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Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

Explainable AI (XAI) seeks to transform black-box algorithmic processes into transparent ones, enhancing trust in AI applications across various sectors such as education. This review aims to examine the various definitions of XAI within…

Computers and Society · Computer Science 2025-04-07 Zaid M. Altukhi , Sojen Pradhan

There are concerns about the reliability and safety of artificial intelligence (AI) based on sub-symbolic neural networks because its decisions cannot be explained explicitly. This is the black box problem of modern AI. At the same time,…

Artificial Intelligence · Computer Science 2024-05-21 V. L. Kalmykov , L. V. Kalmykov

Smart home systems are gaining popularity as homeowners strive to enhance their living and working environments while minimizing energy consumption. However, the adoption of artificial intelligence (AI)-enabled decision-making models in…

Human-Computer Interaction · Computer Science 2024-07-30 Md Shajalal , Alexander Boden , Gunnar Stevens , Delong Du , Dean-Robin Kern

Despite AI's significant growth, its "black box" nature creates challenges in generating adequate trust. Thus, it is seldom utilized as a standalone unit in IoT high-risk applications, such as critical industrial infrastructures, medical…

Artificial Intelligence · Computer Science 2022-05-04 Maede Zolanvari , Zebo Yang , Khaled Khan , Raj Jain , Nader Meskin

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

The rapid growth of research in explainable artificial intelligence (XAI) follows on two substantial developments. First, the enormous application success of modern machine learning methods, especially deep and reinforcement learning, which…

Artificial Intelligence · Computer Science 2020-05-06 S. Atakishiyev , H. Babiker , N. Farruque , R. Goebel1 , M-Y. Kima , M. H. Motallebi , J. Rabelo , T. Syed , O. R. Zaïane

AI is becoming increasingly common across different domains. However, as sophisticated AI-based systems are often black-boxed, rendering the decision-making logic opaque, users find it challenging to comply with their recommendations.…

Artificial Intelligence · Computer Science 2024-06-19 Niklas Kühl , Christian Meske , Maximilian Nitsche , Jodie Lobana

Explainable artificial intelligence (xAI) is seen as a solution to making AI systems less of a black box. It is essential to ensure transparency, fairness, and accountability, which are especially paramount in the financial sector. The aim…

Artificial Intelligence · Computer Science 2021-11-08 Ouren Kuiper , Martin van den Berg , Joost van der Burgt , Stefan Leijnen

Artificial intelligence now outperforms humans in several scientific and engineering tasks, yet its internal representations often remain opaque. In this Perspective, we argue that explainable artificial intelligence (XAI), combined with…

Artificial Intelligence · Computer Science 2026-02-17 Ricardo Vinuesa , Steven L. Brunton , Gianmarco Mengaldo

Recent applications of autonomous agents and robots, such as self-driving cars, scenario-based trainers, exploration robots, and service robots have brought attention to crucial trust-related challenges associated with the current…

Robotics · Computer Science 2022-09-26 Fatai Sado , Chu Kiong Loo , Wei Shiung Liew , Matthias Kerzel , Stefan Wermter

With Artificial Intelligence (AI) becoming ubiquitous in every application domain, the need for explanations is paramount to enhance transparency and trust among non-technical users. Despite the potential shown by Explainable AI (XAI) for…

Human-Computer Interaction · Computer Science 2024-02-05 Aditya Bhattacharya

The lack of explainability of Artificial Intelligence (AI) is one of the first obstacles that the industry and regulators must overcome to mitigate the risks associated with the technology. The need for eXplainable AI (XAI) is evident in…

Computers and Society · Computer Science 2025-02-24 Georgios Pavlidis

Computer Vision, and hence Artificial Intelligence-based extraction of information from images, has increasingly received attention over the last years, for instance in medical diagnostics. While the algorithms' complexity is a reason for…

Human-Computer Interaction · Computer Science 2020-07-14 Christian Meske , Enrico Bunde

The black-box nature of artificial intelligence (AI) models has been the source of many concerns in their use for critical applications. Explainable Artificial Intelligence (XAI) is a rapidly growing research field that aims to create…

Cryptography and Security · Computer Science 2023-06-13 Gaith Rjoub , Jamal Bentahar , Omar Abdel Wahab , Rabeb Mizouni , Alyssa Song , Robin Cohen , Hadi Otrok , Azzam Mourad

Explainable Artificial Intelligence (XAI) is an emerging area of research in the field of Artificial Intelligence (AI). XAI can explain how AI obtained a particular solution (e.g., classification or object detection) and can also answer…

Machine Learning · Computer Science 2021-07-16 Prashant Gohel , Priyanka Singh , Manoranjan Mohanty

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

This study critically examines the commonly held assumption that explicability in artificial intelligence (AI) systems inherently boosts user trust. Utilizing a meta-analytical approach, we conducted a comprehensive examination of the…

Artificial Intelligence · Computer Science 2025-04-18 Zahra Atf , Peter R. Lewis

Explainability has been a challenge in AI for as long as AI has existed. With the recently increased use of AI in society, it has become more important than ever that AI systems would be able to explain the reasoning behind their results…

Artificial Intelligence · Computer Science 2020-09-30 Kary Främling