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Branching process inspired models are widely used to estimate the effective reproduction number -- a useful summary statistic describing an infectious disease outbreak -- using counts of new cases. Case data is a real-time indicator of…

Methodology · Statistics 2023-10-03 Isaac H. Goldstein , Jon Wakefield , Volodymyr M. Minin

An evolving yeast colony is simulated by means of a cellular automaton that takes care of many important features of the system under study. A complete survey of the properties of the colony is done and a set of scaling relations is found,…

Statistical Mechanics · Physics 2007-05-23 Lorenzo Fortunato

We study the multi-strategy stochastic evolutionary game with death-birth updating in expanding spatial populations of size $N\to \infty$. The model is a voter model perturbation. For typical populations, we require perturbation strengths…

Probability · Mathematics 2021-01-13 Yu-Ting Chen

We present a generic mechanism by which reproducing microorganisms, with a diffusivity that depends on the local population density, can form stable patterns. It is known that a decrease of swimming speed with density can promote separation…

Populations and Evolution · Quantitative Biology 2010-07-13 M. E. Cates , D. Marenduzzo , I. Pagonabarraga , J. Tailleur

In the modeling of parasite transmission dynamics, understanding the reproductive characteristics of these parasites is crucial. This paper presents a mathematical model that explores the reproductive behavior of dioecious parasites and its…

Populations and Evolution · Quantitative Biology 2023-05-30 Gonzalo Maximiliano Lopez , Juan Pablo Aparicio

Our purpose is to estimate the posterior distribution of the parameters of interest for controlled branching processes (CBPs) without prior knowledge of the maximum number of offspring that an individual can give birth to and without…

Methodology · Statistics 2021-08-10 Miguel González , Carmen Minuesa , Inés del Puerto

Background Elimination of malaria can only be achieved through removal of all vectors or complete depletion of the infectious reservoir in humans. Mechanistic models can be built to synthesize diverse observations from the field collected…

Populations and Evolution · Quantitative Biology 2015-07-13 Jaline Gerardin , Andre Lin Ouedraogo , Kevin A. McCarthy , Bocar Kouyate , Philip A. Eckhoff , Edward A. Wenger

We present a continuous time model of maturation and survival, obtained as the limit of a compartmental evolution model when the number of compartments tends to infinity. We establish in particular an explicit formula for the law of the…

Probability · Mathematics 2008-08-13 Djalil Chafai , Didier Concordet

Comparisons of different treatments or production processes are the goals of a significant fraction of applied research. Unsurprisingly, two-sample problems play a main role in Statistics through natural questions such as `Is the the new…

Methodology · Statistics 2017-09-05 P. C. Álvarez-Esteban , E. del Barrio , J. A. Cuesta-Albertos , C. Matrán

Various rod-shaped bacteria such as the canonical gram negative Escherichia coli or the well-studied gram positive Bacillus subtilis divide symmetrically after they approximately double their volume. Their size at division is not constant,…

Cell Behavior · Quantitative Biology 2015-06-18 Ariel Amir

We analyze an epidemiological model to evaluate the effectiveness of multiple means of control in malaria-endemic areas. The mathematical model consists of a system of several ordinary differential equations, and is based on a…

Populations and Evolution · Quantitative Biology 2023-06-28 Jean Claude Kamgang , Christopher Thron

In this paper we analyze the equilibrium properties of a large class of stochastic processes describing the fundamental biological process within bacterial cells, {\em the production process of proteins}. Stochastic models classically used…

Molecular Networks · Quantitative Biology 2019-10-17 Philippe Robert

Bacterial cells navigate around their environment by directing their movement along chemical gradients. This process, known as chemotaxis, can promote the rapid expansion of bacterial populations into previously unoccupied territories.…

Populations and Evolution · Quantitative Biology 2022-06-08 Avaneesh V. Narla , Jonas Cremer , Terry Hwa

We investigate the protein expression pattern of the lamB gene in Escherichia coli LE392. The gene product LamB is an important membrane protein for maltose transport into cells but it is also exploited by bacteriophage lambda for…

Cell Behavior · Quantitative Biology 2008-08-08 Emily Chapman-McQuiston , Chuck Yeung , X. L. Wu

One of the most popular models for quantitatively understanding the emergence of drug resistance both in bacterial colonies and in malignant tumors was introduced long ago by Luria and Delbr\"uck. Here, individual resistant mutants emerge…

Populations and Evolution · Quantitative Biology 2014-04-10 David A. Kessler , Herbert Levine

Chloroplasts regulate their growth to optimize photosynthesis. Quantitative data shows that the ratio of total chloroplast area to mesophyll cell area is constant across different cells within a single species, and also across species.…

Subcellular Processes · Quantitative Biology 2015-09-03 Kelly M. Paton , Lisa Anderson , Pauline Flottat , Eric N. Cytrynbaum

The presence of protein aggregates in cells is a known feature of many human age-related diseases, such as Huntington's disease. Simulations using fixed parameter values in a model of the dynamic evolution of expanded polyglutamine (PolyQ)…

In this paper, we introduce a modified epidemic model on regular and scale-free networks respectively. We consider the birth rate $\delta$, cure rate $\gamma$, infection rate $\lambda$, $\alpha$ from the infectious disease, and death rate…

Populations and Evolution · Quantitative Biology 2013-02-14 Jingzhou Liu

This paper presents an interesting experimental example of voter-model statistics in biology. In recent work on mouse tail-skin, where proliferating cells are confined to a two-dimensional layer, we showed that cells proliferate and…

Biological Physics · Physics 2009-11-13 Allon M. Klein , David P. Doupe , Philip H. Jones , Benjamin D. Simons

Metagenomics has revealed hundreds of bacterial species in almost all microbiota. In a few well-studied cases, bacterial communities have been observed to coordinate their metabolic fluxes. In principle, bacteria can divide tasks to reap…

Populations and Evolution · Quantitative Biology 2016-04-12 Thibaud Taillefumier , Anna Posfai , Yigal Meir , Ned S. Wingreen
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