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Massive sized survival datasets are becoming increasingly prevalent with the development of the healthcare industry. Such datasets pose computational challenges unprecedented in traditional survival analysis use-cases. A popular way for…

Methodology · Statistics 2023-05-09 Nir Keret , Malka Gorfine

Pooled testing (also known as group testing), where diagnostic tests are performed on pooled samples, has broad applications in the surveillance of diseases in animals and humans. An increasingly common use case is molecular xenomonitoring…

Computation · Statistics 2021-12-21 Angus McLure , Ben O'Neill , Helen Mayfield , Colleen Lau , Brady McPherson

Predictive models in acute care settings must be able to immediately recognize precipitous changes in a patient's status when presented with data reflecting such changes. Recurrent neural networks (RNNs) have become common for training and…

Machine Learning · Computer Science 2020-07-30 David Ledbetter , Eugene Laksana , Melissa Aczon , Randall Wetzel

This paper presents the recurrent estimation of distributions (RED) for modeling real-valued data in a semiparametric fashion. RED models make two novel uses of recurrent neural networks (RNNs) for density estimation of general real-valued…

Machine Learning · Computer Science 2017-05-31 Junier B. Oliva , Kumar Avinava Dubey , Barnabas Poczos , Eric Xing , Jeff Schneider

Mediation analysis is one of the most widely used statistical techniques in the social, behavioral, and medical sciences. Mediation models allow to study how an independent variable affects a dependent variable indirectly through one or…

Computation · Statistics 2022-08-18 Andreas Alfons , Nüfer Y. Ateş , Patrick J. F. Groenen

The longevity R package provides provide maximum likelihood estimation routine for modelling of survival data that are subject to non-informative censoring and truncation mechanisms. It includes a selection of 12 parametric models of…

Applications · Statistics 2023-11-17 Léo R. Belzile

Time series segmentation aims to identify potential change-points in a sequence of temporally dependent data, so that the original sequence can be partitioned into several homogeneous subsequences. It is useful for modeling and predicting…

Computation · Statistics 2024-04-12 Shubo Sun , Zifeng Zhao , Feiyu Jiang , Xiaofeng Shao

In studies of recurrent events, joint modeling approaches are often needed to allow for potential dependent censoring by a terminal event such as death. Joint frailty models for recurrent events and death with an additional dependence…

Methodology · Statistics 2023-04-25 Marie Böhnstedt , Jutta Gampe , Monique A. A. Caljouw , Hein Putter

We present a novel Recurrent Graph Network (RGN) approach for predicting discrete marked event sequences by learning the underlying complex stochastic process. Using the framework of Point Processes, we interpret a marked discrete event…

Machine Learning · Computer Science 2022-08-12 Saurabh Dash , Xueyuan She , Saibal Mukhopadhyay

We provide precise conditions for nonparametric identification of causal effects by high-frequency event study regressions, which have been used widely in the recent macroeconomics, financial economics and political economy literatures. The…

Econometrics · Economics 2025-07-24 Alessandro Casini , Adam McCloskey

Many important social phenomena are characterized by repeated interactions among individuals over time such as email exchanges in an organization or face-to-face interactions in a classroom. To understand the underlying mechanisms of social…

Social and Information Networks · Computer Science 2025-01-09 Rumana Lakdawala , Joris Mulder , Roger Leenders

This text is a conceptual introduction to mixed effects modeling with linguistic applications, using the R programming environment. The reader is introduced to linear modeling and assumptions, as well as to mixed effects/multilevel…

Computation and Language · Computer Science 2013-08-27 Bodo Winter

The prediction interval is gaining prominence in meta-analysis as it enables the assessment of uncertainties in treatment effects and heterogeneity between studies. However, coverage probabilities of the current standard method for…

Methodology · Statistics 2021-10-18 Kengo Nagashima , Hisashi Noma , Toshi A. Furukawa

The modeling of time-to-event data, also known as survival analysis, requires specialized methods that can deal with censoring and truncation, time-varying features and effects, and that extend to settings with multiple competing events.…

Machine Learning · Statistics 2021-04-20 Andreas Bender , David Rügamer , Fabian Scheipl , Bernd Bischl

Models that can simulate how environments change in response to actions can be used by agents to plan and act efficiently. We improve on previous environment simulators from high-dimensional pixel observations by introducing recurrent…

Artificial Intelligence · Computer Science 2017-04-20 Silvia Chiappa , Sébastien Racaniere , Daan Wierstra , Shakir Mohamed

In health cohort studies, repeated measures of markers are often used to describe the natural history of a disease. Joint models allow to study their evolution by taking into account the possible informative dropout usually due to clinical…

The R package BigVAR allows for the simultaneous estimation of high-dimensional time series by applying structured penalties to the conventional vector autoregression (VAR) and vector autoregression with exogenous variables (VARX)…

Computation · Statistics 2017-02-24 William Nicholson , David Matteson , Jacob Bien

Time-to-event endpoints are frequently used as outcomes in oncology and other disease areas where the outcome of interest may not be observed within a predetermined period. Although many analytical methods address the challenges of…

Methodology · Statistics 2026-04-14 Chen-Yen Lin , Susan Halabi , Taehwa Choi

This paper provides guidance for researchers with some mathematical background on the conduct of time-to-event analysis in observational studies based on intensity (hazard) models. Discussions of basic concepts like time axis, event…

Event datasets are sequences of events of various types occurring irregularly over the time-line, and they are increasingly prevalent in numerous domains. Existing work for modeling events using conditional intensities rely on either using…

Machine Learning · Computer Science 2020-02-25 Tian Gao , Dharmashankar Subramanian , Karthikeyan Shanmugam , Debarun Bhattacharjya , Nicholas Mattei