Related papers: Digestive System Dynamics in Molecular Communicati…
To advance understanding of cellular metabolism and reduce batch-to-batch variability in cell culture processes, this study introduces a multi-scale hybrid modeling framework designed to simulate and predict the dynamic behavior of CHO cell…
The pursuit of quality improvements and accountability in the food supply chains, especially how they relate to food-related outcomes, such as hunger, has become increasingly vital, necessitating a comprehensive approach that encompasses…
The prevalence of Diabetes mellitus (DM) in the Middle East is exceptionally high as compared to the rest of the world. In fact, the prevalence of diabetes in the Middle East is 17-20%, which is well above the global average of 8-9%.…
This study presents an integrated approach to understanding epidemic dynamics through a stochastic spatio-temporal simulation model on a multiplex network, blending physical and informational layers. The physical layer maps the geographic…
Food is central to life. Food provides us with energy and foundational building blocks for our body and is also a major source of joy and new experiences. A significant part of the overall economy is related to food. Food science,…
High-throughput experimental techniques and bioinformatics tools make it possible to obtain reconstructions of the metabolism of microbial species. Combined with mathematical frameworks such as flux balance analysis, which assumes that…
Intracellular transport processes are essential to the healthy development of many organisms as well as more generally to healthy cellular function. The complex dynamics and interactions between protein molecules and filaments on different…
Communication and coordination play a major role in the ability of bacterial cells to adapt to ever changing environments and conditions. Recent work has shown that such coordination underlies several aspects of bacterial responses…
The present paper is devoted to the investigation of the long time dynamics for a double free boundary system with nonlocal diffusions, which models the infectious diseases transmitted via digestive system such as fecal-oral diseases,…
Linear constrained optimization techniques have been applied to many real-world settings. In recent years, inferring the unknown parameters and functions inside an optimization model has also gained traction. This inference is often based…
In many sensory systems, transmembrane receptors are spatially organized in large clusters. Such arrangement may facilitate signal amplification and the integration of multiple stimuli. However, this organization likely also affects the…
Glucose is a primary energy source for cancer cells. Several lines of evidence support the idea that monocarboxylate transporters, such as MCT1, elicit metabolic reprogramming of cancer cells in glucose-poor environments, allowing them to…
Non-communicable diseases like diabetes, obesity and certain forms of cancer have been increasing in many countries at alarming levels. A difficulty in the conception of policies to reverse these trends is the identification of the drivers…
Air transport systems are highly dynamic at temporal scales from minutes to years. This dynamic behavior not only characterizes the evolution of the system but also affect the system's functioning. Understanding the evolutionary mechanisms…
This letter develops a one-dimensional (1D) diffusion-based molecular communication system to analyze channel responses between a single transmitter (TX) and two fully-absorbing receivers (RXs). Incorporating molecular degradation in the…
Directional chemosensing is ubiquitous in cell biology, but some cells such as mating yeast paradoxically degrade the signal they aim to detect. While the data processing inequality suggests that such signal modification cannot increase the…
Intercellular signaling has an important role in organism development, but not all communication occurs using the same mechanism. Here, we analyze the energy efficiency of intercellular signaling by two canonical mechanisms: diffusion of…
Smog, as a form of air pollution, poses as a serious problem to the environment, health, and economy of the world[1-4] . Previous studies on smog mostly focused on the components and the effects of smog [5-10]. However, as the smog happens…
[Background] Several studies have mentioned network modularity -- that a network can easily be decomposed into subgraphs that are densely connected within and weakly connected between each other -- as a factor affecting metabolic…
Microbial ecosystems are commonly modeled by fixed interactions between species in steady exponential growth states. However, microbes often modify their environments so strongly that they are forced out of the exponential state into…