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In many applications, different populations are compared using data that are sampled in a biased manner. Under sampling biases, standard methods that estimate the difference between the population means yield unreliable inferences. Here we…

Statistics Theory · Mathematics 2019-11-12 Dave Zachariah , Petre Stoica

Participation incentives is a well-known issue inhibiting randomized controlled trials (RCTs) in medicine, as well as a potential cause of user dissatisfaction for RCTs in online platforms. We frame this issue as a non-standard…

Computer Science and Game Theory · Computer Science 2026-01-13 Yingkai Li , Aleksandrs Slivkins

Search engines intentionally influence user behavior by picking and ranking the list of results. Users engage with the highest results both because of their prominent placement and because they are typically the most relevant documents.…

Information Retrieval · Computer Science 2022-07-14 Richard Demsyn-Jones

Many biological, psychological and economic experiments have been designed where an organism or individual must choose between two options that have the same expected reward but differ in the variance of reward received. In this way,…

Quantitative Methods · Quantitative Biology 2018-09-20 Jared M. Field , Michael B. Bonsall

Identifying subgroups, which respond differently to a treatment, both in terms of efficacy and safety, is an important part of drug development. A well-known challenge in exploratory subgroup analyses is the small sample size in the…

Computation · Statistics 2016-06-28 Marius Thomas , Björn Bornkamp

Online advertising platforms host hundreds of thousands of A/B tests, but the platform's delivery algorithm routes each creative to the audience it predicts will engage. Every two-arm test therefore conflates the creative's effect with the…

Econometrics · Economics 2026-05-25 Pallavi Pal , Anjana Susarla

Significant evidence has become available that emphasizes the importance of personalization in medicine. In fact, it has become a common belief that personalized medicine is the future of medicine. The core of personalized medicine is the…

Methodology · Statistics 2020-04-30 Qiong Zhang , Amin Khademi , Yongjia Song

Experiments deliver credible treatment-effect estimates but, because they are costly, are often restricted to specific sites, small populations, or particular mechanisms. A common practice across several fields is therefore to combine…

Econometrics · Economics 2025-12-30 Aristotelis Epanomeritakis , Davide Viviano

In high-stakes settings where machine learning models are used to automate decision-making about individuals, the presence of algorithmic bias can exacerbate systemic harm to certain subgroups of people. These biases often stem from the…

Machine Learning · Computer Science 2026-04-07 Erin Tan , Judy Hanwen Shen , Irene Y. Chen

As technology continues to advance, there is increasing concern about individuals being left behind. Many businesses are striving to adopt responsible design practices and avoid any unintended consequences of their products and services,…

Social and Information Networks · Computer Science 2020-02-17 Guillaume Saint-Jacques , Amir Sepehri , Nicole Li , Igor Perisic

The principle of allocating an equal number of patients to each arm in a randomized controlled trial remains widely believed to be optimal for maximising statistical power. However, this long-held belief only holds true if the treatment…

Methodology · Statistics 2025-10-15 Lukas Pin , Stef Baas , David S. Robertson , Sofía S. Villar

I develop a model of a randomized experiment with a binary intervention and a binary outcome. Potential outcomes in the intervention and control groups give rise to four types of participants. Fixing ideas such that the outcome is…

Methodology · Statistics 2020-07-24 Amanda Kowalski

Practitioners in medicine, business, political science, and other fields are increasingly aware that decisions should be personalized to each patient, customer, or voter. A given treatment (e.g. a drug or advertisement) should be…

Machine Learning · Statistics 2018-06-15 Alejandro Schuler , Michael Baiocchi , Robert Tibshirani , Nigam Shah

In settings where interference between units is possible, we define the prevalence of indirect effects to be the number of units who are affected by the treatment of others. This quantity does not fully identify an indirect effect, but may…

Methodology · Statistics 2024-01-18 David Choi

AI models are often evaluated based on their ability to predict the outcome of interest. However, in many AI for social impact applications, the presence of an intervention that affects the outcome can bias the evaluation. Randomized…

Machine Learning · Computer Science 2025-11-18 Winston Chen , Michael W. Sjoding , Jenna Wiens

It is increasingly common to augment randomized controlled trial with external controls from observational data, to evaluate the treatment effect of an intervention. Traditional approaches to treatment effect estimation involve ambiguous…

Methodology · Statistics 2025-03-28 Bo Liu , Laine Thomas , Rury R. Holman , Fan Li

Interference occurs when the potential outcomes of a unit depend on the treatment of others. Interference can be highly heterogeneous, where treating certain individuals might have a larger effect on the population's overall outcome. A…

Methodology · Statistics 2025-04-11 Samantha G Dean , Georgia Papadogeorgou , Laura Forastiere

Individuals are often influenced by the behavior of others, for instance because they wish to obtain the benefits of coordinated actions or infer otherwise inaccessible information. In such situations this social influence decreases the ex…

Adaptation and Self-Organizing Systems · Physics 2015-05-14 Richard Colbaugh , Kristin Glass , Paul Ormerod

When developing a new networking algorithm, it is established practice to run a randomized experiment, or A/B test, to evaluate its performance. In an A/B test, traffic is randomly allocated between a treatment group, which uses the new…

Networking and Internet Architecture · Computer Science 2021-10-04 Bruce Spang , Veronica Hannan , Shravya Kunamalla , Te-Yuan Huang , Nick McKeown , Ramesh Johari

Algorithmic fairness has emphasized the role of biased data in automated decision outcomes. Recently, there has been a shift in attention to sources of bias that implicate fairness in other stages in the ML pipeline. We contend that one…

Machine Learning · Computer Science 2021-09-09 Jessica Zosa Forde , A. Feder Cooper , Kweku Kwegyir-Aggrey , Chris De Sa , Michael Littman
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