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Quantifiable image patterns associated with disease progression and treatment response are critical tools for guiding individual treatment, and for developing novel therapies. Here, we show that unsupervised machine learning can identify a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Matthias Perkonigg , Nina Bastati , Ahmed Ba-Ssalamah , Peter Mesenbrink , Alexander Goehler , Miljen Martic , Xiaofei Zhou , Michael Trauner , Georg Langs

How to accurately classify and diagnose whether an individual has Coronary Stenosis (CS) without invasive physical examination? This problem has not been solved satisfactorily. To this end, the four machine learning (ML) algorithms, i.e.,…

Tissues and Organs · Quantitative Biology 2021-09-08 Weijun Zhu , Fengyuan Lu , Xiaoyu Yang , En Li

Disease classification is a crucial element of biomedical research. Recent studies have demonstrated that machine learning techniques, such as Support Vector Machine (SVM) modeling, produce similar or improved predictive capabilities in…

Machine Learning · Statistics 2017-08-02 Jessica M. Rudd

Staging of liver fibrosis is important in the diagnosis and treatment planning of patients suffering from liver diseases. Current deep learning-based methods using abdominal magnetic resonance imaging (MRI) usually take a sub-region of the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Zheyao Gao , Yuanye Liu , Fuping Wu , NanNan Shi , Yuxin Shi , Xiahai Zhuang

A wide variety of machine learning algorithms such as support vector machine (SVM), minimax probability machine (MPM), and Fisher discriminant analysis (FDA), exist for binary classification. The purpose of this paper is to provide a…

Machine Learning · Computer Science 2012-06-22 Akiko Takeda , Hiroyuki Mitsugi , Takafumi Kanamori

Globally, there is a substantial unmet need to diagnose various diseases effectively. The complexity of the different disease mechanisms and underlying symptoms of the patient population presents massive challenges to developing the early…

Machine Learning · Computer Science 2022-01-03 Md Manjurul Ahsan , Zahed Siddique

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold

Quick and accurate medical diagnosis is crucial for the successful treatment of a disease. Using machine learning algorithms, we have built two models to predict a hematologic disease, based on laboratory blood test results. In one…

Machine Learning · Statistics 2020-06-09 Gregor Gunčar , Matjaž Kukar , Mateja Notar , Miran Brvar , Peter Černelč , Manca Notar , Marko Notar

Medical researchers have solved the problem of estimating the sensitivity and specificity of binary medical diagnostic tests without gold standard tests for comparison. That problem is the same as estimating confusion matrices for…

Machine Learning · Statistics 2022-12-29 Richard Evans

Deep learning has become an extremely powerful tool for complex tasks such as image classification and segmentation. The medical industry often lacks high-quality, balanced datasets, which can be a challenge for deep learning algorithms…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Muhammad Shoaib Farooq , Ayesha Tariq

Liver diseases are a serious health concern in the world, which requires precise and timely diagnosis to enhance the survival chances of patients. The current literature implemented numerous machine learning and deep learning models to…

Data mining techniques on the biological analysis are spreading for most of the areas including the health care and medical information. We have applied the data mining techniques, such as KNN, SVM, MLP or decision trees over a unique…

Machine Learning · Statistics 2014-01-28 Sadi Evren Seker , Y. Unal , Z. Erdem , H. Erdinc Kocer

Accurate prediction and identification of variables associated with outcomes or disease states are critical for advancing diagnosis, prognosis, and precision medicine in biomedical research. Regularized regression techniques, such as lasso,…

Applications · Statistics 2025-04-14 Xiaoru Dong , Apoorva Goyal , Muxuan Liang , Maigan A. Brusko , Todd M. Brusko , Rhonda Bacher

This paper reviews a wide selection of machine learning models built to predict both the presence of diabetes and the presence of undiagnosed diabetes using eight years of National Health and Nutrition Examination Survey (NHANES) data.…

Machine Learning · Computer Science 2021-05-21 Avraham Adler

Multiple Instance Learning (MIL) is increasingly being used as a support tool within clinical settings for pathological diagnosis decisions, achieving high performance and removing the annotation burden. However, existing approaches for…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Sungrae Hong , Kyungeun Kim , Juhyeon Kim , Sol Lee , Jisu Shin , Chanjae Song , Mun Yong Yi

Coronary Artery Disease (CAD) remains a leading cause of morbidity and mortality worldwide. Early detection is critical to recover patient outcomes and decrease healthcare costs. In recent years, machine learning (ML) advancements have…

Artificial Intelligence · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

In this work we propose an approach to select the classification method and features, based on the state-of-the-art, with best performance for diagnostic support through peripheral blood smear images of red blood cells. In our case we used…

Machine Learning · Computer Science 2020-10-12 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Manuel González-Hidalgo

The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

Machine Learning · Statistics 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad

Human-in-the-loop data analysis applications necessitate greater transparency in machine learning models for experts to understand and trust their decisions. To this end, we propose a visual analytics workflow to help data scientists and…

Machine Learning · Statistics 2017-10-03 Josua Krause , Aritra Dasgupta , Jordan Swartz , Yindalon Aphinyanaphongs , Enrico Bertini

Training data is the key component in designing algorithms for medical image analysis and in many cases it is the main bottleneck in achieving good results. Recent progress in image generation has enabled the training of neural network…

Computer Vision and Pattern Recognition · Computer Science 2018-11-02 Avi Ben-Cohen , Roey Mechrez , Noa Yedidia , Hayit Greenspan