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Networks are ubiquitous in biology and computational approaches have been largely investigated for their inference. In particular, supervised machine learning methods can be used to complete a partially known network by integrating various…

Machine Learning · Computer Science 2014-04-25 Marie Schrynemackers , Louis Wehenkel , M. Madan Babu , Pierre Geurts

The comprehensive characterization of the structure of complex networks is essential to understand the dynamical processes which guide their evolution. The discovery of the scale-free distribution and the small world property of real…

Computational Physics · Physics 2009-11-13 Paulino R. Villas Boas , Francisco A. Rodrigues , Gonzalo Travieso , Luciano da F. Costa

In this work we study the problem of network morphism, an effective learning scheme to morph a well-trained neural network to a new one with the network function completely preserved. Different from existing work where basic morphing types…

Machine Learning · Computer Science 2017-01-13 Tao Wei , Changhu Wang , Chang Wen Chen

Several approaches were proposed to describe the geomorphology of drainage networks and the abiotic/biotic factors determining their morphology. There is an intrinsic complexity of the explicit qualification of the morphological variations…

Deep generative networks trained via maximum likelihood on a natural image dataset like CIFAR10 often assign high likelihoods to images from datasets with different objects (e.g., SVHN). We refine previous investigations of this failure at…

Machine Learning · Computer Science 2020-11-03 Robin Tibor Schirrmeister , Yuxuan Zhou , Tonio Ball , Dan Zhang

Phylogenetic networks are a generalization of phylogenetic trees that allow for representation of reticulate evolution. Recently, a space of unrooted phylogenetic networks was introduced, where such a network is a connected graph in which…

Populations and Evolution · Quantitative Biology 2017-03-09 Andrew Francis , Katharina Huber , Vincent Moulton , Taoyang Wu

Complex networks are a powerful modeling tool, allowing the study of countless real-world systems. They have been used in very different domains such as computer science, biology, sociology, management, etc. Authors have been trying to…

Social and Information Networks · Computer Science 2014-02-04 Burcu Kantarcı , Vincent Labatut

Phylogenetic networks play an important role in evolutionary biology as, other than phylogenetic trees, they can be used to accommodate reticulate evolutionary events such as horizontal gene transfer and hybridization. Recent research has…

Populations and Evolution · Quantitative Biology 2024-03-19 Linda Knüver , Mareike Fischer , Marc Hellmuth , Kristina Wicke

Reticulate evolution can be modelled using phylogenetic networks. Tree-based networks, which are one of the more general classes of phylogenetic networks, have recently gained eminence for its ability to represent evolutionary histories…

Populations and Evolution · Quantitative Biology 2024-07-15 Joan Carles Pons , Pau Vives López , Yukihiro Murakami , Leo Van Iersel

Network reconstruction lies at the heart of phylogenetic research. Two well studied classes of phylogenetic networks include tree-child networks and level-$k$ networks. In a tree-child network, every non-leaf node has a child that is a tree…

Combinatorics · Mathematics 2019-07-23 Yukihiro Murakami , Leo van Iersel , Remie Janssen , Mark Jones , Vincent Moulton

In a previous work, we gave a metric on the class of semibinary tree-sibling time consistent phylogenetic networks that is computable in polynomial time; in particular, the problem of deciding if two networks of this kind are isomorphic is…

Populations and Evolution · Quantitative Biology 2009-02-27 Gabriel Cardona , Merce Llabres , Francesc Rossello , Gabriel Valiente

Phylogenetic network is an evolutionary model that uses a rooted directed acyclic graph (instead of a tree) to model an evolutionary history of species in which reticulate events (e.g., hybrid speciation or horizontal gene transfer)…

Populations and Evolution · Quantitative Biology 2023-12-01 Yufeng Wu , Louxin Zhang

This paper studies the relationship between undirected (unrooted) and directed (rooted) phylogenetic networks. We describe a polynomial-time algorithm for deciding whether an undirected nonbinary phylogenetic network, given the locations of…

Data Structures and Algorithms · Computer Science 2023-10-02 Katharina T. Huber , Leo van Iersel , Remie Janssen , Mark Jones , Vincent Moulton , Yukihiro Murakami , Charles Semple

Hierarchical Bayesian networks and neural networks with stochastic hidden units are commonly perceived as two separate types of models. We show that either of these types of models can often be transformed into an instance of the other, by…

Machine Learning · Computer Science 2015-01-23 Diederik P. Kingma , Max Welling

Biological networks have evolved to be highly functional within uncertain environments while remaining extremely adaptable. One of the main contributors to the robustness and evolvability of biological networks is believed to be their…

Molecular Networks · Quantitative Biology 2008-02-14 Arend Hintze , Christoph Adami

Phylogenetic networks are often constructed by merging multiple conflicting phylogenetic signals into a directed acyclic graph. It is interesting to explore whether a network constructed in this way induces biologically-relevant…

Populations and Evolution · Quantitative Biology 2017-07-13 Steven Kelk , Fabio Pardi , Celine Scornavacca , Leo van Iersel

One of the central questions in the theory of deep learning is to understand how neural networks learn hierarchical features. The ability of deep networks to extract salient features is crucial to both their outstanding generalization…

Machine Learning · Computer Science 2025-04-03 Eshaan Nichani , Alex Damian , Jason D. Lee

Naturally occurring networks exhibit quantitative features revealing underlying growth mechanisms. Numerous network mechanisms have recently been proposed to reproduce specific properties such as degree distributions or clustering…

Quantitative Methods · Quantitative Biology 2009-11-10 Manuel Middendorf , Etay Ziv , Chris Wiggins

Modeling biological networks serves as both a major goal and an effective tool of systems biology in studying mechanisms that orchestrate the activities of gene products in cells. Biological networks are context specific and dynamic in…

Molecular Networks · Quantitative Biology 2014-02-20 Ye Tian , Bai Zhang , Eric P. Hoffman , Robert Clarke , Zhen Zhang , Ie-Ming Shih , Jianhua Xuan , David M. Herrington , Yue Wang

In this paper, we develop a graphical modeling framework for the inference of networks across multiple sample groups and data types. In medical studies, this setting arises whenever a set of subjects, which may be heterogeneous due to…

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