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Digitization of histopathology slides has led to several advances, from easy data sharing and collaborations to the development of digital diagnostic tools. Deep learning (DL) methods for classification and detection have shown great…
In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…
Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…
In patients with biochemical recurrence of prostate cancer and negative PSMA PET/CT, radiomics features extracted from recurrence-prone organs can predict clinical progression and progression-free survival. In a cohort of 132 patients,…
Surgery planning in patients diagnosed with brain tumor is dependent on their survival prognosis. A poor prognosis might demand for a more aggressive treatment and therapy plan, while a favorable prognosis might enable a less risky surgery…
Understanding the progression of cancer is crucial for defining treatments for patients. The objective of this study is to automate the detection of metastatic liver disease from free-style computed tomography (CT) radiology reports. Our…
Cancer is a primary cause of morbidity and mortality worldwide. The radiotherapy plays a more and more important role in cancer treatment. In the radiotherapy, the dose distribution maps in patient need to be calculated and evaluated for…
Skin cancer is among the most common cancer types. Dermoscopic image analysis improves the diagnostic accuracy for detection of malignant melanoma and other pigmented skin lesions when compared to unaided visual inspection. Hence,…
Multiple Myeloma (MM) is a blood cancer implying bone marrow involvement, renal damages and osteolytic lesions. The skeleton involvement of MM is at the core of the present paper, exploiting radiomics and artificial intelligence to identify…
The Hausdorff Distance (HD) is widely used in evaluating medical image segmentation methods. However, existing segmentation methods do not attempt to reduce HD directly. In this paper, we present novel loss functions for training…
The prevalence of breast cancer continues to grow, affecting about 300,000 females in the United States in 2023. However, there are different levels of severity of breast cancer requiring different treatment strategies, and hence, grading…
Radiotherapy is the main treatment modality for nasopharynx cancer. Delineation of Gross Target Volume (GTV) from medical images such as CT and MRI images is a prerequisite for radiotherapy. As manual delineation is time-consuming and…
Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic…
Brain metastasis segmentation in MRI remains a formidable challenge due to diminutive lesion sizes (5-15 mm) and extreme class imbalance (less than 2% tumor volume). While soft-attention CNNs are widely used, we identify a critical failure…
Histopathology image segmentation is essential for delineating tissue structures in skin cancer diagnostics, but modeling spatial context and inter-tissue relationships remains a challenge, especially in regions with overlapping or…
Colorectal cancer (CRC) remains a significant cause of cancer-related mortality, despite the widespread implementation of prophylactic initiatives aimed at detecting and removing precancerous polyps. Although screening effectively reduces…
Colorectal cancer is a prevalent form of cancer, and many patients develop colorectal cancer liver metastasis (CRLM) as a result. Early detection of CRLM is critical for improving survival rates. Radiologists usually rely on a series of…
Purpose: This study investigated how nodule segmentation and surrounding peritumoral regions influence radionics-based lung cancer classification. Methods: Using 3D CT scans with bounding box annotated nodules, we generated 3D segmentations…
Melanoma is a sort of skin cancer that starts in the cells known as melanocytes. It is more dangerous than other types of skin cancer because it can spread to other organs. Melanoma can be fatal if it spreads to other parts of the body.…
Detailed pulmonary airway segmentation is a clinically important task for endobronchial intervention and treatment of peripheral located lung cancer lesions. Convolutional Neural Networks (CNNs) are promising tools for medical image…