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The coronavirus disease 2019 (COVID-19) pandemic is changing and impacting lives on a global scale. In this paper, we introduce a mean-field game model in controlling the propagation of epidemics on a spatial domain. The control variable,…

Optimization and Control · Mathematics 2020-11-12 Wonjun Lee , Siting Liu , Hamidou Tembine , Wuchen Li , Stanley Osher

The SEIR model is a compartmental model used to simulate the dynamics of an epidemic. In this chapter, we introduce two control functions in the compartmental SEIR model representing vaccination and plasma transfusion. Optimal control…

Optimization and Control · Mathematics 2021-07-23 Juliana Couras , Ivan Area , Juan J. Nieto , Cristiana J. Silva , Delfim F. M. Torres

Massive vaccination against pandemics such as Coronavirus SARS-CoV-2 presents several complexities. The criteria to assess public health policies are fundamental to distribute vaccines in an effective way in order to avoid as many…

Optimization and Control · Mathematics 2023-12-01 José Luis Sainz-Pardo , José Valero

Covid-19 has caused hundred of thousands of deaths and an economic damage amounting to trillions of dollars, creating a desire for the rapid development of vaccine. Once available, vaccine is gradually produced, evoking the question on how…

Populations and Evolution · Quantitative Biology 2020-06-30 Jens Grauer , Hartmut Löwen , Benno Liebchen

The paper presents the one of possible approach to model the epidemic propagation. The proposed model is based on the mean-field control inside separate groups of population, namely, suspectable (S), infected (I), removed (R) and…

Optimization and Control · Mathematics 2021-12-24 Viktoriya Petrakova , Olga Krivorotko

Purpose: Only few companies were able to produce vaccine again COVID-19. Thus, one producer supplied it to many countries. The distribution was not effective. Some countries overstocked the vaccine while other countries were not able to buy…

Physics and Society · Physics 2024-08-20 Béla Vizvári , Gergely Kovács

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

We develop a mathematical model for transferring the vaccine BNT162b2 based on the heat diffusion equation. Then, we apply optimal control theory to the proposed generalized SEIR model. We introduce vaccination for the susceptible…

Optimization and Control · Mathematics 2022-04-22 Mohamed Abdelaziz Zaitri , Mohand Ouamer Bibi , Delfim F. M. Torres

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Social and Information Networks · Computer Science 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

Populations and Evolution · Quantitative Biology 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

The paper describes and compares three approaches to modeling an epidemic spread. The first approach is a well-known system of SIR ordinary differential equations. The second is a mean-field model, in which an isolation strategy for each…

Populations and Evolution · Quantitative Biology 2024-11-06 Viktoriya Petrakova , Olga Krivorotko

This study aims to determine an optimal control strategy for vaccine scheduling in COVID-19 pandemic treatment by converting widely acknowledged infectious disease model named SEIR into an optimal control problem. The problem is augmented…

Populations and Evolution · Quantitative Biology 2020-08-26 Syed Irfan Ali Meerza , Seyed M. Karimi , Bert B. Little , Jacek M. Zurada , Tamer Inanc

In a world being hit by waves of COVID-19, vaccination is a light on the horizon. However, the roll-out of vaccination strategies and their influence on the pandemic are still open problems. In order to compare the effect of various…

Physics and Society · Physics 2021-04-23 N. L. Barreiro , C. I. Ventura , T. Govezensky , M. Núñez , P. G. Bolcatto , R. A. Barrio

We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

Probability · Mathematics 2021-02-26 Emanuel Javier Ferreyra , Matthieu Jonckheere , Juan Pablo Pinasco

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

Populations and Evolution · Quantitative Biology 2021-08-17 Evangelos F. Magirou

With the approval of vaccines for the coronavirus disease by many countries worldwide, most developed nations have begun, and developing nations are gearing up for the vaccination process. This has created an urgent need to provide a…

Computers and Society · Computer Science 2021-02-09 Mahzabeen Emu , Dhivya Chandrasekaran , Vijay Mago , Salimur Choudhury

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

Optimization and Control · Mathematics 2024-11-08 Nelson L. Santos Junior , João A. M. Gondim

This study presents a mathematical model for optimal vaccination strategies in interconnected metropolitan areas, considering commuting patterns. It is a compartmental model with a vaccination rate for each city, acting as a control…

Populations and Evolution · Quantitative Biology 2024-04-29 Lucas Machado Moschen , María Soledad Aronna

Modeling and control of epidemics such as the novel Corona virus have assumed paramount importance at a global level. A natural and powerful dynamical modeling framework to use in this context is a continuous time Markov decision process…

Physics and Society · Physics 2023-04-13 Amal Roy , Chandramani Singh , Y. Narahari
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