relapse prediction tasks. The identified clusters could represent different routine behavioral trends related to…

Machine Learning · Computer Science 2022-02-22 Joanne Zhou , Bishal Lamichhane , Dror Ben-Zeev , Andrew Campbell , Akane Sano

This paper proposes an noise type classification aided attention-based neural network approach for monaural speech enhancement. The network is constructed based on a previous work by introducing a noise classification subnetwork into the…

Sound · Computer Science 2021-06-01 Lu Ma , Song Yang , Yaguang Gong , Zhongqin Wu

Topological Data Analysis (TDA) has been successfully used for various tasks in signal/image processing, from visualization to supervised/unsupervised classification. Often, topological characteristics are obtained from persistent homology…

Sound · Computer Science 2023-10-11 Guillem Bonafos , Jean-Marc Freyermuth , Pierre Pudlo , Samuel Tronçon , Arnaud Rey

Many multi-variate time series obtained in the natural sciences and engineering possess a repetitive behavior, as for instance state-space trajectories of industrial machines in discrete automation. Recovering the times of recurrence from…

Computational Geometry · Computer Science 2025-05-20 Simon Schindler , Elias Steffen Reich , Saverio Messineo , Simon Hoher , Stefan Huber

Over the last two decades, topological data analysis (TDA) has emerged as a very powerful data analytic approach which can deal with various data modalities of varying complexities. One of the most commonly used tools in TDA is persistent…

Methodology · Statistics 2025-12-08 Anass El Yaagoubi Bourakna , Moo K. Chung , Hernando Ombao

In this paper we develop a novel Topological Data Analysis (TDA) approach for studying graph representations of time series of dynamical systems. Specifically, we show how persistent homology, a tool from TDA, can be used to yield a…

Chaotic Dynamics · Physics 2020-01-28 Audun Myers , Elizabeth Munch , Firas A. Khasawneh

This paper proposes a practical approach for automatic sleep stage classification based on a multi-level feature learning framework and Recurrent Neural Network (RNN) classifier using heart rate and wrist actigraphy derived from a wearable…

Machine Learning · Statistics 2017-11-03 Xin Zhang , Weixuan Kou , Eric I-Chao Chang , He Gao , Yubo Fan , Yan Xu

Time series forecasting has gained lots of attention recently; this is because many real-world phenomena can be modeled as time series. The massive volume of data and recent advancements in the processing power of the computers enable…

Machine Learning · Computer Science 2021-04-01 Manie Tadayon , Yumi Iwashita

Based on audio recordings made once a month during the first 12 months of a child's life, we propose a new method for clustering this set of vocalizations. We use a topologically augmented representation of the vocalizations, employing two…

Epilepsy is a neurological disorder characterized by recurrent seizures affecting more than 70 million people worldwide. Often, an individual with epilepsy is more likely to experience subsequent seizures following an initial seizure, a…

We present a novel application of LSTM recurrent neural networks to multilabel classification of diagnoses given variable-length time series of clinical measurements. Our method outperforms a strong baseline on a variety of metrics.

Machine Learning · Computer Science 2017-03-23 Zachary C. Lipton , David C. Kale , Randall C. Wetzel

Globally, the incidence of heart failure is increasing, and its principal treatment involves drug therapy. However, widespread non-adherence to therapies is prevalent among heart failure patients and often results in worsening health…

Applications · Statistics 2023-12-29 Nicole Fontana , Laura Savaré , Francesca Ieva

This paper applies statistical learning techniques to an observational Quantified-Self (QS) study to build a descriptive model of sleep quality. A total of 472 days of my sleep data was collected with an Oura ring and combined with…

Quantitative Methods · Quantitative Biology 2021-05-17 Gianluca Truda

Interacting, self-propelled particles such as epithelial cells can dynamically self-organize into complex multicellular patterns, which are challenging to classify without a priori information. Classically, different phases and phase…

Quantitative Methods · Quantitative Biology 2021-01-19 Dhananjay Bhaskar , William Y. Zhang , Ian Y. Wong

Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a chronic breathing disorder caused by a blockage in the upper airways. Snoring is a prominent symptom of OSAHS, and previous studies have attempted to identify the obstruction site of…

Sound · Computer Science 2023-07-26 Li Xiao , Xiuping Yang , Xinhong Li , Weiping Tu , Xiong Chen , Weiyan Yi , Jie Lin , Yuhong Yang , Yanzhen Ren

Identifying a patient's key problems over time is a common task for providers at the point care, yet a complex and time-consuming activity given current electric health records. To enable a problem-oriented summarizer to identify a…

Applications · Statistics 2020-03-26 Gal Levy-Fix , Jason Zucker , Konstantin Stojanovic , Noémie Elhadad

We present a topological framework for analysing neural time series that integrates Transfer Entropy (TE) with directed Persistent Homology (PH) to characterize information flow in spiking neural systems. TE quantifies directional influence…

Neurons and Cognition · Quantitative Biology 2025-08-27 Dylan Peek , Siddharth Pritam , Matthew P. Skerritt , Stephan Chalup

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

Sound · Computer Science 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam