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Reliable identification of molecular biomarkers is essential for accurate patient stratification. While state-of-the-art machine learning approaches for sample classification continue to push boundaries in terms of performance, most of…

Molecular Networks · Quantitative Biology 2019-11-07 Matteo Manica , Joris Cadow , Roland Mathis , María Rodríguez Martínez

Varying power-infeed from converter-based generation units introduces great uncertainty on system parameters such as inertia and damping. As a consequence, system operators face increasing challenges in performing dynamic security…

Systems and Control · Electrical Eng. & Systems 2021-04-16 Jochen Stiasny , George S. Misyris , Spyros Chatzivasileiadis

Many physical systems are described by partial differential equations (PDEs), and solving these equations and estimating their coefficients or boundary conditions (BCs) from observational data play a crucial role in understanding the…

Machine Learning · Computer Science 2025-07-18 Tomohisa Okazaki

This work proposes a solution for the problem of training physics-informed networks under partial integro-differential equations. These equations require an infinite or a large number of neural evaluations to construct a single residual for…

Machine Learning · Computer Science 2024-06-12 Ehsan Saleh , Saba Ghaffari , Timothy Bretl , Luke Olson , Matthew West

Reconstructing fields from sparsely observed data is an ill-posed problem that arises in many engineering and science applications. Here, we investigate the use of physics-informed neural networks (PINNs) to reconstruct complete…

Fluid Dynamics · Physics 2024-10-11 Nagahiro Ohashi , Leslie K. Hwang , Beomjin Kwon

Current modeling approaches for hydrological modeling often rely on either physics-based or data-science methods, including Machine Learning (ML) algorithms. While physics-based models tend to rigid structure resulting in unrealistic…

Machine Learning · Statistics 2021-04-23 Pravin Bhasme , Jenil Vagadiya , Udit Bhatia

In this paper, we highlight three issues that limit performance of machine learning on biomedical images, and tackle them through 3 case studies: 1) Interactive Machine Learning (IML): we show how IML can drastically improve exploration…

Computer Vision and Pattern Recognition · Computer Science 2019-02-18 Naimul Mefraz Khan , Nabila Abraham , Ling Guan

Recently, a class of machine learning methods called physics-informed neural networks (PINNs) has been proposed and gained prevalence in solving various scientific computing problems. This approach enables the solution of partial…

Computational Engineering, Finance, and Science · Computer Science 2023-11-06 Chen Xu , Ba Trung Cao , Yong Yuan , Günther Meschke

A data-driven model augmentation framework, referred to as Weakly-coupled Integrated Inference and Machine Learning (IIML), is presented to improve the predictive accuracy of physical models. In contrast to parameter calibration, this work…

Computational Engineering, Finance, and Science · Computer Science 2022-07-25 Vishal Srivastava , Valentin Sulzer , Peyman Mohtat , Jason B. Siegel , Karthik Duraisamy

Physics-informed machine learning (PIML) is crucial in modern traffic flow modeling because it combines the benefits of both physics-based and data-driven approaches. In conventional PIML, physical information is typically incorporated by…

Machine Learning · Computer Science 2025-09-23 Yuan-Zheng Lei , Yaobang Gong , Dianwei Chen , Yao Cheng , Xianfeng Terry Yang

Physics-informed neural networks approach the approximation of differential equations by directly incorporating their structure and given conditions in a loss function. This enables conditions like, e.g., invariants to be easily added…

Machine Learning · Computer Science 2025-08-20 Santosh Humagain , Toni Schneidereit

With the increases in computational power and advances in machine learning, data-driven learning-based methods have gained significant attention in solving PDEs. Physics-informed neural networks (PINNs) have recently emerged and succeeded…

Machine Learning · Computer Science 2023-02-07 Namgyu Kang , Byeonghyeon Lee , Youngjoon Hong , Seok-Bae Yun , Eunbyung Park

This paper proposes a gradient descent based optimization method that relies on automatic differentiation for the computation of gradients. The method uses tools and techniques originally developed in the field of artificial neural networks…

Systems and Control · Electrical Eng. & Systems 2023-09-29 Georg Kordowich , Johann Jaeger

Scientific Machine Learning (SciML) integrates physics and data into the learning process, offering improved generalization compared with purely data-driven models. Despite its potential, applications of SciML in prognostics remain limited,…

Machine Learning · Computer Science 2025-11-04 Ibai Ramirez , Jokin Alcibar , Joel Pino , Mikel Sanz , David Pardo , Jose I. Aizpurua

Physics-informed deep learning has drawn tremendous interest in recent years to solve computational physics problems, whose basic concept is to embed physical laws to constrain/inform neural networks, with the need of less data for training…

Fluid Dynamics · Physics 2020-11-24 Chengping Rao , Hao Sun , Yang Liu

Latent state space models are a fundamental and widely used tool for modeling dynamical systems. However, they are difficult to learn from data and learned models often lack performance guarantees on inference tasks such as filtering and…

Machine Learning · Computer Science 2016-05-31 Wen Sun , Arun Venkatraman , Byron Boots , J. Andrew Bagnell

While machine learning (ML) has found multiple applications in photonics, traditional "black box" ML models typically require prohibitively large training data sets. Generation of such data, as well as the training processes themselves,…

We present a new efficient hybrid parameter estimation method based on the idea, that if nonlinear dynamic models are stated in terms of a system of equations that is linear in terms of the parameters, then regularized ordinary least…

Confined ion transport is involved in nanoporous ionic systems. However, it is challenging to mechanistically predict its electrical characteristics for rational system design and performance evaluation using electrical circuit model due to…

Mesoscale and Nanoscale Physics · Physics 2024-06-03 Hualin Zhan , Richard Sandberg , Fan Feng , Qinghua Liang , Ke Xie , Lianhai Zu , Dan Li , Jefferson Zhe Liu

Machine learning (ML) has emerged as a powerful tool for tackling complex regression and classification tasks, yet its success often hinges on the quality of training data. This study introduces an ML paradigm inspired by domain knowledge…

Machine Learning · Computer Science 2025-01-10 Mohsen Rashki