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When the infection prevalence of a disease is low, Dorfman showed 80 years ago that testing groups of people can prove more efficient than testing people individually. Our goal in this paper is to propose new group testing algorithms that…

Methodology · Statistics 2020-07-23 Marco Cuturi , Olivier Teboul , Quentin Berthet , Arnaud Doucet , Jean-Philippe Vert

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

During the COVID-19 pandemic, many institutions such as universities and workplaces implemented testing regimens with every member of some population tested longitudinally, and those testing positive isolated for some time. Although the…

Methodology · Statistics 2023-04-19 Patrick M. Schnell , Matthew Wascher , Grzegorz A. Rempala

We consider a novel method to increase the reliability of COVID-19 virus or antibody tests by using specially designed pooled testings. Instead of testing nasal swab or blood samples from individual persons, we propose to test mixtures of…

Quantitative Methods · Quantitative Biology 2020-07-30 Jirong Yi , Myung Cho , Xiaodong Wu , Weiyu Xu , Raghu Mudumbai

Detection of defective members of large populations has been widely studied in the statistics community under the name "group testing", a problem which dates back to World War II when it was suggested for syphilis screening. There the main…

Information Theory · Computer Science 2009-09-28 Mahdi Cheraghchi , Ali Hormati , Amin Karbasi , Martin Vetterli

Group testing is utilized in the case when we want to find a few defectives among large amount of items. Testing n items one by one requires n tests, but if the ratio of defectives is small, group testing is an efficient way to reduce the…

Computation · Statistics 2024-05-16 Hiroyasu Matsushima , Yusuke Tajima , Xiao-Nan Lu , Masakazu Jimbo

The group testing problem asks for efficient pooling schemes and algorithms that allow to screen moderately large numbers of samples for rare infections. The goal is to accurately identify the infected samples while conducting the least…

Artificial Intelligence · Computer Science 2021-05-19 AminCoja-Oghlan , Max Hahn-Klimroth , Philipp Loick , Manuel Penschuck

We consider a new group testing model wherein each item is a binary random variable defined by an a priori probability of being defective. We assume that each probability is small and that items are independent, but not necessarily…

Information Theory · Computer Science 2018-07-24 Tongxin Li , Chun Lam Chan , Wenhao Huang , Tarik Kaced , Sidharth Jaggi

We study the problem usually referred to as group testing in the context of COVID-19. Given n samples collected from patients, how should we select and test mixtures of samples to maximize information and minimize the number of tests? Group…

Machine Learning · Computer Science 2020-08-07 Louis Abraham , Gary Becigneul , Benjamin Coleman , Bernhard Scholkopf , Anshumali Shrivastava , Alexander Smola

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

We propose a novel infection spread model based on a random connection graph which represents connections between $n$ individuals. Infection spreads via connections between individuals and this results in a probabilistic cluster formation…

Information Theory · Computer Science 2022-03-30 Batuhan Arasli , Sennur Ulukus

We consider dynamical group testing problem with a community structure. With a discrete-time SIR (susceptible, infectious, recovered) model, we use Dorfman's two-step group testing approach to identify infections, and step in whenever…

Methodology · Statistics 2022-01-21 Mustafa Doger , Sennur Ulukus

In epidemic or pandemic situations, resources for testing the infection status of individuals may be scarce. Although group testing can help to significantly increase testing capabilities, the (repeated) testing of entire populations can…

Populations and Evolution · Quantitative Biology 2021-10-29 Günther Koliander , Georg Pichler

Group testing is a method of identifying infected patients by performing tests on a pool of specimens collected from patients. For the case in which the test returns a false result with finite probability, we propose Bayesian inference and…

Machine Learning · Statistics 2020-07-15 Ayaka Sakata

Group testing can help maintain a widespread testing program using fewer resources amid a pandemic. In a group testing setup, we are given n samples, one per individual. Each individual is either infected or uninfected. These samples are…

Signal Processing · Electrical Eng. & Systems 2023-07-19 Shu-Jie Cao , Ritesh Goenka , Chau-Wai Wong , Ajit Rajwade , Dror Baron

The first part of the paper presents a review of the gold-standard testing protocol for Covid-19, real-time, reverse transcriptase PCR, and its properties and associated measurement data such as amplification curves that can guide the…

Quantitative Methods · Quantitative Biology 2021-06-08 Ryan Gabrys , Srilakshmi Pattabiraman , Vishal Rana , João Ribeiro , Mahdi Cheraghchi , Venkatesan Guruswami , Olgica Milenkovic

We study a dynamic infection spread model, inspired by the discrete time SIR model, where infections are spread via non-isolated infected individuals. While infection keeps spreading over time, a limited capacity testing is performed at…

Methodology · Statistics 2022-01-25 Batuhan Arasli , Sennur Ulukus

We have a large number of samples and we want to find the infected ones using as few number of tests as possible. We can use group testing which tells about a small group of people whether at least one of them is infected. Group testing is…

Quantitative Methods · Quantitative Biology 2020-05-07 Endre Csóka

We consider the optimal strategy for laboratory testing of biological samples when we wish to know the results for each sample rather than the average prevalence of positive samples. If the proportion of positive samples is low considerable…

Quantitative Methods · Quantitative Biology 2010-07-29 Brian G. Williams

The use of group testing to locate all instances of disease in a large population of blood samples was first considered seventy years ago. Since then, several methods have been used to approximate the minimum expected number of tests. The…

Applications · Statistics 2015-03-24 Seth Zimmerman