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Membrane proteins serve a wide range of vital roles in the functioning of living organisms. Compared to other classes of proteins, determining membrane protein structures remains a challenge, in large part due to the difficulty in…

We present a simple and computationally efficient coarse-grained and solvent-free model for simulating lipid bilayer membranes. In order to be used in concert with particle-based reaction-diffusion simulations, the model is purely based on…

Biological Physics · Physics 2018-01-31 Mohsen Sadeghi , Thomas R. Weikl , Frank Noé

Soluble alpha-amylases play an important role in the catabolism of polysaccharides. In this work, we show that the enzyme can interact with the lipid membrane and further alter its mechanical properties. Vesicle fluctuation spectroscopy is…

A new method is proposed for the analysis of specular and off-specular reflectivity from supported lipid bilayers. Both thermal fluctuations and the "static" roughness induced by the substrate are carefully taken into account. Examples from…

Soft Condensed Matter · Physics 2009-10-08 Linda Malaquin , Thierry Charitat , Jean Daillant

We address the atomistic nature of the longitudinal static friction against sliding of graphene nanoribbons (GNRs) deposited on gold, a system whose structural and mechanical properties have been recently the subject of intense experimental…

Mesoscale and Nanoscale Physics · Physics 2017-07-07 Lorenzo Gigli , Nicola Manini , Andrea Benassi , Erio Tosatti , Andrea Vanossi , Roberto Guerra

We develop theory and computational methods to investigate particle inclusions embedded within curved lipid bilayer membranes. We consider the case of spherical lipid vesicles where inclusion particles are coupled through (i) intramembrane…

Soft Condensed Matter · Physics 2023-02-28 Jon Karl Sigurdsson , Paul J. Atzberger

Gold nanoparticles (AuNPs) have been shown to possess properties beneficial for the treatment of cancerous tumors by acting as radiosensitizers for both photon and ion radiation. Blood circulation time is usually increased by coating the…

Atomic and Molecular Clusters · Physics 2016-09-21 Kaspar Haume , Nigel J. Mason , Andrey Solov'yov

Investigating the cellular internalization pathways of single molecules or single nano-objects is important to understanding cell-matter interactions and to applications in drug delivery and discovery. Imaging and tracking the motion of…

Biological Physics · Physics 2015-06-04 Guosong Hong , Justin Z. Wu , Joshua T. Robinson , Hailiang Wang , Bo Zhang , Hongjie Dai

Successful assembly of suspended nanoscale rod-like particles depends on fundamental phenomena controlling rotational and translational diffusion. Despite the significant developments in fluidic fabrication of nanostructured materials, the…

Soft Condensed Matter · Physics 2018-01-25 Christophe Brouzet , Nitesh Mittal , L. Daniel Söderberg , Fredrik Lundell

Wrinkling is a ubiquitous phenomenon in two-dimensional membranes. In particular, in the large-scale growth of graphene on metallic substrates, high densities of wrinkles are commonly observed. Despite their prevalence and potential impact…

Mesoscale and Nanoscale Physics · Physics 2012-07-13 Wenjuan Zhu , Tony Low , Vasili Perebeinos , Ageeth A. Bol , Yu Zhu , Hugen Yan , Jerry Tersoff , Phaedon Avouris

This paper investigates experimentally and numerically the dynamics of solid particles during the layer inversion of binary solid-liquid fluidized beds in narrow tubes. Layer inversion can happen in solid classifiers and biological…

Fluid Dynamics · Physics 2020-04-02 Fernando David Cúñez Benalcázar , Erick de Moraes Franklin

The equilibrium distance between two lipid bilayers stable in bulk water and in proximity of a substrate was investigated. Samples consisted of a homogeneous lipid bilayer, floating near an identical bilayer deposited on the hydrophilic…

Soft Condensed Matter · Physics 2007-05-23 Giovanna Fragneto , Thierry Charitat , Edith Bellet-Amalric , Robert Cubitt , Francois Graner

It is well known that lipid membranes respond to a threshold transmembrane electric field through a reversible mechanism called electroporation, where hydrophilic water pores form across the membrane, an effect widely used in biological…

Soft Condensed Matter · Physics 2023-04-17 Di Jin , Yu Zhang , Jacob Klein

It was recently discovered that friction between surfaces bearing phosphatidylcholine (PC) lipid bilayers can be increased by two orders of magnitude or more via an externally-applied electric field, and that this increase is fully…

Soft Condensed Matter · Physics 2024-09-26 Di Jin , Jacob Klein

Several methods now exist to solvate lipid bilayer discoids at the scale of tens of nanometres. Due to their size, such nanodiscoids have a comparatively large boundary-to-area ratio, making them unusually well-suited to probing the effects…

Soft Condensed Matter · Physics 2019-04-02 R. G. Morris , T. R. Dafforn , M. S. Turner

Electronic structures of the zigzag bilayer graphite nanoribbons(Z-BGNR) with various ribbon width $N$ are studied within the tight binding approximation. Neglecting the inter-layer hopping amplitude $\gamma_4$, which is an order of…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 Jun-Won Rhim , Kyungsun Moon

Efforts to modulate the electronic properties of atomically thin crystalline nanoribbons requires precise control over their morphology. Here, we perform atomistic simulations on freestanding graphene nanoribbons (GNRs) to first identify…

Mesoscale and Nanoscale Physics · Physics 2011-07-21 Hailong Wang , Moneesh Upmanyu

In this study, we present a first-principles investigation of the electronic and optical properties of gallium nitride (GaN) bilayers, focusing on the influence of interlayer sliding and spacing. In contrast to the earlier studies on…

Mesoscale and Nanoscale Physics · Physics 2025-06-03 Heeju Kim , Gunn Kim

Nanogaps are ubiquitous across science, confining molecules and thus changing chemistries which influence many areas such as catalysis, corrosion, photochemistry, and sensing. However in ambient conditions, it is unclear how water solvates…

Morphological transitions of phase separation associated with the asymmetry of lipid composition were investigated using micrometer-sized vesicles of lipid bilayers made from a lipid mixture. The complete macro-phase-separated morphology…

Biological Physics · Physics 2015-04-14 Shunsuke F. Shimobayashi , Masatoshi Ichikawa , Takashi Taniguchi