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Medical data often exhibit characteristics that make cluster analysis particularly challenging, such as missing values, outliers, and cluster features like skewness. Typically, such data would need to be preprocessed -- by cleaning outliers…

Methodology · Statistics 2025-12-16 Jason Pillay , Cristina Tortora , Antonio Punzo , Andriette Bekker

While machine learning (ML) includes a valuable array of tools for analyzing biomedical data, significant time and expertise is required to assemble effective, rigorous, and unbiased pipelines. Automated ML (AutoML) tools seek to facilitate…

Persistent homology is a method for probing topological properties of point clouds and functions. The method involves tracking the birth and death of topological features (2000) as one varies a tuning parameter. Features with short…

Internet of Things (IoT) enabled wearable sensors for health monitoring are widely used to reduce the cost of personal healthcare and improve quality of life. The sleep apnea-hypopnea syndrome, characterized by the abnormal reduction or…

Machine Learning · Computer Science 2021-06-18 Arlene John , Barry Cardiff , Deepu John

Clustering time-series data in healthcare is crucial for clinical phenotyping to understand patients' disease progression patterns and to design treatment guidelines tailored to homogeneous patient subgroups. While rich temporal dynamics…

Machine Learning · Computer Science 2023-02-27 Yuchao Qin , Mihaela van der Schaar , Changhee Lee

Obstructive Sleep Apnea (OSA) is a highly prevalent but inconspicuous disease that seriously jeopardizes the health of human beings. Polysomnography (PSG), the gold standard of detecting OSA, requires multiple specialized sensors for signal…

Signal Processing · Electrical Eng. & Systems 2021-01-11 Guanhua Ye , Hongzhi Yin , Tong Chen , Hongxu Chen , Lizhen Cui , Xiangliang Zhang

Sleep apnea (SA) is a type of sleep disorder characterized by snoring and chronic sleeplessness, which can lead to serious conditions such as high blood pressure, heart failure, and cardiomyopathy (enlargement of the muscle tissue of the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Anh-Tu Nguyen , Thao Nguyen , Huy-Khiem Le , Huy-Hieu Pham , Cuong Do

Detecting obstructive sleep apnea (OSA) is essential for diagnosing and managing sleep health. Traditionally, this involves clinical settings with hardly accessible processes. We propose that the automated detection of OSA events is…

Sleep staging is a challenging task, typically manually performed by sleep technologists based on electroencephalogram and other biosignals of patients taken during overnight sleep studies. Recent work aims to leverage automated algorithms…

Machine Learning · Computer Science 2024-11-13 Shashank Manjunath , Hau-Tieng Wu , Aarti Sathyanarayana

Precision medicine tailors treatments to individual patient characteristics, which is especially valuable for conditions like obstructive sleep apnea (OSA), where treatment responses vary widely. Traditional trials often overlook subgroup…

Applications · Statistics 2025-03-20 Lara Maleyeff , Shirin Golchi , Erica E. M. Moodie , R. John Kimoff

Snoring is extremely common in the general population and when irregular may indicate the presence of obstructive sleep apnea. We analyze the overnight sequence of wave packets --- the snore sound --- recorded during full polysomnography in…

Sleep plays a vital role in human health, both mental and physical. Sleep disorders like sleep apnea are increasing in prevalence, with the rapid increase in factors like obesity. Sleep apnea is most commonly treated with Continuous…

Signal Processing · Electrical Eng. & Systems 2018-10-30 Karan Aggarwal , Swaraj Khadanga , Shafiq R. Joty , Louis Kazaglis , Jaideep Srivastava

The ability to assess sleep at home, capture sleep stages, and detect the occurrence of apnea (without on-body sensors) simply by analyzing the radio waves bouncing off people's bodies while they sleep is quite powerful. Such a capability…

Accurately diagnosing sleep disorders is essential for clinical assessments and treatments. Polysomnography (PSG) has long been used for detection of various sleep disorders. In this research, electrocardiography (ECG) and electromayography…

Machine Learning · Computer Science 2021-11-12 Delaram Jarchi , Javier Andreu-Perez , Mehrin Kiani , Oldrich Vysata , Jiri Kuchynka , Ales Prochazka , Saeid Sane

We introduce an entropy-based classification method for pairs of sequences (ECPS) for quantifying mutual dependencies in heart rate and beat-to-beat blood pressure recordings. The purpose of the method is to build a classifier for data in…

Recently, growing health awareness, novel methods allow individuals to monitor sleep at home. Utilizing sleep sounds offers advantages over conventional methods like smartwatches, being non-intrusive, and capable of detecting various…

Machine Learning · Computer Science 2024-10-18 Shintaro Tamai , Masayuki Numao , Ken-ichi Fukui

A novel procedure to perform fuzzy clustering of multivariate time series generated from different dependence models is proposed. Different amounts of dissimilarity between the generating models or changes on the dynamic behaviours over…

Methodology · Statistics 2021-09-09 Ángel López-Oriona , José A. Vilar , Pierpaolo-D'Urso

Patients with sleep disorders can better manage their lifestyle if they know about their special situations. Detection of such sleep disorders is usually possible by analyzing a number of vital signals that have been collected from the…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Mohamadreza Jafaryani , Saeed Khorram , Vahid Pourahmadi , Minoo Shahbazi

Clustering multivariate time series (MTS) is challenging due to non-stationary cross-dependencies, noise contamination, and gradual or overlapping state boundaries. We introduce a robust fuzzy clustering framework in the spectral domain…

Applications · Statistics 2025-11-03 Ziling Ma , Mara Sherlin Talento , Ying Sun , Hernando Ombao

We develop the hierarchical cluster coherence (HCC) method for brain signals, a procedure for characterizing connectivity in a network by clustering nodes or groups of channels that display high level of coordination as measured by…

Applications · Statistics 2017-11-21 Carolina Euan , Ying Sun , Hernando Ombao