Related papers: Identification-Detection Group Testing Protocols f…
We analyse prior risk factors for severe, critical or fatal courses of Covid-19 based on a retrospective cohort using claims data of the AOK Bayern. As our main methodological contribution, we avoid prior grouping and pre-selection of…
Detection of rare variants by resequencing is important for the identification of individuals carrying disease variants. Rapid sequencing by new technologies enables low-cost resequencing of target regions, although it is still prohibitive…
This paper presents methods to choose individuals to test for infection during a pandemic such as COVID-19, characterized by high contagion and presence of asymptomatic carriers. The smart-testing ideas presented here are motivated by…
Fast testing can help mitigate the coronavirus disease 2019 (COVID-19) pandemic. Despite their accuracy for single sample analysis, infectious diseases diagnostic tools, like RT-PCR, require substantial resources to test large populations.…
Pooling specimens, a well-accepted sampling strategy in biomedical research, can be applied to reduce the cost of studying biomarkers. Even if the cost of a single assay is not a major restriction in evaluating biomarkers, pooling can be a…
There are many hard-to-reconcile numbers circulating concerning Covid-19. Using reports from random testing, the fatality ratio per infection is evaluated and used to extract further information on the actual fraction of infections and the…
During the SARS-CoV-2 pandemic, polymerase chain reaction (PCR) and lateral flow device (LFD) tests were frequently deployed to detect the presence of SARS-CoV-2. Many of these tests were singleplex, and only tested for the presence of a…
Accurate detection of infected individuals is one of the critical steps in stopping any pandemic. When the underlying infection rate of the disease is low, testing people in groups, instead of testing each individual in the population, can…
This paper considers the noisy group testing problem where among a large population of items some are defective. The goal is to identify all defective items by testing groups of items, with the minimum possible number of tests. The focus of…
Controlling the COVID-19 pandemic is an urgent global challenge. The rapid geographic spread of SARS-CoV-2 directly reflects the social structure. Before effective vaccines and treatments are widely available, we have to rely on…
We propose a compressed sensing-based testing approach with a practical measurement design and a tuning-free and noise-robust algorithm for detecting infected persons. Compressed sensing results can be used to provably detect a small number…
The principal goal of Group Testing (GT) is to identify a small subset of "defective" items from a large population, by grouping items into as few test pools as possible. The test outcome of a pool is positive if it contains at least one…
High-dimensional group inference is an essential part of statistical methods for analysing complex data sets, including hierarchical testing, tests of interaction, detection of heterogeneous treatment effects and inference for local…
Pooled testing is widely used for screening for viral or bacterial infections with low prevalence when individual testing is not cost-efficient. Pooled testing with qualitative assays that give binary results has been well-studied. However,…
Distinguishing COVID-19 from other flu-like illnesses can be difficult due to ambiguous symptoms and still an initial experience of doctors. Whereas, it is crucial to filter out those sick patients who do not need to be tested for…
The outbreak of the novel coronavirus (COVID-19) is unfolding as a major international crisis whose influence extends to every aspect of our daily lives. Effective testing allows infected individuals to be quarantined, thus reducing the…
Combinatorial group testing (CGT) is used to identify defective items from a set of items by grouping them together and performing a small number of tests on the groups. Recently, group testing has been used to design efficient COVID-19…
For testing the statistical significance of a treatment effect, we usually compare between two parts of a population, one is exposed to the treatment, and the other is not exposed to it. Standard parametric and nonparametric two-sample…
Randomization tests are a popular method for testing causal effects in clinical trials with finite-sample validity. In the presence of heterogeneous treatment effects, it is often of interest to select a subgroup that benefits from the…
The paper is focused on the problem of estimating the probability $p$ of individual contaminated sample, under group testing. The precision of the estimator is given by the probability of proportional closeness, a concept defined in the…